(log ppb) HPRT VF (x 10
(log ppb) HPRT VF (x 10
(log ppb) HPRT VF (x 10
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Cytochrom P450<br />
• Cytochrome P450 2A6<br />
• Microsomal (endoplasmic reticulum)<br />
• Biotransforms Coumarin<br />
O O HO<br />
O O<br />
CYP2A6<br />
Coumarin 7-hydroxycoumarin
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