FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 65<br />
ABSTRACTS<br />
THURSDAY, JUNE 2<br />
319<br />
ColoAd1, a Chimeric Ad11p/Ad3 Oncolytic Virus for the<br />
Treatment <strong>of</strong> Colon Cancer<br />
Irene Kuhn, Paul Harden, Maxine Bauzon, Terry Hermiston<br />
320<br />
Antitumor Effect <strong>of</strong> Intrahepatic Interleukin-12 Expression<br />
from a Regulable Plasmid Vector in Murine Models<br />
<strong>of</strong> Primary and Metastatic Liver Cancer<br />
Maider Zabala, Ruben Hernandez-Alcoceba, Margarita Ecay,<br />
Ignacio Melero, Christine Perret, Ivan Penuelas, Jesus Prieto,<br />
Gabriela M. Kramer<br />
321<br />
Splice-Switching <strong>of</strong> the Prostate Specific Membrane<br />
Antigen (PSMA) in LnCap Prostate Cancer <strong>Cell</strong>s<br />
Tiffany L. Williams, Ryszard Kole<br />
322<br />
Tumor Specific Activation <strong>of</strong> Irinotecan by a<br />
Carboxylesterase Fused with Anti CEA scFv<br />
Junji Uchino, Koichi Takayama, Tomomichi Sone, Akiko<br />
Harada, Taishi Harada, David T. Curiel, Yoichi Nakanishi<br />
323<br />
Transcriptional Targeting <strong>of</strong> Viral <strong>Gene</strong> Transfer by<br />
Human Hexokinase II Promoter<br />
Ann-Marie Maatta, Sanna Korja, Tanja Hakkarainen, Jarmo<br />
Wahlfors, Kimmo Mäkinen, Esko Alhava, Riikka Pellinen<br />
324<br />
TRAIL <strong>Gene</strong> <strong>Therapy</strong> Is a Promising <strong>Therapy</strong> for<br />
Bladder Cancer<br />
Ahmed M. El-Zawahry, Christina Voelkel-Johnson<br />
325<br />
Identification <strong>of</strong> <strong>Gene</strong>s Expressed Specifically in Esophageal<br />
Cancer <strong>Cell</strong>s<br />
Fumiaki Sati, John M. Abraham, Jing Yin, Takatsugu Kan,<br />
Yuriko Mori, Stephen J. Meltzer<br />
326<br />
<strong>Gene</strong> Therapeutic Overexpression <strong>of</strong> MDR1 Affects<br />
Transcriptional Regulations <strong>of</strong> Proteins Involved in<br />
Apoptosis and Detoxification<br />
Patrick Maier, Li Li, Katharina Fleckenstein, Stephanie Laufs,<br />
Stefan Fruehauf, Jens Zeller, Frederik Wenz, Carsten Herskind<br />
327<br />
The Effect <strong>of</strong> NO on HIF-Mediated <strong>Gene</strong> Expression:<br />
Chemical Sources <strong>of</strong> NO Versus <strong>Gene</strong>tic Regulation <strong>of</strong><br />
iNOS<br />
Rana S. Al-Assah, Rachel L. Cowen, Edwin C. Chinje, Ian J.<br />
Stratford<br />
(Note: Abstract 328 has been moved from Poster<br />
Session I to Poster Session III and will follow Abstract<br />
1029.)<br />
328<br />
An Orthotopic Murine Model <strong>of</strong> Advanced Breast<br />
Cancer for Imaging and Comparison <strong>of</strong> Targeting<br />
Moieties<br />
Tuuli Ranki, Anna Kanerva, Karl von Smitten, Merja Sarkioja,<br />
Lotta Kangasniemi, Mari Raki, Pirjo Laakkonen, Hongju Wu,<br />
David T. Curiel, Steven Goodison Akseli Hemminki<br />
329<br />
Use <strong>of</strong> Recombinant Non-Pathogenic Bacteria as Vectors<br />
for Hypoxia Targeted <strong>Gene</strong> Expression for Cancer <strong>Gene</strong><br />
<strong>Therapy</strong><br />
Asferd Mengesha, Ludwig Dobois, Brad G. Wouters, Phillipe<br />
Lambin, Jan Theys<br />
Hematologic - Disease Models<br />
330<br />
Lentiviral Vector Mediated Hematopoietic Stem <strong>Cell</strong><br />
<strong>Gene</strong> <strong>Therapy</strong> Combined with Non-Lethal Conditioning<br />
Restores T <strong>Cell</strong> Function in the Murine Model <strong>of</strong><br />
Wiskott-Aldrich Syndrome<br />
Francesco Marangoni, Loïc Dupré, Samantha Scaramuzza,<br />
Sara Trifari, Raisa J<strong>of</strong>ra Hernández, Adrian Thrasher, Anne<br />
Galy, Alessandro Aiuti, Luigi Naldini, Maria Grazia Roncarolo<br />
331<br />
Lentivirus-Mediated Ex Vivo <strong>Gene</strong> <strong>Therapy</strong> in ADA-<br />
Deficient SCID Mice<br />
Alessandra Mortellaro, Raisa J<strong>of</strong>ra Hernández, Matteo Guerrini,<br />
Antonella Tabucchi, Filippo Carlucci, Antonia Follenzi, Luigi<br />
Naldini, Claudio Bordignon, Maria Grazia Roncarolo,<br />
Alessandro Aiuti<br />
332<br />
Chronic Granulomatous Disease <strong>Gene</strong> <strong>Therapy</strong> Functionally<br />
Corrects the Phenotype <strong>of</strong> Polymorphonuclear<br />
Leukocytes (PMN)<br />
Ulrich Siler, Marion G. Ott, Stefan Stein, Elke Karaus, Maja<br />
Rutishauser, Corinne Wenk, Dieter Hoelzer, Manuel Grez,<br />
Reinhard Seger<br />
333<br />
Preferential Targeting <strong>of</strong> Transcriptional Start Sites after<br />
Retroviral-Mediated T-<strong>Cell</strong> <strong>Gene</strong> <strong>Therapy</strong> for Adenosine<br />
Deaminase Deficiency<br />
Daniele Moratto, Jayashree G. Jagadeesh, Akihiro Konno,<br />
Marita Bosticardo, Gregory E. Crawford, Ingeborg Holt, Linda<br />
M. Muul, Shepherd H. Shurman, Tyra Wolfsberg, Fabio<br />
Candotti<br />
334<br />
Treatment <strong>of</strong> Anemia in Mice with Chronic Renal Failure<br />
Utilizing Erythropoietin-Secreting <strong>Gene</strong>tically-Engineered<br />
Murine Bone Marrow Stromal <strong>Cell</strong>s<br />
Nicoletta Eliopoulos, Raymonde F. Gagnon, Moira Francois,<br />
Jacques Galipeau
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