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ANNUAL REPORT 2012 - TiGenix

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(25) Business combination<br />

Description of the business combination<br />

Effective as of May 3, 2011, the former<br />

shareholders of Cellerix SA (now <strong>TiGenix</strong><br />

SAU) contributed all their Cellerix shares<br />

into <strong>TiGenix</strong> NV, in exchange for <strong>TiGenix</strong> NV<br />

shares. Therefore, since the contribution,<br />

<strong>TiGenix</strong> owns all the shares of Cellerix, while<br />

the former Cellerix shareholders received<br />

<strong>TiGenix</strong> shares in exchange. At the closing<br />

of the transaction, Cellerix had a solid<br />

and outstanding investor base including<br />

specialized European healthcare funds<br />

(Ysios, LSP and Ventech), pharma corporate<br />

investment funds (Roche Venture Fund and<br />

Novartis Venture Fund), and Spanish private<br />

and institutional investors which became<br />

shareholders of <strong>TiGenix</strong>.<br />

Through the acquisition of Cellerix, <strong>TiGenix</strong><br />

has been able to further strengthen its<br />

leadership profile through the creation of<br />

the first stem cells group with a commercial<br />

offering and a strong product development<br />

pipeline.<br />

Following the acquisition by <strong>TiGenix</strong>, Cellerix<br />

was renamed <strong>TiGenix</strong> SAU. The team and<br />

facilities have been completely integrated<br />

into the <strong>TiGenix</strong> organization.<br />

<strong>TiGenix</strong> SAU is a Spanish cell therapy<br />

company that was founded in 2004. The<br />

company has a clinical stage pipeline<br />

of cell-based products for indications of<br />

inflammatory and autoimmune origin.<br />

The products are based on <strong>TiGenix</strong> SAU’s<br />

proprietary fat derived adult stem cell<br />

platform and represent a new generation of<br />

off-the-shelf cell therapy medicines. <strong>TiGenix</strong><br />

SAU’s stem cell platform and manufacturing<br />

capabilities have been fully validated<br />

according to EMA requirements.<br />

147

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