13 th AnnUAL MEETing | Washington, DC USA May 19-22, 2010103Abstract DirectoryThursday, May 20, 2010Poster Session I — continued6:15 PM - 8:15 PMRoom: Exhibit Hall C & B-SouthLate Breaking Science I928Engineering Aptamers Against HIV-1 RT for Improved AntiviralBioactivityMargaret J. Lange, Angela S. Whately, Donald H. Burke929Directed Integration <strong>of</strong> New Insulated Lentiviral Vectors to theHeterochromatin towards Safer <strong>Gene</strong> Transfer to Stem <strong>Cell</strong>sAlexandre Artus, Caroline Duros, Yaïr Botbol, Simone Schultz, Manfred Schmidt, Christ<strong>of</strong>von Kalle, Marc Lavigne, Odile Y Cohen-Haguenauer930Genotoxic Potential <strong>of</strong> scAAV Vectors in Mouse LiverLucia E. Rosas, Kimberly Zaraspe, Douglas M. McCarty931In vivo Persistence <strong>of</strong> ex vivo Expanded CCR7+CD45RA+ T <strong>Cell</strong>sUsing a RetroNectin Stimulation MethodTatsuji Enoki, Nobuko Muraki, Akiko Kato, Mitsuko Ideno, Junichi Mineno932Self-inactivating ASLV Based Vectors for the <strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong> X-CGDKerstin B. Kaufmann, Julia Suerth, Christian Brendel, Axel Schambach, ChristopherBaum, Manuel GrezThursday, May 20 th
104<strong>American</strong> <strong>Society</strong> <strong>of</strong> <strong>Gene</strong> & <strong>Cell</strong> <strong>Therapy</strong>Abstract DirectoryFriday, May 21 stFriday, May 21, 2010Plenary Abstract Session 300Plenary Abstract Session8:00 AM - 10:00 AMRoom: Marriott Ballroom Salons 1, 2 & 3283 8:05 AMTherapeutic Transgene Expression in Patient-Specific iPS <strong>Cell</strong>s afterSelection <strong>of</strong> “Safe Harbors” for Lentiviral Vector IntegrationEirini P. Papapetrou, Gabsang Lee, Nirav Malani, Isabelle Riviere, Frederic D. Bushman,Lorenz Studer, Michel Sadelain.284 8:25 AMA Novel Lentiviral Expression System Reveals Patchwork ColonyFormation during Reprogramming to Induced Pluripotent Stem <strong>Cell</strong>sEva Warlich, Johannes Kuehle, Tobias Cantz, Martijn Brugman, Tobias Maetzig, MelanieGalla, Christine Völkel, Adam Filipczyk, Stephan Halle, Hannes Klump, Hans Schöler,Timm Schroeder, Christopher Baum, Axel Schambach.285 8:45 AMTargeted Genomic Modification and Inactivation <strong>of</strong> the CCR5 <strong>Gene</strong>Using PNA-Induced Homologous RecombinationErica B. Schleifman, Ranjit S. Bindra, Jean Leif, Nicole Ali McNeer, Jacob Del Campo,Faye Rogers, Pradeep Uchil, Leonard D. Shultz, W. Mark Saltzman, Priti Kumar, DaleGriener, Peter M. Glazer.286 9:05 AMDetermining the Specificity <strong>of</strong> Zinc Finger Nucleases by AnalyzingInsertion Site Distribution <strong>of</strong> Integrase Defective Lentiviral Vectors(IDLV) Trapped into DNA Double Strand BreaksRichard Gabriel, Angelo Lombardo, Anne Arens, Pietro Genovese, Michael C. Holmes,Philip D. Gregory, Manfred Schmidt, Luigi Naldini, Christ<strong>of</strong> von Kalle.287 9:25 AMSystemic Administration <strong>of</strong> Dendrimer- and Aptamer-siRNAConjugates Efficiently Suppresses HIV-1 InfectionJiehua Zhou, Preston C. Neff, Xiaoxuan Liu, Jane Zhang, Haitang Li, Piotr Swiderski, LingPeng, Ramesh Akkina, John J. Rossi.288 9:45 AMCASPALLO: Phase I Clinical Trial <strong>of</strong> Allodepleted T <strong>Cell</strong>s Transducedwith Inducible Caspase 9 Suicide <strong>Gene</strong> after Haploidentical Stem <strong>Cell</strong>TransplantationAntonio Di Stasi, Siok K. Tey, Yuriko Fujita, Russell Cruz, Caridad Martinez, AlanaKennedy-Nasser, George Carrum, Carlos A. Ramos, Stephen M. Gottschalk, KarinStraath<strong>of</strong>, Lin Yu-Feng, Enli Liu, April Durett, Bambi Grilley, Hao Liu, Barbara Savoldo,Eric Yvon, Teresita Lopez, Oumar Diouf, Deborah Lyon, Adrian Gee, Ellen Vitetta, JohnSchindler, Catherine M. Bollard, Robert A. Krance, David M. Spencer, Gianpietro Dotti,Cliona M. Rooney, Helen E. Heslop, Malcolm K. Brenner.Oral Abstract Session 320Clinical <strong>Gene</strong> & <strong>Cell</strong> <strong>Therapy</strong> Oral Abstract Session2:00 PM - 4:00 PMRoom: Marriott Ballroom Salons 2 & 3289 2:00 PMTherapeutic DNA Vaccination Followed by Standard-<strong>of</strong>-Care <strong>Therapy</strong>in Patients with Chronic Hepatitis C: A Rapid Clearance <strong>of</strong> ViremiaMatti Sallberg, Lars Frelin, Helmut M. Diepolder, Maria C. Jung, Iacob Mathiesen,Michael Fons, Gustaf Ahlen, Margaret Chen, Ola Weiland.290 2:15 PMSustained Alpha-Sarcoglycan <strong>Gene</strong> Expression in LGMD2D Following<strong>Gene</strong> TransferJerry R. Mendell, Louise R. Rodino-Klapac, Xiomara Rosales-Quintero, Brian D. Coley,Gloria Galloway, Sarah Lewis, Vinod Malik, Christopher J. Shilling, Barry J. Byrne,Thomas Conlon, Katherine J. Campbell, William G. Bremer, Christopher M. Walker, ZarifeSahenk, K. Reed Clark.291 2:30 PMAdvanced <strong>Gene</strong>ration RGD-Modified Oncolytic Adenovirus ICOVIR-7in the Treatment <strong>of</strong> Cancer Refractory to Other ModalitiesPetri Nokisalmi, Sari Pesonen, Sophie Escutenaire, Mari Raki, Vincenzo Cerullo, RamonAlemany, Juanjo Rojas, Maria Rajecki, Lotta Kangasniemi, Anna Kanerva, Timo Joensuu,Laura Ahtiainen, Akseli Hemminki.292 2:45 PMFinal Results <strong>of</strong> Phase I Trial <strong>of</strong> GMCSF <strong>Gene</strong>-TGFb2 Antisense <strong>Gene</strong>Autologous Tumor <strong>Cell</strong> (TAG) Vaccine in Advanced CancerJohn Nemunaitis, Padmasini Kumar, Neil Senzer, Joseph Kuhn, Minal Barve, JairoOlivares, Gerald Edelman, Cynthia Bedell, Yang Yu, Mitchell Magee, Beena O. Pappen,Gladice Wallraven, Alex W. Tong, Phillip B. Maples.293 3:00 PMAdministration <strong>of</strong> Tumor-Specific Cytotoxic T Lymphocytes Engineeredto Resist TGF-ß to Subjects with EBV-Associated LymphomasCatherine M. Bollard, Gianpietro Dotti, Stephen Gottschalk, Enli Liu, Andrea M. Sheehan,George Carrum, Hao Liu, Chung-Che Chang, Adrian P. Gee, Malcolm K. Brenner, Helen E.Heslop, Cliona M. Rooney.294 3:15 PMEfficient Engraftment <strong>of</strong> MGMTP140K <strong>Gene</strong>-Modified CD34+ <strong>Cell</strong>sFollowing Nonmyeloablative BCNU Conditioning in Patients withGlioblastomaJennifer E. Adair, Brian C. Beard, Alexander Spence, Jason Rockhill, Daniel L. Silbergeld,Robert Rostomily, Pamela Becker, Marc Chamberlain, Maciej Mrugala, Hans-Peter Kiem.295 3:30 PMThymic Renewal and Anti-Leukemic Effect in Adults afterHaplodentical Transplantation and Suicide <strong>Gene</strong> <strong>Therapy</strong>Luca Vago, Giacomo Oliveira, Maddalena Noviello, Corrado Soldati, Domenico Ghio,Roberto Nicoletti, Immacolata Brigida, Alessandro Aiuti, Maria Teresa Lupo Stanghellini,Jacopo Peccatori, Attilio Bondanza, Katharina Fleischhauer, Claudio Bordignon, FabioCiceri, Chiara Bonini.EXHIBITOR PROSPECTUSfinal program
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