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ANNUAL REPORT 2012 - TiGenix

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which have taken place in breach of these<br />

provisions if the counterparty to the decision<br />

or the transaction was, or should have been,<br />

aware of such breach.<br />

The procedure does not apply to decisions<br />

or transactions in the ordinary course of<br />

business at customary market conditions.<br />

It also does not apply to transactions or<br />

decisions between companies of which<br />

one holds (directly or indirectly) at least<br />

95 % of the voting financial instruments of<br />

the other, and transactions or decisions<br />

between companies whereby at least 95 %<br />

of the voting financial instruments of both<br />

companies are (directly or indirectly) held by<br />

another company.<br />

Article 524ter of the Companies Code<br />

provides for a similar procedure in the event<br />

of conflicts of interest of executive committee<br />

members. In the event of such conflict, only<br />

the Board of Directors will be authorized<br />

to take the decision that has led to the<br />

conflict of interest. The Company’s executive<br />

management team does not qualify as an<br />

executive committee in the sense of Article<br />

524bis of the Companies Code.<br />

Currently, the directors do not have a conflict<br />

of interest within the meaning of Article 523<br />

of the Companies Code that has not been<br />

disclosed to the Board of Directors.<br />

7.9.3. Related party transactions<br />

Article 524 of the Companies Code provides<br />

for a special procedure that applies to<br />

intra-group or related party transactions<br />

with affiliates. The procedure applies to<br />

decisions or transactions between the<br />

Company and affiliates of the Company<br />

that are not a subsidiary of the Company.<br />

It also applies to decisions or transactions<br />

between any of the Company’s subsidiaries<br />

and such subsidiaries’ affiliates that are not<br />

a subsidiary of the Company. Prior to any<br />

such decision or transaction, the Board of<br />

Directors must appoint a special committee<br />

consisting of three independent directors,<br />

assisted by one or more independent<br />

experts. This committee must assess the<br />

business advantages and disadvantages<br />

of the decision or transaction for the<br />

Company. It must quantify the financial<br />

consequences thereof and must determine<br />

whether or not the decision or transaction<br />

causes a disadvantage to the Company<br />

that is manifestly illegitimate in view of<br />

the Company’s policy. If the committee<br />

determines that the decision or transaction<br />

is not manifestly illegitimate, but is of the<br />

opinion that it will prejudice the Company,<br />

it must clarify which advantages are taken<br />

into account in the decision or transaction<br />

to compensate the disadvantages. All these<br />

elements must be set out in the committee’s<br />

advice. The Board of Directors must then take<br />

a decision, taking into account the opinion<br />

of the committee.<br />

Any deviation from the committee’s advice<br />

must be motivated. Directors who have<br />

a conflict of interest are not entitled to<br />

participate in the deliberation and vote<br />

(as set out in section 7.9.2 above). The<br />

committee’s advice and the decision of<br />

the Board of Directors must be notified to<br />

the Company’s statutory auditor, who must<br />

render a separate opinion. The conclusion of<br />

the committee, an excerpt from the minutes<br />

of the Board of Directors and the opinion<br />

by the statutory auditor must be included in<br />

the (statutory) annual report of the Board of<br />

Directors.<br />

The procedure does not apply to decisions<br />

or transactions in the ordinary course of<br />

100 <strong>TiGenix</strong> I annual report <strong>2012</strong>

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