FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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92<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
762 12:00 PM<br />
Cisplatin-Induced DNA Damage Repair Mechanism<br />
Potentiates the Synergistic Efficacy <strong>of</strong> Oncolytic Herpes<br />
Simplex Viral <strong>Therapy</strong> in the Treatment <strong>of</strong> Malignant<br />
Mesothelioma<br />
Prasad S. Adusumilli, Mei-Ki Chan, David P. Eisenberg,<br />
Zhenkun Yu, Karen Hendershott, Ting-Chao Chou, Valerie W.<br />
Rusch, Yuman Fong<br />
Oral Abstract Session 411<br />
Naked DNA <strong>Gene</strong> Transfer: Optimizing Expression/<br />
Animal Models<br />
Room: 260/264<br />
763 10:15 <strong>AM</strong><br />
Optimization <strong>of</strong> Plasmid Components for <strong>Gene</strong> Therapeutic<br />
Purposes<br />
Ruxandra Draghia-Akli, Melissa A. Pope, Amir S. Khan<br />
764 10:30 <strong>AM</strong><br />
RNA and Codon Optimized HIV Candidate Vaccines –<br />
from Bench to Clinical Trials<br />
Ralf Wagner, Petra Mooij, Sunita Balla, Jens Wild, Kurt Bieler,<br />
Hans Wolf, Frank Notka, Jonathan Heeney, Giuseppe Pantaleo<br />
765 10:45 <strong>AM</strong><br />
Intravascular Delivery <strong>of</strong> Naked Plasmid DNA into<br />
Muscle for Long-Term Correction <strong>of</strong> Hyperbilirubinemia<br />
in the Gunn Rat<br />
Istvan Danko, Zhen Jia<br />
766 11:00 <strong>AM</strong><br />
Bone Regeneration Induced by Combining In Vivo<br />
Electroporation <strong>of</strong> an Osteogenic <strong>Gene</strong> and Human<br />
Mesenchymal Stem <strong>Cell</strong>s<br />
Gadi Pelled, A Lazarus, Yoram Zilberman, Eveline Zeira,<br />
Hagit Yotvat, Eithan Galun, Jin Zhong Li, Gregory A. Helm,<br />
Dan Gazit<br />
767 11:15 <strong>AM</strong><br />
Role <strong>of</strong> the Cytoskeleton in Intracellular Plasmid Movement<br />
Erin E. Vaughan, David A. Dean<br />
768 11:30 <strong>AM</strong><br />
Two Distinct Mechanisms, Silencing <strong>of</strong> RNA Expression<br />
and Loss <strong>of</strong> Vector DNA, Are Responsible for the Loss <strong>of</strong><br />
Transgene Expression Following Delivery <strong>of</strong> Foreign<br />
<strong>Gene</strong>s to Skeletal Muscle<br />
Alan R. Brooks, Peiyin Wang, Paul Szymanski, Perry Liu,<br />
Heather Gibson, Hu Sheng Qian, Rick N. Harkins, Gabor M.<br />
Rubanyi<br />
769 11:45 <strong>AM</strong><br />
Tissue Engineering Scaffolds with Non-Viral Vectors:<br />
Sustained and Substrate-Mediated Delivery<br />
Jae-Hyung Jang, Christopher B. Rives, Zain Bengali, Lonnie<br />
D. Shea<br />
770 12:00 PM<br />
Novel Physical Methods for Nonviral DNA Transfer to<br />
Rabbit Retina<br />
Thomas W. Chalberg, Alexander Vankov, Philip Huie, Fanni E.<br />
Molnar, Michele P. Calos, Daniel V. Palanker<br />
Oral Abstract Session 412<br />
Lipid Mediated <strong>Gene</strong> Transfer: Non-Viral Delivery<br />
Systems<br />
Room: 263/267<br />
771 10:15 <strong>AM</strong><br />
Complexes <strong>of</strong> Nucleic Acids with Multivalent Cationic<br />
Lipids for the Study <strong>of</strong> Delivery Pathways and Mechanisms:<br />
From Plasmid DNA to siRNA<br />
Kai Ewert, Nathan F. Bouxsein, Christopher S. McAllister,<br />
Heather M. Evans, Charles E. Samuel, Cyrus R. Safinya<br />
772 10:30 <strong>AM</strong><br />
Convective Flow Increases Lipoplex Delivery Rate to In<br />
Vitro <strong>Cell</strong>ular Monolayers<br />
Steven S. Harris, Todd D. Giorgio<br />
773 10:45 <strong>AM</strong><br />
Role <strong>of</strong> Lipid-Rafts in the Binding and Internalization <strong>of</strong><br />
Dendriplexes and Lipoplexes<br />
Peng H. Tan, Maria Manunta, Andrew J. T. George<br />
774 11:00 <strong>AM</strong><br />
Studies on the Intracellular Release <strong>of</strong> <strong>Gene</strong>tic Drugs<br />
from Pharmaceutical Carriers<br />
Bart Lucas, Katrien Remaut, Stefaan C. De Smedt, Roosmarijn<br />
Vandenbroucke, Joseph Demeester<br />
775 11:15 <strong>AM</strong><br />
Substrate-Mediated DNA Delivery for Neural Tissue<br />
Engineering<br />
Tiffany L. Houchin, Jae-Hyung Jang, Lonnie D. Shea<br />
776 11:30 <strong>AM</strong><br />
A Novel Dual Functioning Non-Viral Vector - Delivering<br />
<strong>Gene</strong>s While Targeting Nuclear Receptor Signaling<br />
Feng Liu, Christine Conwell, Lisa Scollenbergen, Leaf Huang<br />
777 11:45 <strong>AM</strong><br />
Polymer Library Approaches to <strong>Gene</strong> <strong>Therapy</strong><br />
Daniel G. Anderson, Andreas Zumbuehl, Weidan Peng, Janet<br />
A. Sawicki, Robert Langer<br />
778 12:00 PM<br />
Nocodazole Enhances CMV Promoter Activity in a<br />
Human Pancreatic Cancer (Panc 1) <strong>Cell</strong> through Activation<br />
<strong>of</strong> c-Jun<br />
Robert Arpke, Pi-Wan Cheng
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