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Beyond Borders: Global biotechnology report 2010

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“The biggest challenge for Western<br />

companies is to really understand the<br />

local market, including the local culture,<br />

available resources, infrastructure and<br />

Government policies.”<br />

So my advice to companies moving into China is threefold. First,<br />

really do your homework and understand the local market. Second,<br />

tailor your business model to your specific needs and the nature<br />

of the local market. Third, partner with local entities — companies,<br />

governments, and academic and medical institutions — to navigate<br />

the market.<br />

Mazumdar-Shaw: I agree completely that partnering with local<br />

companies has its merits. For example, as national health systems<br />

struggle with containing costs, they will inevitably need to rely<br />

on tender-based procurement from the private sector. But to win<br />

these sizeable contracts, it is important to partner with a regional<br />

company that knows the landscape and can bid much more<br />

aggressively than a big or foreign firm could do on its own.<br />

One other area that is often underestimated is the significant<br />

investment — both in time and money — necessary to establish your<br />

brand in a new market. Partnering with a regional company and<br />

leveraging its distribution network will allow much faster market<br />

entry and bigger gains in market share.<br />

But probably the biggest risk and challenge to any new market,<br />

particularly markets as complex as India and China, is awareness of<br />

the regulatory regime. This may be the biggest benefit in partnering<br />

with a local company that is more adept and up-to-date with the<br />

increasingly changing regulatory landscape in these markets.<br />

Ernst & Young: In the current climate, many Western companies<br />

need new models for raising capital creatively, tapping<br />

alternative sources of revenue and operating more efficiently.<br />

Given that Asian firms have often developed models different<br />

from the typical Western biotech model, what lessons, if any,<br />

could Western firms learn from their Asian counterparts?<br />

28 <strong>Beyond</strong> borders <strong>Global</strong> <strong>biotechnology</strong> <strong>report</strong> <strong>2010</strong><br />

Mazumdar-Shaw: Western biotechs tend to be dependent on a<br />

very high-risk, all-or-nothing business model funded by VC firms<br />

looking for timely returns on investment. This puts a lot of pressure<br />

on companies to find a path to an exit, because VCs have a limited<br />

investment horizon. Of course, if a drug candidate fails, the<br />

company is often finished unless it can find more funding to go on<br />

to something else.<br />

We can’t afford that sort of operating model in India, because risk<br />

capital is largely unavailable for Indian biotech companies. Our<br />

businesses are mostly debt-funded. A bank isn’t looking for a VCstyle<br />

“exit” — it simply wants you to pay back your loan by managing<br />

risk well and building a sustainable, profitable business. Companies<br />

like Biocon are self-funded — we use revenues from our product<br />

and services to fund our R&D pipeline. So Indian companies have to<br />

carefully manage risk in making R&D choices and determining their<br />

business mix. For Western biotechs, the lesson may be in how you<br />

approach your business model — are you building an investment<br />

opportunity or building a sustainable business?<br />

Jiang: The “standard” biotech business model has served Western<br />

patients and economies wonderfully for decades. Now, we need<br />

to serve the needs of patients in emerging markets. And to do<br />

that, we need new thinking and new business models. Of course,<br />

Western companies should preserve good corporate principles and<br />

bring them to emerging markets, including quality, ethics and legal<br />

protections. But the biggest mistake they could make is coming in<br />

with preconceived notions and doing everything “as usual.”<br />

In the area of talent, for instance, one mistake multinationals<br />

can make is to not fully appreciate and utilize the potential of<br />

local talent. There is always an adjustment period during which<br />

“The ‘standard’ biotech business model has<br />

served Western patients and economies<br />

wonderfully for decades. Now, we need to<br />

serve the needs of patients in emerging<br />

markets. And to do that, we need new<br />

thinking and new business models.”

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