(log ppb) HPRT VF (x 10
(log ppb) HPRT VF (x 10
(log ppb) HPRT VF (x 10
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CYP and DNA Damage<br />
• EROD Activity (Oxidative dealkylation)<br />
• 7-ethoxyresorufin → Resorufin<br />
• Indirect measure of CYP1A2 activity<br />
• DNA damage<br />
• Measured using DNA content estimates<br />
EROD activity correlates with DNA damage<br />
What do you conclude?
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