<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 45 MAP OF ST. LOUIS
46 8th Annual Meeting • June 1 - 5, 2005 • St. Louis ABSTRACTS THURSDAY, JUNE 2 Oral Abstract Session 240 RNA Virus Vectors: <strong>Gene</strong> Transfer and <strong>Gene</strong> Expression Room: 260/264 1 2:00 PM Persistent <strong>Gene</strong> Expression in Mouse Nasal Epithelia Following Baculovirus GP64 Pseudotyped FIV-Based <strong>Gene</strong> Transfer Patrick L. Sinn, Erin R. Burnight, Melissa A. Hickey, Gary W. Blissard, Paul B. McCray, Jr. 2 2:15 PM <strong>Cell</strong>ular Mechanisms Involved with Lentiviral <strong>Gene</strong> Transfer Shangming Zhang, Karen Pollok, Lakshmi Sastry, Lionel Berthoux, Jeremy Luban, Kenneth Cornetta 3 2:30 PM Effects <strong>of</strong> the cHS4 Insulator Elements on Transgene Expression and Biological Titer <strong>of</strong> Lentiviral Vector Hideki Hanawa, Takashi Shimada 4 2:45 PM Optimization <strong>of</strong> Globin Lentiviral Vector Design for the Treatment <strong>of</strong> bð-Thalassemia Leszek Lisowski, Stefano Rivella, Michel Sadelain 5 3:00 PM Differential Expression <strong>of</strong> PIT1 and PIT2 after G-CSF Mobilization Is Associated with Efficient <strong>Gene</strong> Transfer Using GALV-Pseudotyped Gammaretroviral Vectors Brian C. Beard, Pau Mezquita, Julia C. Morris, Hans-Peter Kiem 6 3:15 PM In Vivo Adult Stem <strong>Cell</strong> <strong>Gene</strong> Transfer in Mice by In Situ Delivery <strong>of</strong> a Self-Inactivating Lentiviral Vector Using Intrafemoral Injection D. Nicole Worsham, Kimberly Bohn, David Kuhel, David A. Williams, Christ<strong>of</strong> von Kalle, Dao Pan 7 3:30 PM Transduction <strong>of</strong> Quiescent Human <strong>Cell</strong>s Using an SIVsmmPBj-Derived Lentiviral Vector Matthias Schweizer, Nina Wolfrum, Michael Muehlebach, Julia Kaiser, Silke Schuele, Klaus Cichutek 8 3:45 PM Potent Inhibition <strong>of</strong> HIV-1 Replication by Lentiviral Vectors Carrying Anti-Vif siRNA S. Li, G. Wang, K. Meinking, M. J. Li, J. Ji, J. A. Zaia, J. J. Rossi 9 4:00 PM Coronaviruses: Development <strong>of</strong> Novel Oncolytic Vectors Tom Würdinger, Hélène M. Verheije, Victor W. van Beusechem, Xander A. M. de Haan, Winald R. Gerritsen, Peter J. M. Rottier 10 4:15 PM The Effect <strong>of</strong> Globin Locus Control Region (LCR) Elements or the MSCV-LTR on Promoter Trapping by Integrated Lentiviral Vector Genomes Byoung Y. Ryu, Derek A. Persons, Arthur W. Nienhuis Oral Abstract Session 241 AAV Vectors: Vector Biology Room: 240 Complex 11 2:00 PM An Additional Role <strong>of</strong> <strong>Cell</strong>ular FKBP52 in Recombinant Adeno-Associated Virus 2 Vector-Mediated <strong>Gene</strong> Transfer and Transgene Expression Weihong Zhao, Li Zhong, Jianqing Wu, Liyuan Chen, Keyun Qing, Kirsten A. Weigek-Kelley, Steven H. Larsen, Arun Srivastava 12 2:15 PM Self-Complementary AAV2 Vectors Transduce Liver with the Same Efficiency as AAV8: The Critical Role <strong>of</strong> Second-Strand Synthesis in AAV Biology Zhijian Wu, Hongzhe Duan, R. Jude Samulski 13 2:30 PM Persistence <strong>of</strong> AAV Capsid in Transduced <strong>Cell</strong>s Mo-Ying Hsieh, Fayaz R. Khazi, Alexander Schlachterman, Yi- Lin Liu, Katherine A. High 14 2:45 PM rAAV2 Integration Junctions Isolated without In Vivo Selection Bias Show a Preference to 5’ Regions <strong>of</strong> Open Reading Frames Fayaz R. Khazi, Alexander Schlachterman, Katherine A. High 15 3:00 PM Large-Scale Analysis <strong>of</strong> Adeno-Associated Virus Vector Integration Sites in Normal Human <strong>Cell</strong>s Daniel G. Miller, Grant D. Trobridge, Lisa M. Petek, Michael A. Jacobs, Rajinder Kaul, David W. Russell 16 3:15 PM Single-Polarity Recombinant Adeno-Associated Virus 2 Vector-Mediated Transgene Expression In Vitro and In Vivo: Mechanism <strong>of</strong> Transduction Li Zhong, Xiaohuai Zhou, Yanjun Li, Keyun Qing, Richard J. Samulski, Arun Srivastava 17 3:30 PM Visualization <strong>of</strong> the Intranuclear rAAV Replication Centers and Their Co-Localization with Double- Stranded DNA Break Repair Proteins Cervelli Tiziana, Lorena Zentilin, Alessandro Marcello, Mauro Giacca
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