FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 77<br />
ABSTRACTS<br />
FRIDAY, JUNE 3<br />
514<br />
Effect <strong>of</strong> DNA-PKcs on AAV Replication<br />
Young-Kook Choi, Irene Zolotukhin, Barry J. Byrne, Sihong<br />
Song<br />
515<br />
Overlapping Adeno-Associated Viral (AAV) Vector<br />
Mediated <strong>Gene</strong> Transfer Is Dependent on Viral Serotype<br />
and the Transgene Sequence in Skeletal Muscle<br />
Arkasubhra Ghosh, Yongping Yue, Dongsheng Duan<br />
516<br />
Analysis <strong>of</strong> AAV Serotype 8 Vector Integration in Normal<br />
and DNA-PKcs-Deficient Scid Mice by a Novel Strategy<br />
Katsuya Inagaki, Xiaolin Wu, Sally Fuess, Theresa A. Storm,<br />
Mark A. Kay, Hiroyuki Nakai<br />
517<br />
Type 1 Rep52 Is Superior to Authentic Rep52 for Producing<br />
Recombinant Adeno-Associated Virus Type 5 in<br />
Insect <strong>Cell</strong>s<br />
Masashi Urabe, Takayo Nakakura, Hiroaki Mizukami,<br />
Akihiro Kume, Robert M. Kotin, Keiya Ozawa<br />
518<br />
Production <strong>of</strong> Recombinant Type 2 Adeno-Associated<br />
Virus in Bioreactors<br />
Yves Durocher, Phuong Lan Pham, Gilles St-Laurent, Danielle<br />
Jacob, Brian Cass, Josephine Nalbantoglu, Amine Kamen<br />
519<br />
Selective Inactivation <strong>of</strong> Helper Adenovirus with High<br />
Hydrostatic Pressure for AAV-2 Vector Production<br />
Joshua N. Leonard, David V. Schaffer, Peter Ferstl, Antonio<br />
Delgado<br />
520<br />
The Effects <strong>of</strong> Transgene and Cassette Size on Recombinant<br />
AAV2 Production and Expression<br />
Corinne M. Goldsmith, Antonis Voutetakis, Bruce J. Baum<br />
521<br />
Spliceosome-Mediated RNA Trans-Splicing with rAAV<br />
Partially Restores CFTR Function to Polarized Human<br />
CF Airway Epithelial <strong>Cell</strong>s<br />
Xiaoming Liu, Meihui Luo, Liang N. Zhang, Ziying Yan, Wei<br />
Ding, Roman Zak, Gary S. Mansfield, Lloyd G. Mitchell, John<br />
F. Engelhardt<br />
522<br />
Enhanced Repair <strong>of</strong> Articular Cartilage Defects in Rabbits<br />
by Overexpression <strong>of</strong> Human FGF-2 Via rAAV-Mediated<br />
<strong>Gene</strong> Transfer<br />
Magali Cucchiarini, Henning Madry, Chunyan Ma, Tanja<br />
Thurn, David Zurakowski, Dieter Kohn, Michael D. Menger,<br />
Stephen B. Trippel, Ernest F. Terwilliger<br />
523<br />
AAV Transcytosis through Barrier Epithelia and Endothelium<br />
Giovanni Di Pasquale, John A. Chiorini<br />
Adenovirus Vectors: Applications<br />
524<br />
Adenovirus-Mediated <strong>Gene</strong> Delivery <strong>of</strong> Decoy Death<br />
Receptors Protects Mice from Hepatitis<br />
Delphyne Descamps, Frédéric Vigant, Stéphanie Esselin,<br />
Elisabeth Connault, Paule Opolon, Michel Perricaudet, Karim<br />
Benihoud<br />
525<br />
Optimized <strong>Gene</strong> Transfer into Mesenchymal Stem <strong>Cell</strong>s<br />
and Embryonic Stem <strong>Cell</strong>s by Modified Adenovirus<br />
Vectors<br />
Hiroyuki Mizuguchi, Kenji Kawabata, Fuminori Sakurai,<br />
Tomomi Sasaki, Teruhide Yamaguchi, Takao Hayakawa<br />
526<br />
Conditionally Replicative Adenoviruses Designed to<br />
Restore Defects in the p53 Pathway for Effective<br />
Virotherapy <strong>of</strong> Cancer<br />
Victor W. van Beusechem, Danielle A. M. Heideman, Jan E.<br />
Carette, Martin Scheffner, Ramon Alemany, Winald R.<br />
Gerritsen<br />
527<br />
Reductions in Tissue Transduction and Toxicity after<br />
Systemic Administration <strong>of</strong> Adenovirus Vectors Containing<br />
Fiber-Shaft Exchange in Combination with both<br />
CAR- and av Integrin-Binding Ablation<br />
Naoya Koizumi, Hiroyuki Mizuguchi, Kenji Kawabata,<br />
Fuminori Sakurai, Yoshiteru Watanabe, Takao Hayakawa<br />
528<br />
Infectivity Enhancement <strong>of</strong> a <strong>Gene</strong>tic Fiber Mosaic<br />
Adenovirus Vector in Ovarian Cancer <strong>Cell</strong>s<br />
Yuko Tsuruta, Larisa Pereboeva, Joel N. Glasgow, Yosuke<br />
Kawakami, David T. Curiel<br />
529<br />
Oncolytic Virotherapy Employing flt-1 Driven mda-7/IL-<br />
24 <strong>Gene</strong> Delivery<br />
Sergey A. Kaliberov, Lyudmila N. Kaliberova, Amy S. Petersen,<br />
Valentina Krendelchtchikova, Victor Krasnykh, Donald J.<br />
Buchsbaum<br />
530<br />
Adenoviral and Hydrodynamic <strong>Gene</strong> Transfer <strong>of</strong> Replicating<br />
Episomes Result in Stable Transgene Expression<br />
after Partial Hepatectomy in Mice<br />
Jan Snoeys, Désiré Collen, Bart De Geest
Change language