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Welcome to the 31st IUBS General Assembly and Conference on ...

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computati<strong>on</strong>al biology. Herein, we report <strong>on</strong> various<br />

efforts geared <str<strong>on</strong>g>to</str<strong>on</strong>g>wards designing a potential model as<br />

part of strategies for incorporating quantitative biology<br />

modules in<str<strong>on</strong>g>to</str<strong>on</strong>g> undergraduate life science. Some of <str<strong>on</strong>g>the</str<strong>on</strong>g>se<br />

include employing ma<str<strong>on</strong>g>the</str<strong>on</strong>g>matical methods underlying<br />

bioinformatics <str<strong>on</strong>g>and</str<strong>on</strong>g> computati<strong>on</strong>al biology <str<strong>on</strong>g>to</str<strong>on</strong>g>ols <str<strong>on</strong>g>and</str<strong>on</strong>g><br />

software applicati<strong>on</strong>s, as well as simple ma<str<strong>on</strong>g>the</str<strong>on</strong>g>matical<br />

algorithms that c<strong>on</strong>stitute <str<strong>on</strong>g>the</str<strong>on</strong>g> core of systems biology<br />

fundamental <str<strong>on</strong>g>to</str<strong>on</strong>g> underst<str<strong>on</strong>g>and</str<strong>on</strong>g>ing <str<strong>on</strong>g>the</str<strong>on</strong>g> pathophysiology of<br />

diseases.<br />

DNA barcoding technology: an <strong>on</strong>going<br />

molecular <str<strong>on</strong>g>to</str<strong>on</strong>g>ol for biological studies<br />

Nancai PEI<br />

using a resolved barcode phylogeny, ra<str<strong>on</strong>g>the</str<strong>on</strong>g>r than a<br />

poorly‐resolved phylogeny. The excellent performance<br />

of rapid identificati<strong>on</strong>, resolved‐phylogeny<br />

rec<strong>on</strong>structi<strong>on</strong> <str<strong>on</strong>g>and</str<strong>on</strong>g> powerful ecological interpretati<strong>on</strong><br />

indicate that DNA barcode technology is potentially<br />

qualified as an effective <str<strong>on</strong>g>to</str<strong>on</strong>g>ol for current biological<br />

studies.<br />

Early radiati<strong>on</strong> of Mollusca<br />

Pavel Yu PARKHAEV<br />

Borissiak Pale<strong>on</strong><str<strong>on</strong>g>to</str<strong>on</strong>g>logical Institute of <str<strong>on</strong>g>the</str<strong>on</strong>g> Russian Academy of<br />

Sciences, Profsoyuznaya 123, Moscow 117647, Russia. Email:<br />

pparkh@paleo.ru<br />

Research Institute of Tropical Forestry, Chinese Academy of<br />

Forestry, #682 Guangshan Road 1, Tianhe, Guangzhou 510520,<br />

China. Email: nan‐caipei@scib.ac.cn<br />

Molecular <str<strong>on</strong>g>to</str<strong>on</strong>g>ols play an important role when processing<br />

<str<strong>on</strong>g>the</str<strong>on</strong>g> data <str<strong>on</strong>g>and</str<strong>on</strong>g> obtaining results for biological studies. DNA<br />

barcoding, a kind of newly developed molecular<br />

technology, aims <str<strong>on</strong>g>to</str<strong>on</strong>g> discriminate biological species by<br />

utilizing a short universal gene sequence taken from a<br />

st<str<strong>on</strong>g>and</str<strong>on</strong>g>ardized porti<strong>on</strong> of <str<strong>on</strong>g>the</str<strong>on</strong>g> genome. Besides <str<strong>on</strong>g>the</str<strong>on</strong>g> ability of<br />

species’ correct identificati<strong>on</strong>, DNA barcoding can work<br />

as <str<strong>on</strong>g>the</str<strong>on</strong>g> founder <str<strong>on</strong>g>to</str<strong>on</strong>g> discover potentially new species,<br />

especially un‐described <str<strong>on</strong>g>and</str<strong>on</strong>g> cryptic species. Toge<str<strong>on</strong>g>the</str<strong>on</strong>g>r<br />

with traditi<strong>on</strong>al tax<strong>on</strong>omy, DNA barcoding, providing with<br />

a huge amount of molecular sequence data, emerges a<br />

modern discipline named integrative tax<strong>on</strong>omy. Based <strong>on</strong><br />

<str<strong>on</strong>g>the</str<strong>on</strong>g> DNA barcode sequence data, a resolved phylogeny can<br />

be obtained by adopting a combinati<strong>on</strong> comprising of<br />

genes with slow evolving rates (as <str<strong>on</strong>g>the</str<strong>on</strong>g> Anchor) <str<strong>on</strong>g>and</str<strong>on</strong>g> genes<br />

with fast evolving rate (as <str<strong>on</strong>g>the</str<strong>on</strong>g> Identifier). Fur<str<strong>on</strong>g>the</str<strong>on</strong>g>r,<br />

benefiting from <str<strong>on</strong>g>the</str<strong>on</strong>g> resolved phylogeny, phylogenetic<br />

diversity for biological communities across large spatial<br />

scales can be computed accurately than before.<br />

Better‐resolved phylogenies, based <strong>on</strong> a matrix of<br />

multi‐loci DNA barcodes, can increase <str<strong>on</strong>g>the</str<strong>on</strong>g> power when<br />

interpreting <str<strong>on</strong>g>the</str<strong>on</strong>g> observed patterns in <str<strong>on</strong>g>the</str<strong>on</strong>g> biological<br />

communities, <str<strong>on</strong>g>and</str<strong>on</strong>g> can decrease <str<strong>on</strong>g>the</str<strong>on</strong>g> probability of type II<br />

statistical errors often happened when a poorly‐resolved<br />

phylogeny present. Much previously published literature<br />

has detected significantly phylogenetic structure both in<br />

tropical forest plots <str<strong>on</strong>g>and</str<strong>on</strong>g> subtropical forest plots when<br />

The phylum Mollusca is <strong>on</strong>e of <str<strong>on</strong>g>the</str<strong>on</strong>g> largest metazoan<br />

group including approximately 130 000 nominal recent<br />

<str<strong>on</strong>g>and</str<strong>on</strong>g> 70 000 nominal extinct species. In additi<strong>on</strong> <str<strong>on</strong>g>to</str<strong>on</strong>g> <str<strong>on</strong>g>the</str<strong>on</strong>g><br />

high tax<strong>on</strong>omic diversity, molluscs are characterized by<br />

a number of different bauplans. Molluscs dwell in<br />

almost all types of habitats, occupying variable<br />

ecological niches in all range of marine <str<strong>on</strong>g>and</str<strong>on</strong>g> freshwater<br />

basins, <str<strong>on</strong>g>and</str<strong>on</strong>g> <strong>on</strong> <str<strong>on</strong>g>the</str<strong>on</strong>g> l<str<strong>on</strong>g>and</str<strong>on</strong>g>. Such diversity <str<strong>on</strong>g>and</str<strong>on</strong>g> ecological<br />

success of <str<strong>on</strong>g>the</str<strong>on</strong>g> phylum were achieved during <str<strong>on</strong>g>the</str<strong>on</strong>g> l<strong>on</strong>g<br />

evoluti<strong>on</strong>, lasting at least during <str<strong>on</strong>g>the</str<strong>on</strong>g> entire<br />

Phanerozoic.<br />

The earliest finds of undoubted molluscs come from<br />

<str<strong>on</strong>g>the</str<strong>on</strong>g> terminal Precambrian (uppermost<br />

Nemakin–Daldynian) – basal Cambrian (lowermost<br />

Tommotian). The Vendian soft‐bodied animal<br />

Kimberella, recently declared as molluscan ances<str<strong>on</strong>g>to</str<strong>on</strong>g>rs,<br />

has principle ethologic <str<strong>on</strong>g>and</str<strong>on</strong>g> structural differences,<br />

hence representing different animal phylum, but not<br />

Mollusca. Studies of ancient molluscs reveal important<br />

data for general <str<strong>on</strong>g>and</str<strong>on</strong>g> evoluti<strong>on</strong>ary malacology, shedding<br />

<str<strong>on</strong>g>the</str<strong>on</strong>g> light <strong>on</strong> <str<strong>on</strong>g>the</str<strong>on</strong>g> earliest diversificati<strong>on</strong> <str<strong>on</strong>g>and</str<strong>on</strong>g> evoluti<strong>on</strong> of<br />

major branches of <str<strong>on</strong>g>the</str<strong>on</strong>g> phylum. As a result, we can<br />

affirm <str<strong>on</strong>g>the</str<strong>on</strong>g> following peculiarities of <str<strong>on</strong>g>the</str<strong>on</strong>g> earliest<br />

molluscan radiati<strong>on</strong>:<br />

(1) The oldest representatives of phylum appear just<br />

below <str<strong>on</strong>g>the</str<strong>on</strong>g> Precambrian–Cambrian boundary. The<br />

classes M<strong>on</strong>oplacophora, Polyplacophora,<br />

Gastropoda, <str<strong>on</strong>g>and</str<strong>on</strong>g> Bivalvia have been formed already<br />

in <str<strong>on</strong>g>the</str<strong>on</strong>g> earliest Cambrian. O<str<strong>on</strong>g>the</str<strong>on</strong>g>r classes, Cephalopoda<br />

<str<strong>on</strong>g>and</str<strong>on</strong>g> Scaphopoda, have originated later, by <str<strong>on</strong>g>the</str<strong>on</strong>g> Late<br />

47

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