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Summary of Research Findings

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<strong>Research</strong> on the Transcendental Meditation ® Program (continued)<br />

3. Title<br />

Usefulness <strong>of</strong> the Transcendental Meditation Program in the Treatment <strong>of</strong> Patients With<br />

Coronary Artery Disease<br />

Publication<br />

The American Journal <strong>of</strong> Cardiology, Vol. 77, pp. 867-870, 1996.<br />

Authors<br />

John W. Zamarra, MD, Robert H. Schneider, MD, Italo Besseghini, MD, Donald K. Robinson, MS, and John W.<br />

Salerno, PhD.<br />

Conducted at<br />

The Department <strong>of</strong> Medicine, State University <strong>of</strong> New York, Buffalo, NY; Veterans Administration Hospital,<br />

Buffalo, NY; and the Center for Health and Aging Studies, Maharishi University <strong>of</strong> Management, Fairfield, IA<br />

<strong>Summary</strong><br />

This investigation was designed as a pilot study to test the hypothesis that stress reduction intervention<br />

with the Transcendental Meditation (TM) program would reduce exercise-induced myocardial ischemia in<br />

patients with known coronary artery disease. Twenty-one patients with documented coronary artery disease<br />

were prospectively studied. After baseline symptom-limited exercise tolerance testing, subjects were assigned<br />

to practice the TM technique or allocated to a wait-list control group. Single blind testing was repeated after an<br />

average 7.6 months <strong>of</strong> follow-up. Results showed that the patients who learned TM demonstrated significantly<br />

greater exercise tolerance, higher maximal workload, delayed onset <strong>of</strong><br />

ST-segment depression, and decreases in double product at each exercise interval, compared with the control<br />

group. The reliability <strong>of</strong> the test data for assessing changes in exercise performance was supported by the<br />

relatively high reproducibility <strong>of</strong> the symptom-limited exercise tolerance test measures at baseline. The results<br />

suggest that practice <strong>of</strong> the Transcendental Meditation program is useful in reducing exercise-induced myocardial<br />

ischemia in patients with coronary artery disease and may be considered beneficial for the prevention and<br />

treatment <strong>of</strong> coronary artery disease.<br />

Reprinted by permission <strong>of</strong> the publisher from The American Journal <strong>of</strong> Cardiology, Vol. 77, 867-870. Copyright 1996<br />

by Excerpta Medica, Inc.<br />

Study 3 <strong>Research</strong> Highlights<br />

Human study results suggest that the Transcendental Meditation program is useful in reducing exerciseinduced<br />

myocardial ischemia in patients with coronary artery disease and may be considered beneficial for<br />

the prevention and treatment <strong>of</strong> coronary artery disease.<br />

89

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