Summary of Research Findings
Summary of Research Findings
Summary of Research Findings
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<strong>Research</strong> on Anti-Aging, Neurophysiology and Intelligence (continued)<br />
8. Title<br />
Maharishi Amrit Kalash [MAK-4 and MAK-5] Rejuvenates Ageing Central Nervous System’s Antioxidant Defense<br />
System: An In Vivo Study<br />
Publication<br />
Pharmacological <strong>Research</strong>, Vol. 40, No. 6, pp 497-502, 1999.<br />
Authors<br />
Bhupinder Pal Singh Vohra,* Satya Prakash Sharma,* and Vinod Kumar Kansal.**<br />
Conducted at<br />
**Laboratory <strong>of</strong> Nutritional Histopathology and Ageing, Department <strong>of</strong> Zoology, Kurukshetra University,<br />
Kurukshetra—136 119, Haryana, India<br />
**Animal Biochemistry Division, National Dairy <strong>Research</strong> Institute, Karnal, Haryana, India<br />
<strong>Summary</strong><br />
The oxygen-free radical involvement in various deteriorative processes and in aging is unquestionably<br />
established. In the present study, age-related changes in antioxidant enzyme activity in the different regions <strong>of</strong><br />
CNS <strong>of</strong> 10-month and 32-month-old guinea pigs were studied. Maharishi Amrit Kalash has shown promise in<br />
inhibiting the in vitro and in vivo lipid peroxidation. Therefore, in the present study the effect <strong>of</strong> MAK on the<br />
activity <strong>of</strong> antioxidant enzymes was checked. Our results indicate that the activity <strong>of</strong> superoxide dismutase and<br />
glutathione peroxidase, was found to be reduced p