FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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62<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
THURSDAY, JUNE 2<br />
Cancer - Immunotherapy: <strong>Gene</strong>tically Modified<br />
Antigen Presenting <strong>Cell</strong>s and Adjuncts<br />
267<br />
Inflammatory Killing <strong>of</strong> Normal <strong>Cell</strong>s To Treat Metastatic<br />
Tumors<br />
Luis Sanchez-Perez, Gregory Daniels, Timothy Kottke, Rosa<br />
Maria Diaz, Atique Ahmed, Jill Thompson, Heung Chong,<br />
Richard Vile<br />
268<br />
Primary Mouse Marrow Stromal <strong>Cell</strong>s Behave as Antigen-Presenting<br />
<strong>Cell</strong>s in Syngeneic Immune Responses<br />
John Stagg, Sandra Pommey, Jacques Galipeau<br />
269<br />
Stimulation <strong>of</strong> the Immune System Using <strong>Gene</strong> <strong>Therapy</strong><br />
Is an Effective Approach for Treating Brain Tumors in<br />
Mouse and Rat Models<br />
James F. Curtin, Gwendalyn D. King, Weidong Xiong,<br />
Chunyan Liu, Pedro R. Lowenstein, Maria G. Castro<br />
270<br />
Vaccination <strong>of</strong> Recurrent Glioma Patients with Tumor<br />
Lysate-Pulsed Dendritic <strong>Cell</strong>s Elicits Immune Responses:<br />
Results <strong>of</strong> a Clinical Phase I/II Trial<br />
Ryuya Yamanaka, Junpei Homma, Masuhiro Takahashi,<br />
Ryuichi Tanaka<br />
271<br />
Interactions between Replicating Virotherapy and Tumor<br />
Growth in the Presence <strong>of</strong> an Intact Immune System<br />
Michael Forshaw, Caroline Cole, Timothy Kottke, Jill Thompson,<br />
Jian Qiao, Peter Selby, Alan Melcher, Richard Vile<br />
272<br />
Induction <strong>of</strong> Anti-Tumoral Immune Response and IFN-<br />
Regulated Factors by Delivery <strong>of</strong> Control DNA<br />
Shulin Li, Miles Wilkinson, Xueqing Xia, Michael David,<br />
Lihong Xu<br />
273<br />
Effects <strong>of</strong> Pre-Existing Immunity on <strong>Gene</strong> <strong>Therapy</strong><br />
Mediated by First <strong>Gene</strong>ration or High Capacity Adenoviral<br />
Vectors Expressing Flt3L in a Syngeneic Glioma<br />
Model<br />
Gwendalyn D. King, James F. Curtin, Weidong Xiong,<br />
Chunyan Liu, Donna Palmer, Philip Ng, Pedro R. Lowenstein,<br />
Maria G. Castro<br />
274<br />
<strong>Gene</strong>tic Immunotherapy Targeted to Antigen Presenting<br />
<strong>Cell</strong>s Using a CD40-Targeted Adenoviral Vector<br />
Disha A. Mody, Larry Smart, Yoshinobu Odaka, Xiao L. Li,<br />
Cigdem E. Yilmaz, Alexander V. Pereboev, J. Michael Mathis<br />
275<br />
RTVP-1 Protein Stimulates Markers <strong>of</strong> Maturation in<br />
Mouse and Human Dendritic <strong>Cell</strong>s<br />
Hongyu Wang, El Moataz Abdelfattah, Salahaldin A. Tahir,<br />
Guang Yang, Alexei Goltsov, Weihua Tian, Chengzhen Ren,<br />
Chenghui Ren, Terry L. Timme, Timothy C. Thompson<br />
276<br />
Enhancement <strong>of</strong> Cytotoxic T-Lymphocyte Responses<br />
Against Carcinoembryonic antigen (CEA) Using <strong>Gene</strong>tically<br />
Modified Dendritic <strong>Cell</strong>s Expressing CEA and<br />
CD40 Ligand<br />
Nachimuthu Chinnasamy, James Neuenfeldt, James Shaffer,<br />
Dhanalakshmi Chinnasamy<br />
277<br />
Large-Scale <strong>Gene</strong>ration <strong>of</strong> <strong>Gene</strong>tically Modified Human<br />
CD34+ Progenitor <strong>Cell</strong>-Derived Langerhans <strong>Cell</strong>s<br />
Using a Closed Culture System Suitable for Clinical<br />
Immunotherapy<br />
Jianda Yuan, Ryan Kendle, Joanna Hodges, Michel Sadelain,<br />
James W. Young, Isabelle Riviere<br />
278<br />
Induction <strong>of</strong> Anti-Tumor Activity with Dendritic <strong>Cell</strong>s<br />
Loaded with Tumor <strong>Cell</strong> Lysates or Adenoviral Vector-<br />
Encoding Tumor-Associated Antigens<br />
Jae-Gyun Jeong, Hwang-Jae Lee, Hae-Sook Ahn, Sung-Min<br />
Oh, Seong-Hyun Ho, Hongchan Cho, Seok Kang, Jong-Mook<br />
Kim, Sunyoung Kim, Sujeong Kim<br />
279<br />
A Novel Functionalized Polymeric Formulation for use<br />
in Delivering Therapeutic <strong>Gene</strong>s for the Treatment <strong>of</strong><br />
Solid Tumors<br />
Jason Fewell, Majed Matar, Jennifer Rice, Gregory Slobodkin,<br />
Bruce Hovanes, Khursheed Anwer<br />
280<br />
Effect <strong>of</strong> Polysaccharides from Medicinal Herbs as<br />
Danger Signals: Implication for Regulating Immune<br />
Responses<br />
Chih-Chien Shu, Jeng-Hwan Wang, Su-Jane Wang, Jih-Chun<br />
Wen, Wen-Chi Wei, Yi-Fu Yen, Kin-Yuen Cheng, Lie-Fen<br />
Shyur, Ning-Sun Yang<br />
281<br />
Evaluation <strong>of</strong> Plant Polysaccharides and Phyto-Compounds<br />
on Inflammation-Associated Tumorigenesis by<br />
Using Melanoma DNA Vaccine Model<br />
Su-Jane Wang, Jeng-Hwan Wang, Wen-Chi Wei, Chih-Chien<br />
Shu, Lie-Fen Shyur, Ning-Sun Yang<br />
282<br />
Effects <strong>of</strong> Fas Ligand on Inflammation and Tumor<br />
Survival Are Dependent on Its Expression Levels<br />
Masatoshi Tagawa, Akihiko Wada, Jiyang O-Wang, Kiyoko<br />
Kawamura, Osamu Shimozato, Yuji Tada, Yuichi Takiguchi,<br />
Koichiro Tatsumi, Takayuki Kuriyama
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