FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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94<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
794 12:00 PM<br />
Evaluation <strong>of</strong> <strong>Gene</strong> Transfer Efficacy Mediated by AAV1<br />
and AAV6 Vectors in Skeletal Muscle <strong>of</strong> Adult Mice<br />
Following Different Routes <strong>of</strong> Administration<br />
Christel Rivière, Karine Poulard, Gabor Veres, Olivier Danos,<br />
Anne M. Douar<br />
Oral Abstract Session 415<br />
<strong>Cell</strong>ular Immunotherapy <strong>of</strong> Cancer Using <strong>Gene</strong>tically<br />
Modified Effectors<br />
Room: Ferrara Theater<br />
795 10:15 <strong>AM</strong><br />
The Use <strong>of</strong> Autologous LMP2-Specific Cytotoxic T<br />
Lymphocytes for the Treatment <strong>of</strong> Relapsed EBV +ve<br />
Hodgkin Disease and Non-Hodgkin Lymphoma<br />
Catherine M. Bollard, Stephen Gottschalk, Elizabeth Buza,<br />
Helen Huls, Vicky Gresik, George Carrum, Malcolm K.<br />
Brenner, Cliona M. Rooney, Helen E Heslop<br />
796 10:30 <strong>AM</strong><br />
In Vivo Elimination <strong>of</strong> Human Leukaemia <strong>Cell</strong>s by WT1<br />
Specific TCR Transduced T <strong>Cell</strong>s<br />
Shao-An Xue, Liquan Gao, Daniel Hart, Waseem Qasim,<br />
Adrian Thrasher, Jane Apperley, Wolfgang Uckert, Emma<br />
Morris, Hans Stauss<br />
797 10:45 <strong>AM</strong><br />
Targeted Elimination <strong>of</strong> Prostate Cancer by <strong>Gene</strong>tically<br />
Directed Human T Lymphocytes<br />
Matthias Stephan, Terence P. F. Gade, Waleed Hassen, Elmer<br />
Santos, Gertrude Gunset<br />
798 11:00 <strong>AM</strong><br />
Epstein Barr Virus-Specific Cytotoxic T Lymphocytes<br />
(EBV-CTL) Expressing an Anti-CD30 Chimeric T-<strong>Cell</strong><br />
Receptor (cTcR) for the Treatment <strong>of</strong> Hodgkin’s Disease<br />
(HD)<br />
Barbara Savoldo, Cliona Rooney, Helen Heslop, Hinrich<br />
Abken, Andreas Hombach, Lan Zhang, Martin Pule,<br />
Gianpietro Dotti, Malcolm Brenner<br />
799 11:15 <strong>AM</strong><br />
In Vitro and In Vivo Characterization <strong>of</strong> “Second-<strong>Gene</strong>ration”<br />
Co-Stimulatory Chimeric Antigen Receptors<br />
(CARs) Targeting the CD19 Antigen Present on B <strong>Cell</strong><br />
Malignancies<br />
Renier J. Brentjens, Yan Nikhamin, Miko Matsushita, Michel<br />
Sadelain<br />
800 11:30 <strong>AM</strong><br />
Adenoviral Transduced Monocytes: Efficient Antigen<br />
Presenting <strong>Cell</strong>s for the Activation <strong>of</strong> Antigen-Specific T<br />
<strong>Cell</strong>s<br />
Ann M. Leen, Maheshika K. Ratnayake, Aaron E. Foster,<br />
Cliona M. Rooney, Stephen Gottschalk<br />
801 11:45 <strong>AM</strong><br />
Fas Knockdown Mediated by siRNA in EBV-Specific<br />
Cytotoxic T-Lymphocytes (CTL) Reduces Their Sensitivity<br />
to Fas/FasL-Induced Apoptosis<br />
Gianpietro Dotti, Barbara Savoldo, Martin Pule, Karin C.<br />
Straath<strong>of</strong>, Ettore Biagi, Eric Yvon, Sthephane Vigouroux,<br />
Cliona M. Rooney, Malcolm K. Brenner<br />
802 12:00 PM<br />
Use <strong>of</strong> Chemokine Expression at a Tumor Site to<br />
Enhance Immune <strong>Cell</strong> Trafficking for Melanoma<br />
<strong>Therapy</strong><br />
Uma Thanarajasingam, Laura Sanz, Rosa Maria Diaz, Jill<br />
Thompson, Michael Gough, Richard Vile<br />
Oral Abstract Session 416<br />
Cancer-Apoptosis and Suicide<br />
Room: 123/127<br />
803 10:15 <strong>AM</strong><br />
The Effects <strong>of</strong> Intratumoral Injection <strong>of</strong> a Replicating<br />
Morbillivirus in a Canine Model <strong>of</strong> Naturally Occurring<br />
Lymphoma<br />
Michael S. Henson, Steven E. Suter, Veronika A. von Messling,<br />
Roberto Cattaneo, Adele K. Fielding<br />
804 10:30 <strong>AM</strong><br />
HSVtk Mediated Immunostimulatory Tumor <strong>Cell</strong> Killing<br />
Enhances Adoptive T <strong>Cell</strong> <strong>Therapy</strong> in a B16 Melanoma<br />
Model<br />
Luis Sanchez-Perez, Michael Gough, Jian Qiao, Uma<br />
Thanarajasingam, Atique Ahmed, Rosa Maria Diaz, Richard<br />
Vile<br />
805 10:45 <strong>AM</strong><br />
Effective Suicide <strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong> Leukemia in a Novel<br />
Model <strong>of</strong> Retroviral Insertion<br />
Martina Blumenthal, Dianne Skelton, Denise A. Carbonaro,<br />
Karen A. Pepper, Donald B. Kohn<br />
806 11:00 <strong>AM</strong><br />
Phase I/II Trial <strong>of</strong> Intravenous NDV-HUJ (OV001)<br />
Oncolytic Virus in Recurrent Glioblastoma Multiforme<br />
Arnold I. Freeman, Zichria Zakay-Rones, John M. Gomori,<br />
Eduard Linetsky, Linda Rasooly, Amos Panet, Eugene Libson,<br />
Charles S. Irving, Tali Siegal, Eithan Galun<br />
807 11:15 <strong>AM</strong><br />
Addition <strong>of</strong> HU to GCV Induces Bystander Cytotoxicity<br />
in Co-Cultures <strong>of</strong> HSVTK-Expressing and Non-<br />
Expressing HeLa <strong>Cell</strong>s<br />
Brian G. Gentry, Paul D. Boucher, Donna S. Shewach
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