FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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64<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
THURSDAY, JUNE 2<br />
301<br />
Down-Regulation <strong>of</strong> bcl-xl <strong>Gene</strong> Expression with bcl-xl<br />
siRNA Vectors In Vitro and In Vivo<br />
Xiaobo X. Cao, Philip Rascoe, Jonathan Daniel, Charles<br />
Rodarte, W. Roy Smythe<br />
302<br />
Herpes Simplex Virus Thymidine Kinase/Ganciclovir<br />
<strong>Therapy</strong> Mediated by Transferrin-Associated Lipoplexes<br />
in a Murine Model for Oral Cancer<br />
Silvia S. Neves, Sergio Simões, Maria C. Pedroso de Lima<br />
303<br />
Validating CD46 as a Possible Mechanism Contributing<br />
to MV-Edm Oncolytic Specificity<br />
Hooi-Tin Ong, Stephen J. Russell, Kah-Whye Peng<br />
304<br />
<strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong> Malignant Brain Tumor by a Novel<br />
Double-Stranded Adeno-Associated Viral (AAV) Vector<br />
Carrying the Decorin <strong>Gene</strong><br />
Chi-Hsien Wang, Jun-Ming Han, Kai-Yun Chen, Shi-Yuan<br />
Cheng, Xiao Xiao, Hsin-I Ma<br />
305<br />
A Safe TRAIL to Lung Tumor Specificity<br />
Juan Shi, Dexian Zheng, Yanxin Liu, Mai Har Sham, Paul<br />
Tam, Farzin Farzaneh, Ruian Xu<br />
306<br />
A Novel Thymidine Kinase in Enhanced Gap Junction<br />
Mediated Suicide <strong>Gene</strong> <strong>Therapy</strong><br />
Tomas J. Ekstrom, Zahidul Khan, Zoran Gojkovic, Mette<br />
Willer, Per M. Almqvist<br />
307<br />
The Tumor-Selective Viral Protein Apoptin Is a Potential<br />
<strong>Gene</strong> Therapeutic Agent for Prostate Cancer <strong>Therapy</strong><br />
Xiang Liu, Ahmed El-Zawhry, David Holman, Saeed<br />
Elojeimy, Alicja Bielawaska, Jacek Bielawaska, Mahvash<br />
Tavassoli, James S. Norris<br />
308<br />
In Vivo Enhancement <strong>of</strong> HSV-TK/GCV Cancer <strong>Gene</strong><br />
<strong>Therapy</strong> with Polyamine Biosynthesis Inhibition<br />
Tiina Wahlfors, Anne Karppinen, Juhani Jänne, Leena<br />
Alhonen, Jarmo Wahlfors<br />
309<br />
STAT5 Phosphorylation in Malignant Melanoma Is<br />
Mediated through SRC and JAK-1 Kinases and Exerts<br />
Anti-Apoptotic Effects<br />
Alireza Mirmohammadsadegh, Walter Bardenheuer, Mohamad<br />
Hassan, Annett Gustrau, Dennis Selimovic, Roya Doroudi,<br />
Nicola Schmittner, Sandeep Nambiar, Alessandra Marini,<br />
Thomas Ruzicka Ulrich R. Hengge<br />
Cancer - Targeted <strong>Gene</strong> <strong>Therapy</strong>: Targeting <strong>of</strong> Non-<br />
Viral Vectors<br />
310<br />
Discovered Peptide Mediates Specific Binding to Primary<br />
Medullary Thyroid Carcinoma after Systemic Injection<br />
Miriam Bockmann, Gero Hilken, Aaron N. Cranston,<br />
Matthias Drosten, Bruce A. J. Ponder, Anke Schmidt, Brigitte<br />
M. Putzer<br />
311<br />
Oncolytic Adenovirus CG5757 Preferentially Infects<br />
Primary Human Tumor Tissues and Shows Strong Anti-<br />
Tumor Activity in Tumor Models Following Systemic<br />
Administration<br />
Yuanhao Li, Trini Arroyo, Stephen Thorne, Tony Reid, Natalie<br />
Nguyen, Neeraja Idamakanti, Melinda VanRoey, Gail Colbern,<br />
De-Chao Yu<br />
312<br />
Human Plasminogen Kringle 5-Engineered Murine<br />
Mammary Cancer <strong>Cell</strong>s Arrest Tumor Growth and<br />
Promote Long-Term Survival<br />
Sabrina R. Perri, Moïra François, Jacques Galipeau<br />
313<br />
Efficacy <strong>of</strong> Group I Intron-Based Trans-Splicing<br />
Ribozyme in Tumor-Targeted <strong>Gene</strong> <strong>Therapy</strong><br />
Byung-Su Kwon, Ju Hyun Kim, Jin-Sook Jeong, In-Hoo<br />
Kim, Seong-Wook Lee<br />
314<br />
The Epithelial Glycoprotein-2 Promoter for Highly<br />
Specific and Efficient Cancer <strong>Gene</strong> <strong>Therapy</strong> for a Broad<br />
Range <strong>of</strong> Tumors<br />
Willemijn M. Gommans, Gerben Duns, Pamela M. J.<br />
McLaughlin, Simone J. van Eert, Masato Yamamoto, David T.<br />
Curiel, Hidde J. Haisma, Marianne G. Rots<br />
315<br />
Highly Specific Expression <strong>of</strong> the Luciferase <strong>Gene</strong> in<br />
Lungs <strong>of</strong> Naïve Nude Mice Directed by Prostate Specific<br />
Antigen Promoter<br />
Hongwei Li, Jin Zhong Li, Gregory A. Helm, Dongfeng Pan<br />
316<br />
Dendritic <strong>Cell</strong>-Based <strong>Gene</strong>tic Immunotherapy for<br />
Prostate Cancer<br />
Briana J. Williams, Nikolay Korokhov, Susan Boling, Linda<br />
Li, Michael Mathis, David T. Curiel<br />
317<br />
Raf-1 siRNA Inhibits Tumor Growth In Vivo<br />
Qixin Leng, A. James Mixson<br />
318<br />
Tumor Growth Inhibition from Tumor Targeted Delivery<br />
<strong>of</strong> Diphtheria Toxin <strong>Gene</strong><br />
Puthupparampil V. Scaria, Qin Zhou, Raymond M. Schiffelers,<br />
Aslam Ansari, Martin C. Woodle
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