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Summary of Research Findings

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<strong>Research</strong> on Reduction <strong>of</strong> Chemical Toxicity (continued)<br />

2. Title<br />

In Vitro and In Vivo Inhibition <strong>of</strong> Microsomal Lipid Peroxidation by MA-631<br />

Publication<br />

Pharmacology, Biochemistry and Behavior, Vol. 48, No. 2, pp. 505-510, 1994.<br />

Authors<br />

Atef N. Hanna, Hari M. Sharma, Ellen M. Kauffman, and Howard A.I. Newman.<br />

Conducted at<br />

Department <strong>of</strong> Pathology, College <strong>of</strong> Medicine, The Ohio State University, Columbus, OH<br />

<strong>Summary</strong><br />

MA-631 is an herbal mixture from the comprehensive system <strong>of</strong> natural health care known as Maharishi<br />

Ayur-Veda. The in vivo portion <strong>of</strong> this study on MA-631 involved feeding rats a 2% (w:w) MA-631-supplemented<br />

diet for three weeks, then challenging their system with an intraperitoneal injection <strong>of</strong> toluene. The results<br />

showed that the 2% MA-631-supplemented diet completely inhibited the in vivo microsomal lipid peroxidation<br />

induced by toluene in rat brain, kidney, liver, and heart (p

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