ICAS-PAT manual for Design of process monitoring and ... - CAPEC
ICAS-PAT manual for Design of process monitoring and ... - CAPEC
ICAS-PAT manual for Design of process monitoring and ... - CAPEC
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Appendix A: report generated in MS Word<br />
<strong>Design</strong> <strong>of</strong> <strong>process</strong> <strong>monitoring</strong> <strong>and</strong> analysis system (<strong>PAT</strong> system)<br />
Step1: Product quality specifications<br />
1. Specifications <strong>of</strong> Biomass Value Unit<br />
Composition 2.95 % (w/w)<br />
Concentration 30.00 g/l<br />
2. Specifications <strong>of</strong> Glucose Value Unit<br />
Composition 4.00 % (w/w)<br />
Concentration 40.69 g/l<br />
3. Specifications <strong>of</strong> Salts Value Unit<br />
Composition 0.58 % (w/w)<br />
Concentration 5.93 g/l<br />
4. Specifications <strong>of</strong> Water Value Unit<br />
Composition 92.46 % (w/w)<br />
Concentration 939.44 g/l<br />
Step2: Process specifications<br />
Equipment list<br />
Fermentor<br />
Sterilizer<br />
Mixing tank<br />
Raw material list<br />
Starter culture<br />
Glucose<br />
Salts<br />
Water<br />
Ammonia<br />
Air<br />
Step3: Process analysis<br />
Process points Process variables Lower limit Upper limit Unit<br />
Fermentor DO (Dissolved oxygen) 0.00067 0.007 Kg/m3<br />
Dissolved CO2 0.0005 0.004 Kg/m3<br />
pH 6 7<br />
Temperature 293 310 K<br />
Pressure 1 2 atm<br />
Inlet flow rate <strong>of</strong> air 0 10 m/s<br />
Outlet flow rate <strong>of</strong> air 0 10 m/s<br />
Inlet flow rate <strong>of</strong> NH3 0 10 m/s<br />
Outlet flow rate <strong>of</strong> NH3 0 10 m/s<br />
Substrate concentration 1 180 Kg/m3<br />
Biomass concentration 1 30 Kg/m3<br />
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