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Self Instructional Manual for Cancer Registrars - SEER - National ...

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Other Laboratory Studies<br />

Marrow Acid Phosphatase. Accurate staging of prostatic cancer is important <strong>for</strong><br />

determining treatment. Since the skeletal survey by routine radiography may be negative<br />

until approximately 40 percent of bone is involved with tumor, other tests, including marrow<br />

acid phosphatase, are used <strong>for</strong> the detection of early bone metastasis in patients with<br />

prostatic cancer. An elevated bone marrow acid phosphatase follows dissemination of<br />

prostatic cancer to the marrow space and contraindicates radical surgery in these patients.<br />

Normal values <strong>for</strong> marrow acid phosphatase are the same as <strong>for</strong> serum acid phosphatase.<br />

Hormonal Studies. Certain malignancies are quite apt to change the level of<br />

hormones and/or steroids produced in the body. A study of the hormone/steroid<br />

composition of the urine can sometimes be used to infer the presence of such a malignancy.<br />

There will not be many instances when you will have to abstract a report of a hormone<br />

or steroid study. Hormone studies may be used as an aid in diagnosing tumors of the<br />

adrenal cortex, pancreas, uterus, and testes.<br />

117

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