Self Instructional Manual for Cancer Registrars - SEER - National ...

EXAMPLE
G5 (continued)
MICROSCOPIC:
Microscopically there is a ragged ulcer penetrating to within 5 mm of the serosal surface.
The ulcer is surrounded by dense connective response and chronic inflammatory infiltrate.
The edges are not helped up, but several sections of the ulcer reveal malignant changes.
The tumor is superficial and composed of poorly formed glands and sheets of malignant
cells. The ceils are pleomorphic with small amounts of eosinophilic cytoplasm. The nuclei
are either pyknotic or large with prominent nucleoli and clumped chromatin. Mitoses are
rare. The tumor proper does not extend below the mueosa, but a single nest of malignant
cells is seen in a submucosal lymphatic space. The surgical margins are free of tumor.
Four perigastric lymph nodes show no evidence of metastatic spread.
There are two segments of large peripheral nerve.
DIAGNOSIS:
1. Superficial spreading carcinoma rising in the margin of a chronic gastric ulcer - the
surgical margins appear free of tumor.
2. Perigastric lymph nodes (4) without demonstrable metastases.
Tish Ewing, MD
Pathologist
Name Marie du Malade Reg. No. 000041
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