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Beyond Borders: Global biotechnology report 2010

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To our clients and friends<br />

As economies around the world begin to recover from the worst<br />

economic crisis since the Great Depression, it is clear that a “new<br />

normal” is emerging. Among other things, this is a world in which<br />

capital flows are far more constrained than during the easy moneyfueled<br />

decade that preceded the downturn. What impact has this<br />

capital-constrained environment had on <strong>biotechnology</strong> — a business<br />

that is based on an enormous hunger for capital coupled with an<br />

exceptionally long path to commercial payback?<br />

We set out to answer that question in this year’s <strong>Beyond</strong> borders.<br />

As usual, we analyze key indicators of the industry’s performance:<br />

financing activity, deal trends, financial results, pipeline strength<br />

and product approvals. While the overall results are robust, the gap<br />

between the industry’s haves and its have-nots has widened.<br />

Our <strong>Global</strong> introduction article pulls together these trends and<br />

assesses their implications for <strong>biotechnology</strong> companies. In<br />

particular, we focus on new models and creative approaches that<br />

companies and investors are taking to adapt to today’s challenging<br />

economic climate. Accompanying our article are six Perspectives<br />

for the new normal by leaders of companies that are using<br />

innovative approaches to finance companies, raise capital, conduct<br />

R&D and structure deals.<br />

The common thread that runs through this discussion — indeed, the<br />

mantra of the new normal — is the search for efficiency. In a time of<br />

diminished means, key constituents in the <strong>biotechnology</strong><br />

ecosystem — investors, pharmaceutical companies, payors,<br />

governments and biotech firms — need to do more with less.<br />

Companies that are able to develop creative solutions to boost<br />

efficiency will be best positioned to succeed in the new normal.<br />

Readers of <strong>Beyond</strong> borders will notice some structural changes<br />

in this year’s <strong>report</strong>. In prior years, we organized the <strong>report</strong> by<br />

geography, with sections on the Americas, Europe and Asia-Pacific.<br />

This year, we have instead organized the <strong>report</strong> thematically.<br />

The <strong>Global</strong> perspective section brings together our point of view<br />

on salient trends and implications as well as some perspectives<br />

from company leaders. This is followed by a Country profiles<br />

section, where we summarize key developments in countries with<br />

developing <strong>biotechnology</strong> sectors. In the Industry performance<br />

section, we analyze data from locations with established<br />

<strong>biotechnology</strong> centers: the US, Europe, Canada and Australia. We<br />

think this allows us to more appropriately analyze developments<br />

in markets of different maturity and allows readers to more easily<br />

access and compare thematic trends.<br />

Ernst & Young’s life sciences professionals stand ready to help you<br />

as you navigate the unprecedented challenges and opportunities<br />

in the new normal.<br />

Glen T. Giovannetti<br />

<strong>Global</strong> Biotechnology Leader<br />

<strong>Global</strong> Life Sciences Center<br />

Ernst & Young<br />

Gautam Jaggi<br />

Managing Editor, <strong>Beyond</strong> borders<br />

<strong>Global</strong> Life Sciences Center<br />

Ernst & Young

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