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ANNUAL REPORT 2012 - TiGenix

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Number of options Total Options issued in Options issued in<br />

Grant date 2010 2008<br />

Number of options created 221,508 420,718<br />

Weighted average exercise price (EURO) 0,01 5,29<br />

Fair value at grant date (EURO) 2,30 6,36<br />

Expiry date 30/09/16 30/09/16<br />

Balance at acquisiton date 642,226 221,508 420,718<br />

Granted 0 0 0<br />

Forfeited 0 0 0<br />

Exercised 0 0 0<br />

Expired 0 0 0<br />

Balance at December 31, 2011 642,226 221,508 420,718<br />

Granted 0 0 0<br />

Forfeited 0 0 0<br />

Exercised 0 0 0<br />

Expired 0 0 0<br />

Balance at December 31, <strong>2012</strong> 642,226 221,508 420,718<br />

Number of options Total Options issued in<br />

Grant date <strong>2012</strong> 2011 2010 2009 2008<br />

Number of options created 642,226 0 0 221,508 0 420,718<br />

Value of the vested options EBIP 2008 2,677,065 99,043 487,947 589,673 835,552 664,850<br />

Value of the vested options EBIP 2010 508,482 164,786 305,984 37,712 0 0<br />

Value of the options pending to be vested 0 0 0 0 0<br />

Forfeited 0 0 0 0 0<br />

Exercised 0 0 0 0 0<br />

Expired 0 0 0 0 0<br />

Balance at December 31, <strong>2012</strong> 3,185,547 263,829 793,931 627,385 835,552 664,850<br />

The fair value of each stock option is<br />

estimated on the date of grant using the<br />

Black Scholes model with the following<br />

assumptions :<br />

- The volatility of <strong>TiGenix</strong> SAU (determined at<br />

55 %).<br />

- Weighted average risk-free interests rates<br />

based on German Sovereign bond at the<br />

date of grant with a term equal to the<br />

expected life of the stock option, ranging<br />

between 0.85 % and 1.95 %.<br />

146 <strong>TiGenix</strong> I annual report <strong>2012</strong>

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