FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 79<br />
ABSTRACTS<br />
FRIDAY, JUNE 3<br />
548<br />
Ethanol Increases Transgene Expression in Parenchymal<br />
Liver <strong>Cell</strong>s after Adenoviral Transfer in Rabbits<br />
Jan Snoeys, Joke Lievens, Yingmei Feng, Peter Frederik, Désiré<br />
Collen, Eddie Wisse, Bart De Geest<br />
549<br />
Peripheral <strong>Gene</strong> Delivery <strong>of</strong> Glial <strong>Cell</strong> Line-Derived<br />
Neurotrophic Factor Alleviated Neurological Deficits in<br />
Diabetic Rats<br />
Guei-Sheung Liu, Chiou-Lian Lai, Sheng-Long Howng,<br />
Ming-Hong Tai<br />
550<br />
Adenoviral-Mediated Antioxidant Overexpression:<br />
Possible Protective Role Against Hyperglycemic Conditions<br />
in Human Aortic Endothelial <strong>Cell</strong>s<br />
Aoife Duffy, Aaron Liew, Afshin Samali, Timothy O’Brien<br />
551<br />
Enhanced <strong>Cell</strong> Killing Effect <strong>of</strong> E1 Modified<br />
Adenoviruses Expressing HSV-TK Suicide <strong>Gene</strong><br />
Yoon-A Kang, Dong Hyun Ko, Jaesung Kim Kim, Young-Sook<br />
Lee, Oh-Joon Kwon, Joo Hyuk Sohn, Chae-Ok Yun, Joo-<br />
Hang Kim<br />
552<br />
<strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong> Uterine Fibroids: Adenovirus-Mediated<br />
Expression <strong>of</strong> Dominant Negative Estrogen Receptor<br />
Inhibits ERE-Reporter Transactivation in Rat and Human<br />
Leiomyoma <strong>Cell</strong>s<br />
Ayman Al-Hendy<br />
553<br />
A Potent Replicative Delta Adenoviral Vector for HPV<br />
Tumors<br />
Ivan Delgado-Enciso, Irma A. Martinez-Davila, Rocio Ortiz-<br />
Lopez, Ramon Alemany-Bonastre, Christian I. Silva-Platas,<br />
Angel Lugo-Trampe, Hugo A. Barrera-Saldana, Augusto Rojas-<br />
Martinez<br />
554<br />
Evaluation <strong>of</strong> Viral Vector <strong>Gene</strong> Delivery Systems in<br />
Endothelial <strong>Cell</strong>s In Vitro and Ex Vivo<br />
Yanjuan Lin, Anming Xiong, Maria T. Millan<br />
555<br />
An Oncolytic Adenovirus Controlled by a Modified<br />
Telomerase Promoter Is Attenuated in Telomerase-<br />
Negative <strong>Cell</strong>s, but Shows Reduced Activity in Cancer<br />
<strong>Cell</strong>s<br />
Sergia Bortolanza, Qian Cheng, Gabriela M. Kramer, Celia<br />
Gomar, Fabio Farinati, Jesus Prieto, Ruben Hernandez-Alcoceba<br />
Naked DNA <strong>Gene</strong> Transfer: Optimizing Expression,<br />
Animal Models<br />
556<br />
Another Hepatic Control Region for Sustained Expression<br />
<strong>of</strong> Human Factor IX in the Mouse Liver<br />
Ji Eun Lee, Hong Sung Kim, Keun Sik Kim, Eun Jung Kim,<br />
Jong Chul Kim, In Ho Song, Yong Serk Park<br />
557<br />
Unraveling the Molecular Mechanisms Responsible for<br />
Episomal Transgene Silencing In Vivo<br />
Zhi-Ying Chen, Cheng-Yi He, Hui Xu, Mark A. Kay<br />
558<br />
cGMP Production <strong>of</strong> Plasmid DNA for Phase I Clinical<br />
Studies in an Academic Center<br />
Mark Przybylowski, Shirley M. Bartido, Michel Sadelain,<br />
Isabelle Riviere<br />
559<br />
Potentiation <strong>of</strong> DNA Vaccination Using an Integrated<br />
Application System for Electroporation-Mediated<br />
Intramuscular Delivery<br />
Alain Luxembourg, Drew Hannaman, Steve Masterson, Barry<br />
Ellefsen, Gerald Nakamura, Robert Bernard<br />
560<br />
Optimization <strong>of</strong> E. coli Fermentation for Plasmid DNA<br />
Production<br />
Aaron Carnes, Williams James, Hodgson Clague<br />
561<br />
Analytical Characterization <strong>of</strong> Supercoiled Plasmids<br />
Anthony P. Green, Irina Tumanova, Joseph Burzynski, Dana<br />
Rosencrance, Julie Brunbeck, Jason Scheidel, S. Fernando Ausar,<br />
C. Russell Middaugh<br />
562<br />
Study on the Inhibitory Effect <strong>of</strong> Antisense ET R A<br />
Oligodeoxynucleotides for the Proliferation <strong>of</strong> Vascular<br />
Smooth <strong>Cell</strong>s<br />
Lan Zhang, Baigen Zhang, Jiwei Zhang<br />
563<br />
Differential Histone Modifications in Transcriptional<br />
Active Versus Silenced Episomal Vectors In Vivo<br />
Efren Riu, Zhi-Ying Chen, Mark A. Kay<br />
564<br />
Delivery <strong>of</strong> Episomal Vectors Carrying Large Genomic<br />
Regions for <strong>Gene</strong> <strong>Therapy</strong><br />
Wing T. Cheung, Catherine Grillot-Courvalin, Clare Huxley<br />
565<br />
A Ready-to-Use Process for Large-Scale Plasmid DNA<br />
Manufacturing<br />
Astrid Breul, Wayne Tvrdik, Markus Müller, Joachim Schorr
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