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European Journal of Medical Research - Deutsche AIDS ...

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30 EUROPEAN JOURNAL OF MEDICAL RESEARCH<br />

June 27, 2007<br />

Method <strong>of</strong> data collection will be a questionnaire filled out<br />

by doctors in Ukraine and Germany. A number <strong>of</strong> n = 100 in<br />

each country is seen to be powerful enough for significance <strong>of</strong><br />

conclusions. Questions will be e.g. First reported case <strong>of</strong> HIV<br />

in individual commemoration.<br />

Appraisal <strong>of</strong> effectiveness <strong>of</strong> present actions (peer education<br />

programs, safer sex campaigns, governmental approaches).<br />

Causes <strong>of</strong> escalation <strong>of</strong> HIV epidemic in Ukraine (financial<br />

lack, stigmata, cultural problem). Own socioeconomic<br />

evaluation and their impact on treatment <strong>of</strong> HIV/<strong>AIDS</strong> patients.<br />

Our expectation is the identification <strong>of</strong> reasons - besides the<br />

general problem <strong>of</strong> a weak health care system and political insecurity<br />

- why the HIV epidemic existing in Ukraine has such<br />

a severe course.<br />

A.11 (Poster)<br />

HIV und <strong>AIDS</strong> in der Ukraine - neuere<br />

Entwicklungen<br />

Alberth F. 1<br />

1 Connect plus e.V., Augsburg, Germany<br />

Ziele: Informationen über die epidemiolgische Entwicklung<br />

in der Ukraine<br />

Methodik: Präsentation<br />

Ergebnis: In der Ukraine und in der Russische Förderation<br />

steigen die Neuinfektionszahlen ständig an. Auch die „Bereinigung“<br />

der Statistik hilft wenig. (Momentan werden in der<br />

Statistik des Nationalen Aids-Zentrum nur noch die Menschen<br />

mit HIV und Aids erfasst, die sich beim Gesundheitssystem<br />

registrieren lassen und Kontakt zu den Kliniken<br />

oder Ärzten haben. Die antiretroviralen Medikamente sind<br />

vorhanden, erreichen jedoch nicht in ausreichendem Maße die<br />

Patienten, die dringend eine Therapie brauchen. Die Entwicklung<br />

in einem Hochprävalenzgebiet der Ukraine (Odessa) und<br />

in einem Niedrugprävalenzgebiet (Lemberg) werden<br />

dargestellt und die Reaktion des Staates und der NGO-Landschaft<br />

auf diese Herausforderung aufgezeigt.<br />

Verschiedene in- und ausländische Akteure entwickeln auf<br />

nationaler und lokaler Ebene Programme. Eine kurze Übersicht<br />

stellt den momentanen Stand dar.<br />

Schlussfolgerung: Connect plus arbeitet seit 6 Jahren in der<br />

Qualifizierung von medizinischem und sozial-psychologischen<br />

Fachkräften. Projekte, die auch modellhaft übertragen<br />

werden können werden vorgestellt.<br />

A.12 (Vortrag)<br />

KABaSTI-study results: Self reported incidence <strong>of</strong><br />

bacterial sexually transmitted infections (STIs) in<br />

German men who have sex with men (MSM) -<br />

influence <strong>of</strong> HIV serostatus and sexual risk taking<br />

Marcus U. 1 , Schmidt A.J. 1 , Hamouda O. 1<br />

1 Robert Koch-Institut, Infektionsepidemiologie, Berlin,<br />

Germany<br />

Objectives: An increase <strong>of</strong> STIs in MSM has been reported<br />

from many Western industrialised countries in recent years.<br />

Repeated behaviour surveys in MSM have demonstrated increasing<br />

numbers <strong>of</strong> sexual partners and declining use <strong>of</strong> condoms<br />

for anal intercourse. To better understand the reasons<br />

for increasing rates <strong>of</strong> STIs in MSM and to identify potential<br />

new approaches to STI prevention, a survey on knowledge,<br />

attitudes and behaviour as to STIs (KABaSTI-study) in MSM<br />

was conducted in 2006.<br />

Methods: Participants were recruited on German internet<br />

MSM contact sites (n=5,928) and country-wide through private<br />

medical practices (n=723) with a high proportion <strong>of</strong><br />

MSM clients. 6,833 completed questionnaires were analysed.<br />

Sexually transmitted infections diagnosed in the previous 12<br />

months were assessed.<br />

Results: From all responding participants (n=4,648), 5% each<br />

reported a diagnosis <strong>of</strong> syphilis or urethral gonorrhoea, and<br />

3,9% a diagnosis <strong>of</strong> Chlamydia infection. Incidence <strong>of</strong> these<br />

bacterial STIs (bSTI) was significantly higher in HIV positive<br />

(HIV+) compared to HIV negative (HIV-) or untested men, as<br />

well as in men who reported more than 10 compared to 10 or<br />

less partners (OR=4.9; 95%CI:4.0-5.9), and in men who reported<br />

5 or more episodes <strong>of</strong> unprotected anal intercourse<br />

(UAI) compared to less than 5 during the last 12 months<br />

(OR=7.3; 95%CI:5.9-9.1). HIV+ men without antiretroviral<br />

treatment (ART) reported higher incidences than HIV+ men<br />

receiving ART (OR=2.0; 95%CI:1.5-2.7). The highest incidences<br />

<strong>of</strong> bSTIs among HIV+ and HIV- men were reported by<br />

participants recruited through a bareback website. After controlling<br />

for number <strong>of</strong> partners and frequency <strong>of</strong> UAI, HIV+<br />

(OR=2.1; 95%CI:1.3-3.3) and HIV- (OR=2.4; 95%CI:1.5-3.9)<br />

men from bareback sites had higher risks <strong>of</strong> having been diagnosed<br />

with bSTIs than men recruited from other sites.<br />

Conclusions: Incidence <strong>of</strong> bSTIs is higher in HIV+ than in<br />

HIV- MSM. This can be explained by higher number <strong>of</strong> partners,<br />

more unprotected intercourse, less intention to use condoms<br />

for prevention <strong>of</strong> STIs, and formation <strong>of</strong> high risk sexual<br />

networks in which unprotected sex is common. Receiving<br />

ART may not only reduce the risk <strong>of</strong> further HIV transmission,<br />

but also the risk for acquisition <strong>of</strong> STIs by unknown<br />

mechanisms.<br />

Study supported by BMG<br />

A.13 (Poster)<br />

Highly variable use <strong>of</strong> diagnostic methods for<br />

sexually transmitted infections – results <strong>of</strong> a<br />

nationwide survey, Germany 2006<br />

Gilsdorf A. 1 , Hamouda O. 1 , Bremer V. 1<br />

1 Robert Koch-Institut, Abt. für Infektionsepidemiologie,<br />

Berlin, Germany<br />

Objective: Syphilis and HIV are the only notifiable sexually<br />

transmitted infections (STI) in Germany. Further data for STI<br />

are collected through a sentinel surveillance system. The use<br />

<strong>of</strong> diagnostic methods with high sensitivity and specificity are<br />

needed for high data quality and early detection. We asked<br />

sentinel and other physicians about the current use <strong>of</strong> diagnostic<br />

methods for STIs in order to recognise potential problems<br />

and provide recommendations.<br />

Methods: We performed a nationwide cross-sectional survey<br />

among randomly chosen physicians with a specialisation in<br />

gynaecology, urology and dermato-venerology (DV) as well<br />

as sentinel physicians. We asked physicians about the methods<br />

and the type <strong>of</strong> samples used to diagnose HIV, chlamydia<br />

(CT), gonorrhoea (GO) and syphilis (SY) and whether they<br />

would perform STI testing in asymptomatic patients. The results<br />

were stratified by medical speciality.<br />

Results: A total <strong>of</strong> 691/2228 (31.0%) physicians participated.<br />

80.1% participants <strong>of</strong>fered tests for HIV, 84.0% for CT,

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