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IPDE - Extranet Systems - World Health Organization

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128 Manual<br />

section, if there are questions in that section that pertain to the disorders<br />

that are being assessed.<br />

The second option is to use the self-administered '<strong>IPDE</strong> Screening<br />

Questionnaire' to eliminate subjects who are unlikely to have a personality<br />

disorder or the particular disorders of interest. The screen is<br />

expected to produce a considerable number of false-positive but relatively<br />

few false-negative cases vis-a-vis the interview. The rates of<br />

case misidentification, however, are likely to vary considerably depending<br />

on the baserates of the disorders in the population in which it is<br />

employed.<br />

It is especially important to recognize that personality disorder questionnaires<br />

and semistructured clinical interviews are not interchangeable.8<br />

Therefore, under no circumstances should the '<strong>IPDE</strong> Screening<br />

Questionnaire' be used to make a psychiatric diagnosis. Nor should it be<br />

used to calculate dimensional scores, with the expectation that they will<br />

be equivalent to those based on the <strong>IPDE</strong> itself.<br />

Reliability and validity of the <strong>IPDE</strong><br />

The interrater agreement and temporal stability of the <strong>IPDE</strong> were studied<br />

at 14 clinical facilities in 11 countries in North America, Europe, Africa,<br />

and Asia. The field trial employed 58 psychiatrists and clinical psychologists<br />

as interviewers and observers of 716 patients. The reliability and<br />

stability of the <strong>IPDE</strong> were roughly similar to what has been reported with<br />

instruments used to diagnose the psychoses, mood, anxiety, and substance<br />

use disorders?<br />

Establishing the validity of semistructured clinical interviews has<br />

proved to be a more elusive undertaking, because of the absence of an<br />

acceptable gold standard. The use of clinical consensus as that standard<br />

is problematic without information about the reliability and validity of<br />

the clinicians themselves. The advantage of semistructured interviews<br />

like the <strong>IPDE</strong>, is that they have a certain procedural validity that makes<br />

their conclusions more readily exportable, and less susceptible to institutional<br />

and regional biases. In theory, they provide clinicians and investigators<br />

with a more uniform method of case identification, and thus<br />

facilitate the comparison and replication of research findings. It was the<br />

opinion of most of the clinicians who participated in the field trial, that<br />

the <strong>IPDE</strong> was a useful and essentially valid method of assessing personality<br />

disorders for research purposes.

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