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A SYSTEMATIC REVIEW OF THE EFFECTS OF PSYCHOTHERAPY ...

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Table 2.1 GRADE System for Evaluating Evidence<br />

Criteria for GRADE*<br />

Type of evidence:<br />

High (randomized, controlled trial)<br />

Low (observational study)<br />

Very low (any other evidence)<br />

Decrease grade if:<br />

Serious ( -1) or very serious ( -2) limitation to study quality<br />

Important inconsistency ( -1)<br />

Some ( -1) or major ( -2) uncertainty about directness<br />

Imprecise or sparse data ( -1)<br />

High probability of reporting bias ( -1)<br />

Increase grade if:<br />

Strong evidence of association-significant relative risk of >2 (p < .5) based on consistent evidence<br />

From > observational studies, with no plausible confounders ( +1)<br />

Very strong evidence of association-significant relative risk of >2 (p < .2) based on direct<br />

evidence with no major threats to validity ( +2)<br />

Evidence of dose response gradient ( +1)<br />

All plausible confounders would have reduced effect ( +1)<br />

Ratings:<br />

High<br />

Moderate<br />

Low<br />

Very low<br />

*GRADE indicates Grading of Recommendations, Assessment, Development, Evaluation<br />

(GRADE WORKING GROUP, 2006)<br />

2.1.4 Data Synthesis<br />

Only in the past few years has methodologically rigorous evidence begun to emerge in the<br />

field of equine-facilitated/assisted psychotherapy and to date no randomized clinical trials, considered<br />

the gold standard in research methodology, have been conducted. Due to the heterogeneity of the<br />

study populations, psychometric instruments, and interventions included in this review, quantitative<br />

analyses could not be performed. However, qualitative methods were employed to classify<br />

interventions as having positive, negative, or no effect as determined by whether significant differences<br />

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