FINAL PROGRAM - American Society of Gene & Cell Therapy

126American Society of Gene & Cell TherapyAbstract DirectorySaturday, May 22 ndSaturday, May 22, 2010Oral Abstract Session 430 — continuedAdenovirus and Other DNA Virus Vectors3:00 PM - 5:00 PMRoom: Maryland Suite642 4:30 PMThe Cytoplasmic Sensor, NOD2, Induces the Innate Immune Responseand Transgene Silencing of Vector after Systemic Administration ofHelper-Dependent AdenovirusMasataka Suzuki, Vincenzo Cerullo, Racel G. Cela, Terry K. Bertin, Christian Clarke, LeeH. Brendan.643 4:45 PMCAdVax-Vectored Multivalent Filovirus Vaccine Protects NHP AgainstChallenge at 1000 Times the Lethal Dose of Ebola and MarburgVirusesJohn Y. Dong, Danher Wang, William D. Pratt.Oral Abstract Session 431Infectious Diseases and Vaccines3:00 PM - 5:00 PMRoom: Delaware Suite644 3:00 PMChim3 as a New Transgene for Anti-HIV-1/AIDS Gene Therapy:Antiviral Effect and Survival Advantage Features in a Preclinical InVitro ModelSimona Porcellini, Luca Alberici, Francesco Gubinelli, Gian-Paolo Rizzardi, ChiaraBovolenta.645 3:15 PMIn Vivo Selection of CD4 + T Cells Transduced with a Gamma-Retroviral Vector Expressing a Single-Chain Intrabody DirectedAgainst HIV-1 TatStephen E. Braun, Ran Taube, Quan Zhu, Fay E. Wong, Akikazu Murakami, Erick Kamau,Markryan Dwyer, Angela Carville, R. Paul Johnson, Wayne A. Marasco.646 3:30 PMSafety and Efficacy of Autologous CD4+ T cells Transduced with aLentiviral Vector Delivering Anti-HIV RNA Antisense env in HIV+Subjects Failing One or More HAART RegimensTessio Rebello, David Stein, Gary Blick, Richard Greenberg, Clifford Kinder, AndrewZolopa, Gerard McGarrity.647 3:45 PMLentiviral Delivery of TRIM-Cyclophilin Restriction Factors AgainstHIV-1Emma Chan, Torsten Schaller, Lu Zhao, Adrian Thrasher, Greg Towers, Waseem Qasim.648 4:00 PMDNA Vaccination with a Consensus H1HA Influenza ImmunogenInduces Immune Responses Capable of Protecting from a Lethal NovelA/H1N1-2009 and A/H1N1-1918 ChallengeM. P. Morrow, J. Yan, A. Khan, M. Pope, A. Patel, G. Kobinger, D. B. Weiner, N. Y.Sardesai.649 4:15 PMInduction of Immune Responses Against Multiple Species ofEbolavirus Using DNA and Retroviral-Based Virus-Like ParticlesBearing the Envelope Glycoprotein of a Single Species ZaireEbolavirusWu Ou, Josie Delisle, Carolyn Wilson.650 4:30 PMLow Levels of CXCR4 Are Sufficient for HIV-1 Entry and InfectionJinyun Yuan, Charles DeRossi, Michael C. Holmes, Philip D. Gregory, Bruce E. Torbett.651 4:45 PMOverexpression of the SLAM Receptor Adaptor Molecule EAT-2 as aNovel Strategy for Enhancing Cellular Immunity to HIVantigensYasser A. Aldhamen, Daniel M. Appledorn, Sergey S. Seregin, Joyce C. Liu, Nathan J.Schuldt, Sarah S. Godbehere, Andrea Amalfitano.Oral Abstract Session 432Cancer – Immunotherapy II3:00 PM - 5:00 PMRoom: Marriott Ballroom Salons 2 & 3652 3:00 PMA Powerful Retroviral Vector for TCR Gene Therapy: Silencing ofEndogenous TCR Improved Expression and Anti-Tumor Reactivity ofTransduced Tumor-Specific TCRs in Human LymphocytesSachiko Okamoto, Hiroaki Ikeda, Hiroshi Fujiwara, Masaki Yasukawa, Hiroshi Shiku,Junichi Mineno.653 3:15 PMOrgan Specific Oncolytic Virus Incorporated Antigen Libraries(OSOVIAL) for the Immunotherapy of CancerJose Pulido, Timothy Kottke, Jill Thompson, Peter Selby, Alan Melcher, Richard Vile.654 3:30 PMEditing Human Lymphocyte Specificity for Safe and Effective AdoptiveImmunotherapy of LeukemiaElena Provasi, Pietro Genovese, Zulma Magnani, Angelo Lombardo, Andreas Reik, LiuPei-Qi, Oscar Muniz Pello, Jurgen Kuball, Attilio Bondanza, Giulia Casorati, Philip D.Gregory, Claudio Bordignon, Michael C. Holmes, Philip D. Greenberg, Luigi Naldini,Chiara Bonini.655 3:45 PMConstitutive 4-1BBL Expression Dramatically Increases Proliferation,Survival and In Vivo Persistence of CD19-Targeted T Cells, PromotingComplete Tumor EliminationMaud Condomines, Jason Plotkin, John C. Markley, Gertrude Gunset, Michel Sadelain.EXHIBITOR PROSPECTUSfinal program