FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 109<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
1033<br />
Enhanced Engraftment <strong>of</strong> Retrovirally Transuduced<br />
Hematopoietic Stem <strong>Cell</strong>s Following Treatment with<br />
Diprotin-A<br />
Chaorui Tian, Jessamyn Bagley, Daron Forman, John Iacomini<br />
1034<br />
Automated Retroviral Insertion Site Sequence Analysis<br />
and Mapping Tool followed by Database Analysis<br />
Stephanie Laufs, Frank A. Giordano, Agnes Hotz-Wagenblatt,<br />
Uwe Appelt, Daniel Lauterborn, Kurt Fellenberg, W. Jens Zeller,<br />
Stefan Fruehauf<br />
1035<br />
Use <strong>of</strong> Multi Color p27 kip1 Based Flow Cytometric Assay<br />
To Evaluate and Characterize G 0 to G 1 <strong>Cell</strong> Cycle Related<br />
Changes in Human Hematopoietic <strong>Cell</strong>s after Subjection<br />
to a Clinically Applicable Ex Vivo Transduction Protocol<br />
Jesper Bonde, Ryan Lahey, Phillip Herrbrich, Jan A. Nolta<br />
1036<br />
Engraftment <strong>of</strong> side population Stem <strong>Cell</strong>s in Canine<br />
Recipients<br />
Andrea K. Vaags, David Caton, Krista Halling, Cathy Gartley,<br />
Suzana Rosic-Kablar, Stephen A. Kruth, Margaret R. Hough<br />
1037<br />
Adherent Human Umbilical Cord Blood Derived<br />
Mesenchymal Stem <strong>Cell</strong>s Do Not Augment Viral <strong>Gene</strong><br />
Transfer into Hematopoietic Stem/Progenitor <strong>Cell</strong>s<br />
Todd E. Meyerrose, Phillip E. Herrbrich, Michael H. Creer, Jan<br />
A. Nolta<br />
1038<br />
Lentiviral <strong>Gene</strong> Transfer into HSC Is Enhanced by Early-<br />
Acting Cytokines without Impairing Stem <strong>Cell</strong> Properties<br />
and Involves <strong>Cell</strong>ular Responses Distinct from <strong>Cell</strong><br />
Cycle Control<br />
Francesca Santoni de Sio, Luigi Naldini<br />
1039<br />
Ex Vivo Pre-Selection Increases Marking Following<br />
Transplant <strong>of</strong> Mixtures <strong>of</strong> Bone Marrow from Wild Type<br />
and Green Fluorescent Protein-Methylguanine<br />
Methyltransferase P144K Fusion Protein Transgenic Mice<br />
Uimook Choi, Lanise Cardwell, Natalia Loktionova, Harry L.<br />
Malech<br />
1040<br />
Donor Origin <strong>of</strong> Multipotent Adult Progenitor <strong>Cell</strong>s in<br />
Radiation Chimeras<br />
Morayma Reyes, Sheng Li, En Kimura, Jeffrey S. Chamberlain<br />
1041<br />
Delayed Infusion <strong>of</strong> Hematopoietic Stem <strong>Cell</strong>s Improves<br />
Engraftment after Low-Dose Parenterally Administered<br />
Busulfan in a Congenic Murine Transplant Model<br />
Matthew M. Hsieh, Saskia Langemeijer, Bob Wesley, Elizabeth<br />
M. Kang, John F. Tisdale<br />
1042<br />
Creation <strong>of</strong> Tolerogenic Dendritic <strong>Cell</strong>s by Non Viral<br />
<strong>Gene</strong> Transfer with Immunoliposomes<br />
Peng H. Tan, Sven C. Beutelspacher, Giovanna Lombardi,<br />
Andrew J. T. George<br />
1043<br />
In Vivo <strong>Gene</strong> Transfer into Rat Hematopoietic Stem<br />
<strong>Cell</strong>s Using rSV40 Viral Vectors<br />
Bianling Liu, Jean-Pierre Louboutin, Judy Daviau, David S.<br />
Strayer<br />
1044<br />
Radioprotective <strong>Gene</strong> <strong>Therapy</strong> through Retroviral<br />
Expression <strong>of</strong> Manganese Superoxide Dismutase<br />
Thomas D. Southgate, Victoria Sheard, Michael D. Milsom,<br />
Rob J. Mairs, Marie Boyd, Leslie J. Fairbairn<br />
1045<br />
Overexpression <strong>of</strong> an ABCG2 Multidrug Transporter<br />
Variant Does Not Effect Proliferation or Differentiation<br />
<strong>of</strong> Hematopoetic Stem <strong>Cell</strong>s<br />
Olga Ujhelly, Nora Kucsma, Judith Cervenak, Linping Chen,<br />
Manuel Grez, Balazs Sarkadi, Katalin Nemet<br />
1046<br />
Stable Correction <strong>of</strong> Hematopoietic Stem <strong>Cell</strong>s with<br />
Non-Viral <strong>Gene</strong> Transfer<br />
Meenakshi Noll, Ryan Bennett, Stephen Yant, Mark A. Kay,<br />
Markus Grompe<br />
1047<br />
Chemoprotective <strong>Gene</strong> <strong>Therapy</strong> through Retroviral<br />
Expression <strong>of</strong> the X-Ray Cross Complementing Protein<br />
(XRCC1)<br />
Thomas D. Southgate, Katherine Clarke, Leslie J. Fairbairn<br />
1048<br />
Engineering and Development <strong>of</strong> I-AniI Homing<br />
Endonucleases for <strong>Gene</strong> Correction Applications<br />
Andrew M. Scharenberg, David J. Rawlings, Raymond J.<br />
Monnat, Barry L. Stoddard<br />
1049<br />
Serum Free Fedia Is the Best for Cord Blood Hematopoietic<br />
<strong>Cell</strong>s Expansion<br />
Kamran Alimoghaddam, Mitra Khalili, Masoud Soleimani, Lili<br />
Moezi, Ardeshir Ghavamzadeh