(log ppb) HPRT VF (x 10
(log ppb) HPRT VF (x 10
(log ppb) HPRT VF (x 10
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• “Phase III”<br />
biotransformation is<br />
the last part of the<br />
metabolism and<br />
disposition of<br />
pharmaco<strong>log</strong>ically<br />
active molecules<br />
• Comprised of export<br />
enzymes which<br />
consume ATP/GTP to<br />
transport various<br />
conjugates across<br />
membranes<br />
EXPORT (Phase 3)
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