FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 99<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
873<br />
Adenovirus Polypeptide IIIa as a Novel Locale for<br />
Incorporation <strong>of</strong> Heterologous Peptides<br />
Joel N. Glasgow, Elena Kashentseva, Igor P. Dmitriev, David T.<br />
Curiel<br />
874<br />
Long-Term Transgene Expression In Vivo from a Helper<br />
Dependent Adenovirus—Epstein-Barr Virus Hybrid<br />
Vector<br />
Sean D. Gallaher, Jose S. Gil, Oliver Dorigo, Arnold J. Berk<br />
875<br />
Adenoviral Vector Targeting – New Targets for Old<br />
Capsids<br />
Douglas E. Brough, Hinrich Staecker, Masaki Akiyama, Chi<br />
Hsu, Selva R. Murugesan, David A. Einfeld, Jason G. Gall,<br />
Lisa L. Wei, Melissa Hamilton, Duncan McVey C. Richter<br />
King<br />
876<br />
Development <strong>of</strong> a Novel Adenovirus-Alphavirus Hybrid<br />
Vector Providing High Efficacy and Safety in the Treatment<br />
<strong>of</strong> Liver Cancer<br />
Min Guan, Cristian Smerdou, Juan R. Rodriguez-Madoz, M.<br />
Gabriela Kramer, Stefan Kochanek, Jesus Prieto, Cheng Qian<br />
877<br />
Long-Term Transgene Expression with a Second <strong>Gene</strong>ration<br />
Hybrid AdenoRetroviral Vector<br />
Changyu Zheng, Weitan Zhang, Joseph M. Vitolo, Bruce J.<br />
Baum<br />
878<br />
Toward ‘Pseudotyping’ Adenovirus Vectors: Efficient<br />
<strong>Gene</strong>ration <strong>of</strong> pIX-Expressing Helper <strong>Cell</strong> Lines<br />
Rob C. Hoeben, Taco G. Uil, Jeroen De Vrij, Leif Lindholm,<br />
Jort Vellinga<br />
879<br />
Transduction Enhancement by the Adenovirus/Polymer<br />
Complexes Derivatized with Protein Transduction<br />
Domain Peptides<br />
Ilia Fishbein, Ivan S. Alferiev, Richard Gaster, Michael Chorny,<br />
Origene Nyanguile, Robert J. Levy<br />
880<br />
AAV-Rep 78 Mediated Rescue <strong>of</strong> a 27kb Transgene<br />
Cassette from a Helper-Dependent Ad Vector Genome<br />
Hongjie Wang, Dmitry Shayakhmetov, Andre Lieber<br />
881<br />
Development <strong>of</strong> Novel E1-Complementary <strong>Cell</strong>s for<br />
Adenoviral Production Free <strong>of</strong> Replication Competent<br />
Adenovirus<br />
Deborah Farson, Lucy Tao, Derek Ko, Thomas Harding,<br />
Dominic Brignetti, De-Chao Yu, Yuanhao Li<br />
882<br />
Development <strong>of</strong> a Transposon-Based Approach to<br />
Identification <strong>of</strong> Novel Transgene Insertion Sites within<br />
Replicating Viral Genomes<br />
Peter Kretschmer, Fang Jin, Cecile Chartier, Paul Harden, Terry<br />
Hermiston<br />
883<br />
Gold Nanoparticles as an Amplifying Payload Strategy for<br />
Adenoviral Cancer <strong>Gene</strong> <strong>Therapy</strong><br />
Maaike Everts, Jennifer L. Leddon, Robbert J. Kok, Meredith A.<br />
Preuss, C. Leigh Millican, David E. Nikles, Duane T. Johnson,<br />
David T. Curiel<br />
884<br />
Integration <strong>of</strong> a Helper-Dependent Adenovirus Mediated<br />
by the Phage FðC31 Integrase<br />
Rénald Gilbert, Laurie Desfossé, Émilie Mairey, Benoît<br />
Raymond, Michele P. Calos, Jacques P. Tremblay, Bernard<br />
Massie<br />
885<br />
Calcium Phosphate Coprecipitation Enhances Adenoviral<br />
Vector-Based <strong>Gene</strong> Transfer to Murine Bone Marrow<br />
Derived Dendritic <strong>Cell</strong>s<br />
Michael P. Seiler, Vincenzo Cerullo, Philip Ng, Donna Palmer,<br />
Brendan Lee<br />
886<br />
An Adenovirus Vector with a Chimeric Fiber Derived<br />
from Ovine Adenovirus for Novel Tropism Discovery<br />
Masaharu Nakayama, Joel N. Glasgow, Gerald W. Both,<br />
Massimo Palmarini, Yuko Tsuruta, Kenzaburo Tani, Joanne T.<br />
Douglas, David T. Curiel<br />
887<br />
Reducing the Incidence <strong>of</strong> Replication Competent<br />
Adenovector by Engineering the Vector Genome<br />
G. Campbell Kaynor, Jennifer L. Brown, Rhonda Brown,<br />
Xinzhong Wang<br />
888<br />
Optimization <strong>of</strong> Adenovirus Serotype 35 Vectors for<br />
Efficient Transduction in Human Hematopoietic Progenitors;<br />
Comparison <strong>of</strong> Promoter Activities<br />
Fuminori Sakurai, Hiroyuki Mizuguchi, Kenji Kawabata,<br />
Teruhide Yamaguchi, Takao Hayakawa<br />
889<br />
Lanthanum Enhances Adenovirus-Mediated <strong>Gene</strong><br />
Transfer<br />
Oliver B. Betz, Glyn D. Palmer, Volker M. Betz, Keith<br />
Crawford, Christopher Niyibizi, Mark S. Vrahas, Christopher<br />
H. Evans