Welcome to the 31st IUBS General Assembly and Conference on ...

that <strong>the</strong> regulation of water by TGR has had a remarkable
influence on <strong>the</strong> structure of rodent communities on <strong>the</strong>
beach.Apodemus agrarias, for example, seldom inhabited
on <strong>the</strong> beach before TGP, is now found universally on <strong>the</strong>
beach <strong>and</strong> <strong>the</strong> population is growing. Meanwhile, it is
known that Yantze voles (Microtus fortis) was <strong>the</strong> only
absolutely dominant species on <strong>the</strong> beach, <strong>and</strong> its
development is closely related <strong>to</strong> evolvement of lake
beaches surrounding Dongting Lake. The population of
<strong>the</strong> voles may increase fur<strong>the</strong>r because of <strong>the</strong> lower water
level <strong>and</strong> more emerging time during rainy season as a
result of dispatching down flow rate after TGP. Therefore,
we should pay more attention <strong>to</strong> <strong>the</strong> population
fuctuation of A. agrarias <strong>and</strong> M. fortis, as well as <strong>the</strong>
succession of rodent communitieson <strong>the</strong> beach areas of
Dongting Lake.
The complete mi<strong>to</strong>chondrial genome of
Lasiopodomys m<strong>and</strong>arinus (Arvicolinae,
Rodentia) <strong>and</strong> its phylogenetic analysis
Zhenlong WANG
Zhengzhou University, No.100 Kexue Road, Gaoxin District,
Zhengzhou, Henan, China. Email: zhenlong.wang1@gmail.com
The m<strong>and</strong>arin vole (Lasiopodomysm<strong>and</strong>arinus,
Milne‐Edwards, 1871) is a subterranean rodent that
widely distributed in nor<strong>the</strong>ast <strong>and</strong> central China, north
central Mongolia <strong>and</strong> adjacent part of Siberia south of
Lake Baikal <strong>and</strong> <strong>the</strong> sou<strong>the</strong>rn <strong>and</strong> central Korean
Peninsula. The m<strong>and</strong>arin vole is a labora<strong>to</strong>ry animal
model using in <strong>the</strong> study about subterranean hypoxic
stress on mammals. By using long‐PCR, we determined
<strong>the</strong> complete mi<strong>to</strong>chondrial (MT) genome of L.
m<strong>and</strong>arinus. Our results showed that <strong>the</strong> mi<strong>to</strong>chondrial
genome of L. m<strong>and</strong>arinus was a circular molecule 16
367bp, <strong>and</strong> had a typical gene content of 13 protein
coding, 22 tRNAs <strong>and</strong> 2 rRNAs genes. Except for <strong>the</strong> 8
tRNA <strong>and</strong> ND6 genes, all o<strong>the</strong>r MT genes are encoded on
<strong>the</strong> heavy str<strong>and</strong>. We analyzed <strong>the</strong> phylogenetic position
of L.m<strong>and</strong>arinus within <strong>the</strong> Rodentia <strong>and</strong> o<strong>the</strong>r mammals
by using <strong>the</strong> sequence of 13 protein coding genes
connected <strong>to</strong>ge<strong>the</strong>r. Our phylogenetic study proved that L.
m<strong>and</strong>arinus was one of <strong>the</strong> subspecies of Lasiopodomys.
And <strong>the</strong> Lasiopodomys should be retained as a separated
genus of Arvicolinae. The phylogenetic analysis also gave
a fur<strong>the</strong>r evidence of Rodents monophyly.
The FUNG­GROWTH database: linking
growth <strong>to</strong> genome
Miaomiao ZHOU, 1 Wiebenga AD, 1 Robert
VINCENT, 1 Pedro M COUTINHO, 1 Ronaldde
VRIES 1 <strong>and</strong> BernardHENRISSAT 2
1Centre of Fungal Biodiversity, KNAW<strong>and</strong> 2 AFMB, Marseille,
France. Email: m.zhou@cbs.knaw.nl
Aspergillus genome sequences demonstrate <strong>the</strong> potential
<strong>to</strong> utilize a variety of different carbon sources. Natural
carbon sources for many fungi are based on plant
biomass <strong>and</strong> often consist of polymeric compounds, such
as polysaccharides. They cannot be taken up by <strong>the</strong> fungal
cell <strong>and</strong> are extracellularly degraded by a complex mixture
of enzymes. Plant polysaccharide degrading enzymes
have been studied for decades due <strong>to</strong> <strong>the</strong>ir applications in
food <strong>and</strong> feed, paper <strong>and</strong> pulp, beverages, detergents,
textile <strong>and</strong> biofuels. These enzymes have been classified
based on amino acid sequence modules (www.cazy.org).
Based on <strong>the</strong> hypo<strong>the</strong>sis that Aspergillus genomes have
evolved <strong>to</strong> suit <strong>the</strong>ir ecological niche, we have performed
a comparative study using 34 Aspergillus species/strains.
In this study we have compared growth profiles on 35
different carbon sources (consisting of mono‐, oligo‐ <strong>and</strong>
polysaccharides, lignin, protein <strong>and</strong> crude plant biomass)
<strong>to</strong> <strong>the</strong> CAZy annotation of <strong>the</strong> genomes <strong>to</strong> identify
correlations between growth <strong>and</strong> genomic potential.
Fur<strong>the</strong>r analysis involves comparative transcrip<strong>to</strong>mics
using various system biology strategies, focusing on
degradation related gene regula<strong>to</strong>rs.
Highlights of <strong>the</strong>se integrative bioinformatics analysis
will be presented as well as <strong>the</strong> public database in which
<strong>the</strong> growth data is s<strong>to</strong>red <strong>and</strong> <strong>the</strong> developments of <strong>the</strong>
database anticipated for <strong>the</strong> next two years.
The inhibi<strong>to</strong>ry mechanisms of heat shock
protein 90 inhibition on LPS­enhanced
inflamma<strong>to</strong>ry cy<strong>to</strong>kine <strong>and</strong> matrix
metalloproteinase­9 expression in human
monocytic cells
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