01.03.2013 Views

3. Umbruch 4.4..2005 - Online Pot

3. Umbruch 4.4..2005 - Online Pot

3. Umbruch 4.4..2005 - Online Pot

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Cannabinoids in appetite and obesity 229<br />

4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a new potent and selective antagonist of<br />

the CB1 cannabinoid receptor: biochemical and pharmacological characterizaztion. J Pharmacol<br />

Exp Ther 310: 905–914<br />

38 Fong MT, Goulet M, Hagman W, Plummer C, Finke P, Mills S, Shah S, Truong Q., Shen C, Lao,<br />

J, Van der Ploeg L (2003) Biological and pharmacological activity of new CB1R inverse agonist,<br />

2003 Symposium on the Cannabinoids p 1, International Cannabinoid Research Society,<br />

Burlington, Vermont<br />

39 Smith R.A, O’Connor SJ, Wirtz SN, Wong WC, Choi S, Kluender HC, Su N, Wang G, Achebe F,<br />

Ying S (2003) Imidazole-4-carboxamide derivatives, preparation and use thereof for the treatment<br />

of obesity. International Patent Application WO 03/040107<br />

40 Le Fur G, Arnone M, Rinaldi-Carmona M, Barth F, Heshmati H (2001) SR141716, a selective<br />

antagonist of CB1 receptors and obesity, 2001 Symposium on the Cannabinoids p.101<br />

International Cannabinoid Research Society, Burlington, Vermont<br />

41 Jensen M, Abu-Lebdeh H, Geohas J, Brazg R, Block M, Noveck R, Free R (2004) The selective<br />

CB1 receptor antagonist rimonabant reduces body weight and waist circumference in obese subjects.<br />

Int J Obesity 28 (Suppl. 1): Abst T5:O2-001<br />

42 Dale L, Anthenelli R, Després JP, Golay A, Sjostrom L (2004) Effects of rimonabant in the reduction<br />

of major cardiovascular risk factors: results from the STRATUS-US trial (Smoking cessation<br />

in smokers motivated to quit) and the RIO-LIPIDS trial (Weight reduction and metabolic effects<br />

in overweight/obese patients with dyslipidemia). American College of Cardiology Annual<br />

Scientific Sessions, Presentation 409-1, March 7–10, 2004, New Orleans<br />

43 Houri M, Pratley RE (2005) Rimonabant: a novel treatment for obesity and the metabolic syndrome.<br />

Curr Diab Rep 5: 43–44<br />

44 Van Gaal L (2004) RIO-EUROPE: a randomized double-blind study of weight reducing effect and<br />

safety of rimonabant in obese patients with or without comorbidities, European Society of<br />

Cardiology Congress, Presentation 106, August 28–September 1, 2004, Munich<br />

45 Schwartz MW, Woods SC, Porte D, Jr, Seeley RJ, Baskin DG (2000) Central nervous system control<br />

of food intake. Nature 404: 661–671<br />

46 Rinaldi-Carmona M, Barth F, Millan J, Derocq JM, Casellas P, Congy C, Oustric D, Sarran M,<br />

Bouaboula M, Calandra, Le Fur G (1998) SR 144528, the first potent and selective antagonist of<br />

the CB2 cannabinoid receptor. The. J Pharmacol Exp Ther 284: 644–650<br />

47 Poncelet M, Maruani J, Calassi R, Soubrie P (2003) Overeating, alcohol and sucrose consumption<br />

decrease in CB1 receptor deleted mice. Neurosci Lett 343: 216–218<br />

48 Hilairet S, Bouaboula M, Carriere D, Le Fur G, Casellas P (2003) Hypersensitization of the<br />

Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist,<br />

SR141716. The. J Biol Chem 278: 23731–23737<br />

49 Verty AN, McFarlane JR, McGregor IS, Mallet PE (2004) Evidence for an interaction between<br />

CB1 cannabinoid and melanocortin MCR-4 receptors in regulating food intake. Endocrinology<br />

145: 3224–3231<br />

50 Cohen C, Perrault G, Voltz C, Steinberg R, Soubrie P (2002) SR141716, a central cannabinoid<br />

(CB1) receptor antagonist, blocks the motivational and dopamine-releasing effects of nicotine in<br />

rats. Behavi Pharmacol 13: 451–463<br />

51 Solinas M, Panlilio LV, Antoniou K, Pappas LA, Goldberg SR (2003) The cannabinoid CB1<br />

antagonist N-piperidinyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide<br />

(SR-141716A) differentially alters the reinforcing effects of heroin under continuous reinforcement,<br />

fixed ratio, and progressive ratio schedules of drug self-administration in rats. The. J<br />

Pharmacol Exp Ther 306: 93–102<br />

52 Deroche-Gamonet V, Le Moal M, Piazza PV, Soubrie P (2001) SR141716, a CB1 receptor antagonist,<br />

decreases the sensitivity to the reinforcing effects of electrical brain stimulation in rats.<br />

Psychopharmacologia 157: 254–259<br />

53 Kirkham TC, Williams CM (2001) Synergistic efects of opioid and cannabinoid antagonists on<br />

food intake. Psychopharmacologia 153: 267–270<br />

54 Chen RZ, Huang RR, Shen CP, MacNeil DJ, Fong TM (2004) Synergistic effects of cannabinoid<br />

inverse agonist AM251 and opioid antagonist nalmefene on food intake in mice. Brain Res 999:<br />

227–230<br />

55 Croci T, Landi M, Manara L, Rinaldi-Carmona M (2002) Body weight curbing and respiratory<br />

quotient lowering effect of the cannabinoid CB1 receptor antagonist SR141716 (Rimonabant) in<br />

rats. IUPHAR Meeting, July 7–12, 2002, San Fransico, CA

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!