FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 107<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
Cancer - Targeted <strong>Gene</strong> <strong>Therapy</strong>: Targeting <strong>of</strong> Adenoviral<br />
Vectors<br />
1004<br />
Enhanced Survival Uncovers Liver Toxicity in Mice with<br />
Orthotopic Advanced Ovarian Cancer Treated with<br />
Gemcitabine and Ad5/3-Dð24, a Serotype 3 Receptor<br />
Targeted Oncolytic Adenovirus<br />
Mari Raki, Anna Kanerva, Ari Ristimaki, Renee A. Desmond,<br />
Dung T. Chen, Tuuli Ranki, Merja Sarkioja, Lotta<br />
Kangasniemi, Akseli Hemminki<br />
1005<br />
Replication and Anti-Tumor Efficacy <strong>of</strong> Conditionally<br />
Replicating Adenoviral Vectors for Glioma Treatment<br />
Maarten ter Horst, Mark Rodijk, Eric Brouwer, Rob C.<br />
Hoeben, Bertie de Leeuw, Peter A. E. Sillvis Smitt<br />
1006<br />
Analysis <strong>of</strong> Resistance to Viral Oncolysis in Primary<br />
Ovarian Cancer <strong>Cell</strong> Cultures<br />
Robert Strauss, Pavel Sova, Shaoheng Ni, Nancy Kiviat, Nicole<br />
Urban, Andre Lieber<br />
1007<br />
<strong>Gene</strong>tic Strategies to Improve Oncolytic Adenoviruses<br />
for Targeted and Efficient Virotherapy <strong>of</strong> Malignant<br />
Melanoma<br />
Stephan Schierer, Daniela Kosmides, Angel A. Rivera, Andrea<br />
Hesse, Astrid Mainka, Andrea L. Volk, Gerold Schuler, David<br />
T. Curiel, Dirk M. Nettelbeck<br />
1008<br />
Prostate-Specific Oncolytic Adenovirus Based on<br />
Bidirectional TSTA System<br />
Makoto Sato, Mai Johnson, Sanjiv S. Gambhir, Michael Carey,<br />
Lily Wu<br />
1009<br />
<strong>Gene</strong> <strong>Therapy</strong> for Prostate Cancer by Controlling<br />
Adenovirus E1A and E4 <strong>Gene</strong> Expression with PSES<br />
Enhancer<br />
Xiong Li, YanPing Zhang, Hong-sup Kim, Kyung-Hee Bae,<br />
Keith M. Stantz, Sang-Jin Lee, Chaeyong Jung, Juan A.<br />
Jiménez, Thomas A. Gardner, Meei-Huey Jeng Ching-hai Kao<br />
1010<br />
A bð-hCG Expressing Trackable and Tumor Targeted<br />
Conditionally Replicating Adenovirus for Treatment <strong>of</strong><br />
Prostate Cancer<br />
Maria Rajecki, Anna Kanerva, Lotta Kangasniemi, Kah-Whye<br />
Peng, Merja Sarkioja, Ulf-Hakan Stenman, Henrik Alfthan,<br />
Akseli Hemminki<br />
1011<br />
A Combination <strong>of</strong> Ceramide Analogue and FasL <strong>Gene</strong><br />
<strong>Therapy</strong> Can Be a Potential Novel <strong>Therapy</strong> for Prostate<br />
Cancer<br />
Ahmed El-Zawahry, David Holman, Xiang Liu, Saeed<br />
Elojaem, Alicja Bielawaska, Jacek Bielwaski, Zdislaw Szulc,<br />
Yusuf Hannun, James S. Norris<br />
1012<br />
Survivin-Responsive Conditionally Replicating Adenovirus<br />
Exhibits Strictly Cancer-Specific and Efficient Viral<br />
Replication<br />
Ken-ichiro Kosai, Junichi Kamizono, Satoshi Nagano, Yoshiteru<br />
Mur<strong>of</strong>ushi, Setsuro Komiya<br />
1013<br />
Pharmacology <strong>of</strong> Tropism Modified Adenovectors for<br />
<strong>Therapy</strong> <strong>of</strong> Disseminated Cancer<br />
Masaki Akiyama, Selva Murugesan, David A. Einfeld, Douglas<br />
E. Brough, Jason G. Gall, Thomas J. Wickham, C. Richter<br />
King<br />
1014<br />
Adenovirus-Mediated MUC1-Driven Expression <strong>of</strong> the<br />
Sodium Iodide Symporter (NIS) in Pancreatic Tumors<br />
Provides for In Vivo Radioiodide Imaging and <strong>Therapy</strong><br />
Roisin M. Dwyer, Elizabeth R. Bergert, Michael K. O’Connor,<br />
Sandra J. Gendler, John C. Morris<br />
1015<br />
Inhibition <strong>of</strong> Tumor Growth in Xenografted Nude Mice<br />
with Adenovirus-Mediated Endostatin <strong>Gene</strong> Comparison<br />
with Recombinant Endostatin Protein<br />
Zhihui Liang, Wenlin Huang<br />
1016<br />
Retargeted Selectively Replicating Adenoviruses in<br />
Combination with Antiangiogenic <strong>Therapy</strong> for the<br />
<strong>Therapy</strong> <strong>of</strong> Colon Cancer<br />
Krisztian Homicsko, Alexander Lukashev, Richard Iggo<br />
1017<br />
Selective Induction <strong>of</strong> Tumor-Associated Antigens in<br />
Murine Pulmonary Vasculature Using Double-Targeted<br />
Adenoviral Vectors<br />
Maaike Everts, SangAe Kim-Park, Meredith A. Preuss, Michael<br />
J. Passineau, Joel N. Glasgow, Alexander V. Pereboev,<br />
Parameshwar J. Mahasreshti, William E. Grizzle, Paul N.<br />
Reynolds, David T. Curiel<br />
1018<br />
Infectivity Enhancement for Ovarian Cancer and Glioma<br />
Via a Novel Human Adenoviral Vector with a Chimeric<br />
Fiber Derived from Canine Adenovirus Type 1<br />
Mariam A. St<strong>of</strong>f-Khalili, Angel A. Rivera, Joel N. Glasgow,<br />
Long P. Le, Alexander St<strong>of</strong>f, Maaike Everts, Yuko Tsuruta,<br />
Yusoke Kawakami, J. Michael Mathis, Larisa Pereboeva Peter<br />
Dall, David T. Curiel
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