FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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108<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
1019<br />
Enhanced Therapeutic Effects <strong>of</strong> Recombinant Adenovirus<br />
Ad-AFPDð19, Selectively Replicating in að-Fetoprotein-Producing<br />
Human Liver Cancer <strong>Cell</strong>s<br />
Il-Kyu Choi, Dong Hyun Ko, Jaesung Kim, Ji-young Yoo, A-<br />
Rum Yoon, Min-Ju Kim, Joo Hyuk Sohn, Chae-Ok Yun, Joo-<br />
Hang Kim<br />
1020<br />
Noninvasive Optical Monitoring <strong>of</strong> Conditionally<br />
Replivative Adenovirus Replication<br />
Julia Davydova, Hidetaka A. Ono, Long P. Le, Tatyana<br />
Gavrikova, Seiji Yamamoto, Amy R. Nelson, David T. Curiel,<br />
Masato Yamamoto<br />
1021<br />
Development <strong>of</strong> a Syrian Hamster Animal Model To<br />
Study Replication Competent Adenovirus Vectors for<br />
Cancer <strong>Gene</strong> <strong>Therapy</strong><br />
Maria A. Thomas, Jacqueline F. Spencer, Karoly Toth, Marie C.<br />
LaRegina, Ann E. Tollefson, Baoling Ying, Mohan<br />
Kuppuswamy, Jennifer M. Meyer, Drew L. Lichtenstein, Louis<br />
A. Zumstein William S. M. Wold<br />
1022<br />
Single-Dose Intravenous Toxicity Study with the Oncolytic<br />
Adenovirus Vector VRX-007, Adenovirus Type 5,<br />
and a Replication-Defective Adenovirus in Syrian<br />
Hamsters<br />
Karoly Toth, Jacqueline F. Spencer, Drew L. Lichtenstein, Ann<br />
E. Tollefson, Jennifer M. Meyer, Maria A. Thomas, Mohan<br />
Kuppuswamy, Baoling Ying, Louis A. Zumstein, William S.<br />
M. Wold<br />
1023<br />
Determination <strong>of</strong> the Maximum Tolerated Dose <strong>of</strong> the<br />
Replication-Competent Adenovirus Vector VRX-007<br />
Following Intravenous Administration in Syrian Hamsters<br />
Maria A. Thomas, Jacqueline F. Spencer, Jennifer M. Meyer,<br />
Marie C. LaRegina, Karoly Toth, Drew L. Lichtenstein, Ann<br />
E. Tollefson, Mohan Kuppuswamy, Baoling Ying, Louis A.<br />
Zumstein William S. M. Wold<br />
1024<br />
An Oncolytic Conditionally Replicating Adenovirus for<br />
Hormone-Dependent and Hormone-Independent<br />
Prostate Cancer<br />
Wing-Shing Cheng, Helena Dzojic, Berith Nilsson, Thomas<br />
H. Totterman, Magnus Essand<br />
1025<br />
A PPT Promoter-Based Adenovirus with Two-Step<br />
Transcriptional Amplification (TSTA) for Experimental<br />
Prostate Cancer<br />
Helena Dzojic, Wing-Shing Cheng, Magnus Essand<br />
1026<br />
In Vivo Imaging for Evaluation <strong>of</strong> Adenoviral Capsid<br />
Modifications for Systemic Delivery in an Orthotopic<br />
Model <strong>of</strong> Locally Advanced Lung Cancer<br />
Merja Särkioja, Anna Kanerva, Tanja Hakkarainen, Jarmo<br />
Salo, Lotta Kangasniemi, Mari Raki, Tuuli Ranki, Hongju<br />
Wu, David T. Curiel, Akseli Hemminki<br />
1027<br />
Cytotoxicity <strong>of</strong> Oncolytic Adenoviruses in Breast Cancer<br />
<strong>Cell</strong>s<br />
M. Bazan-Peregrino, K. Fisher, S. Hale, P. Farrow, D. Kirn, R.<br />
Iggo, K. Homicsko, R. Hernandez-Alcoceba, G. Hallden, V.<br />
Mautner Y. Shen, L. Seymour<br />
1028<br />
Reduction <strong>of</strong> Replication <strong>of</strong> Oncolytic Adenoviruses with<br />
Pharmacological Intervention: Treatment <strong>of</strong> Replication<br />
Associated Toxicity<br />
Anna Kanerva, Mari Raki, Lotta Kangasniemi, Renee A.<br />
Desmond, Helena Isoniemi, Krister Hockerstedt, Akseli<br />
Hemminki<br />
1029<br />
Integrin and Serotype 3 Receptor-Targeted Virotherapy<br />
Using a Telomerase-Selective Oncolytic Adenovirus<br />
Yosuke Kawakami, Angel A. Rivera, Minghui Wang, Dirk M.<br />
Nettelbeck, Mariam A. St<strong>of</strong>f-Khalili, Mack N. Barnes, <strong>Gene</strong> P.<br />
Siegal, Ronald D. Alvarez, David T. Curiel<br />
(Note: Abstract 328 has been moved from Poster<br />
Session I to Poster Session III and will follow Abstract<br />
1029. See page 65 for abstract title and authors.)<br />
Hematologic - New Advances<br />
1030<br />
A Rhesus Macaque Transplant Model for Drug Selection<br />
<strong>of</strong> Hematopoietic Stem <strong>Cell</strong>s Transduced with MGMT<br />
Vectors<br />
Yan Shou, John Gray, Brian Agricola, Zhijun Ma, Derek A.<br />
Persons, Brian P. Sorrentino<br />
1031<br />
Purification <strong>of</strong> <strong>Cell</strong>s with High Aldehyde Dehydrogenase<br />
Activity Reveals a CD133 Negative Population with<br />
Enhanced Repopulating Ability after Ex Vivo Culture<br />
David A. Hess, Louisa Wirthlin, Timothy P. Craft, Phillip E.<br />
Herrbrich, Jan A. Nolta<br />
1032<br />
Hepatocyte Growth Factor Maintains Hematopoietic<br />
Progenitors during Retroviral Transduction<br />
Todd E. Meyerrose, Phillip E. Herrbrich, Michael H. Creer, Jan<br />
A. Nolta
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