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Self Instructional Manual for Cancer Registrars - SEER - National ...

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CYTOLOGY<br />

AND ITS PROCEDURES<br />

Cytology is the study of the structure and function of cells; the examination of cells under a<br />

microscope as used in the diagnosis of cancer.<br />

There are a variety of procedures employed to obtain material <strong>for</strong> cytologic examination from fine<br />

needle aspiration of superficial or internal lesions to exfoliated cells obtained by aspiration, washing,<br />

brushing, smears, or scraping of vaginal secretions, sputum, urine, abdominal fluid, prostate secretions,<br />

etc. The more common techniques include:<br />

Brushings--the procedure of brushing the lining of an organ <strong>for</strong> the purpose of obtaining cells<br />

Punctures--Inserting a hollow needle into a cavity or organ <strong>for</strong> the purpose of removal of some<br />

portion of the contents (fluid, bone marrow, tissue)<br />

Paracentesis--Surgical puncture of a cavity <strong>for</strong> aspiration of fluid, such as the abdominal cavity<br />

Thoracentesis--Surgical puncture <strong>for</strong> aspiration of fluid from the chest<br />

Scrapings--the procedure of scraping the lining of a structure with an instrument <strong>for</strong> the purpose<br />

of obtaining cells<br />

Swabs--Using a swab or similar device to obtain fluid and secretions which then can be used to<br />

make a smear<br />

Washings--the removal of fluid from a hollow organ or structure <strong>for</strong> the purpose of collecting any<br />

cells in the fluid which may have exfoliated<br />

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