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Self Instructional Manual for Cancer Registrars - SEER - National ...

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EXAMPLE<br />

G4 (continued)<br />

left radical neck dissection which bordered upon the anterior aspect of the vertebral column.<br />

A fragment of tissue is excised from this area and submitted <strong>for</strong> sectioning labeled "VM."<br />

After having been photographed in several positions, the specimen is blocked further. A<br />

section is taken through the main tumor mass and submitted <strong>for</strong> sectioning labeled _I'<br />

POST." Attention is directed to the left radical neck dissection proper. This part of the<br />

specimen is divided into the appropriate five levels. Each level is examined <strong>for</strong> lymph nodes<br />

which are dissected free and submitted in their entirety <strong>for</strong> sectioning. The remainder of<br />

the specimen is saved.<br />

Part #3 of the specimen, labeled "anterior margin of inferior mandible" consists of an<br />

irregular fragment of fibrous connective and skeletal muscular tissues and measures<br />

approximately 1.0 x 0.5 x 0.2 cm. The specimen is submitted in its entirety <strong>for</strong> sectioning<br />

on three levels.<br />

MICROSCOPIC<br />

DESCRIPTION:<br />

Microscopic examination of frozen section control #1 confirms the original frozen section<br />

diagnosis of "ganglion."<br />

Microscopic examination of frozen section control #2 confirms the original frozen section<br />

diagnosis of "no tumor seen."<br />

Microscopic examination of frozen section control #3 confirms the original frozen section<br />

diagnosis of "no tumor seen."<br />

Microscopic examination of part #2 of the specimen reveals foei of moderately well<br />

differentiated squamous cell carcinoma in the floor of the left side of the mouth. The<br />

residual tumor is surrounded by large amounts of dense fibrous connective tissue.<br />

Microscopic examination of the section labeled CM which represents the carotid margin<br />

reveals squamous cell carcinoma extending to within 0.1 cm of the surgical margin.<br />

Microscopic examination of section labeled VM representing the vertebral margin fails to<br />

reveal evidence of tumor in this location. Microscopic examination of the tissue in level I<br />

reveals section of fibrotic and atrophic submaxillary salivary gland. There is also one lymph<br />

node in level I which is negative <strong>for</strong> metastatic tumor. Microscopic examination of the<br />

tissue in level II reveals sections of 11 lymph nodes none of which contains metastatic<br />

tumor. However, the extranodal fibrous connective tissue in level III contains numerous<br />

loci of squamous cell carcinoma. Microscopic examination of the tissue in level IV reveals<br />

sections of 6 lymh nodes, none of which contains metastatic tumor. Microscopic<br />

examination of the tissue in level V reveals 1 lymph node which is negative <strong>for</strong> metastatic<br />

tumor.<br />

Name Phineas Feltbad Reg. No. 000040<br />

Continued on next page<br />

208

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