ANNUAL REPORT 2012 - TiGenix

- “Marker genes for use in the identification
of chondrocyte phenotypic stability and
in the screening of factors influencing
cartilage production” (PCT Publication
number WO2008/061804) : a patent family
of pending patents in the US, EP, AU, CA,
CN, HK, IN, IL, JP, NO, RU & SG; granted in
NZ. This patent family protects a biomarker
panel for chondrocyte development.
eASC technology improvements :
- “Compositions comprising adipose
stem cells” (PCT Publication number
WO/2010/070141) : a patent family of
EP, US & JP applications protecting
microencapsulated adipose derived
stem cells and their use in therapeutic
applications.
Cell therapy delivery patents :
- “Injection Device” (PCT Publication number
WO/2009/141727) : a patent family of EP, US
& JP applications protecting an injection
device of use in the administration of
cellular therapies.
- “Methods and compositions for use in
cellular therapies.” (PCT Publication number
WO/2009/141727) : a patent family of BR, CA,
MX, SG, US, CN, JP, IL, KR, AU, IN, NZ, RU &
EP applications protecting novel methods
for the intralymphatic administration of
cellular therapies, cell composition, kits and
therapeutic uses including in the treatment
of autoimmune and inflammatory disorders.
- “Cells, nucleic acid constructs, cells
comprising said constructs and methods
utilizing said cells in the treatment of
diseases.“(PCT Publication number
WO/2010/052313) : a patent family of AU,
CA, KR, EP, US & JP applications protecting
a genetically engineered adipose
derived stem cell, nucleic acid expression
constructs, methods for the preparation
thereof, kits and uses of the cells in the
preparation of regulatory T-cells and in the
therapy of diseases.
- “Stem cell culture media and methods.”
(PCT Publication number WO/2012/032112) :
a PCT application that protects a culture
medium and cell culture methods.
- “Methods and compositions for use in
cellular therapies.“ (PCT Publication number
WO/2012/095743) : a PCT application
protecting novel compositions, dosage and
dosage regimens for the intralymphatic
administration of cellular therapies, cell
composition, kits and therapeutic uses
including the treatment of autoimmune and
inflammatory disorders.
- “Biopsy Device” (PCT Publication number
WO/2010/092100) : a patent family of AU,
CA, CN, EA, IL, IN, EP, US & JP applications
protecting a device suitable for taking
cartilage biopsies.
- “Cell populations having immunoregulatory
activity, methods for the preparation and
uses thereof.” (PCT Publication number
WO/2012/123401) : a PCT application
protecting a population of adipose derived
stem cells as characterized by cell surface
markers. The application also claims
methods for the preparation of said cell
populations as well as kits, therapeutic
applications and the use of said cell
populations in the preparation of regulatory
T-cells.
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