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Summary of Research Findings

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Cancer <strong>Research</strong> (continued)<br />

2. Title<br />

Antineoplastic Properties <strong>of</strong> Maharishi Amrit Kalash [MAK-5], An Ayurvedic Food Supplement, Against 7,12-<br />

Dimethylbenz(a)anthracene-Induced Mammary Tumors in Rats<br />

Publication<br />

Journal <strong>of</strong> <strong>Research</strong> and Education in Indian Medicine, Vol. 10, No. 3, pp. 1-8, July-September 1991.<br />

Authors<br />

Hari M. Sharma,* Chandradhar Dwivedi,** Bryan C. Satter,** and Hussein Abou-Issa.*<br />

Conducted at<br />

**College <strong>of</strong> Medicine, The Ohio State University, Columbus, OH 43210<br />

**College <strong>of</strong> Pharmacy, South Dakota State University, Brookings, SD 57007<br />

<strong>Summary</strong><br />

The herbal mixture Maharishi Amrit Kalash-5<br />

(MAK-5) was tested for antineoplastic properties<br />

against 7,12-dimethylbenz(a)anthracene (DMBA)-<br />

induced mammary tumors in rats. The 0.2%<br />

(w/w) MAK-5-supplemented diet protected<br />

against DMBA-induced carcinogenesis during<br />

the promotion phase by reducing both tumor<br />

incidence and multiplicity. MAK-5 provided<br />

up to 62.5% protection (p

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