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FINAL PROGR AM - American Society of Gene & Cell Therapy

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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 109<br />

ABSTRACTS<br />

SATURDAY, JUNE 4<br />

1033<br />

Enhanced Engraftment <strong>of</strong> Retrovirally Transuduced<br />

Hematopoietic Stem <strong>Cell</strong>s Following Treatment with<br />

Diprotin-A<br />

Chaorui Tian, Jessamyn Bagley, Daron Forman, John Iacomini<br />

1034<br />

Automated Retroviral Insertion Site Sequence Analysis<br />

and Mapping Tool followed by Database Analysis<br />

Stephanie Laufs, Frank A. Giordano, Agnes Hotz-Wagenblatt,<br />

Uwe Appelt, Daniel Lauterborn, Kurt Fellenberg, W. Jens Zeller,<br />

Stefan Fruehauf<br />

1035<br />

Use <strong>of</strong> Multi Color p27 kip1 Based Flow Cytometric Assay<br />

To Evaluate and Characterize G 0 to G 1 <strong>Cell</strong> Cycle Related<br />

Changes in Human Hematopoietic <strong>Cell</strong>s after Subjection<br />

to a Clinically Applicable Ex Vivo Transduction Protocol<br />

Jesper Bonde, Ryan Lahey, Phillip Herrbrich, Jan A. Nolta<br />

1036<br />

Engraftment <strong>of</strong> side population Stem <strong>Cell</strong>s in Canine<br />

Recipients<br />

Andrea K. Vaags, David Caton, Krista Halling, Cathy Gartley,<br />

Suzana Rosic-Kablar, Stephen A. Kruth, Margaret R. Hough<br />

1037<br />

Adherent Human Umbilical Cord Blood Derived<br />

Mesenchymal Stem <strong>Cell</strong>s Do Not Augment Viral <strong>Gene</strong><br />

Transfer into Hematopoietic Stem/Progenitor <strong>Cell</strong>s<br />

Todd E. Meyerrose, Phillip E. Herrbrich, Michael H. Creer, Jan<br />

A. Nolta<br />

1038<br />

Lentiviral <strong>Gene</strong> Transfer into HSC Is Enhanced by Early-<br />

Acting Cytokines without Impairing Stem <strong>Cell</strong> Properties<br />

and Involves <strong>Cell</strong>ular Responses Distinct from <strong>Cell</strong><br />

Cycle Control<br />

Francesca Santoni de Sio, Luigi Naldini<br />

1039<br />

Ex Vivo Pre-Selection Increases Marking Following<br />

Transplant <strong>of</strong> Mixtures <strong>of</strong> Bone Marrow from Wild Type<br />

and Green Fluorescent Protein-Methylguanine<br />

Methyltransferase P144K Fusion Protein Transgenic Mice<br />

Uimook Choi, Lanise Cardwell, Natalia Loktionova, Harry L.<br />

Malech<br />

1040<br />

Donor Origin <strong>of</strong> Multipotent Adult Progenitor <strong>Cell</strong>s in<br />

Radiation Chimeras<br />

Morayma Reyes, Sheng Li, En Kimura, Jeffrey S. Chamberlain<br />

1041<br />

Delayed Infusion <strong>of</strong> Hematopoietic Stem <strong>Cell</strong>s Improves<br />

Engraftment after Low-Dose Parenterally Administered<br />

Busulfan in a Congenic Murine Transplant Model<br />

Matthew M. Hsieh, Saskia Langemeijer, Bob Wesley, Elizabeth<br />

M. Kang, John F. Tisdale<br />

1042<br />

Creation <strong>of</strong> Tolerogenic Dendritic <strong>Cell</strong>s by Non Viral<br />

<strong>Gene</strong> Transfer with Immunoliposomes<br />

Peng H. Tan, Sven C. Beutelspacher, Giovanna Lombardi,<br />

Andrew J. T. George<br />

1043<br />

In Vivo <strong>Gene</strong> Transfer into Rat Hematopoietic Stem<br />

<strong>Cell</strong>s Using rSV40 Viral Vectors<br />

Bianling Liu, Jean-Pierre Louboutin, Judy Daviau, David S.<br />

Strayer<br />

1044<br />

Radioprotective <strong>Gene</strong> <strong>Therapy</strong> through Retroviral<br />

Expression <strong>of</strong> Manganese Superoxide Dismutase<br />

Thomas D. Southgate, Victoria Sheard, Michael D. Milsom,<br />

Rob J. Mairs, Marie Boyd, Leslie J. Fairbairn<br />

1045<br />

Overexpression <strong>of</strong> an ABCG2 Multidrug Transporter<br />

Variant Does Not Effect Proliferation or Differentiation<br />

<strong>of</strong> Hematopoetic Stem <strong>Cell</strong>s<br />

Olga Ujhelly, Nora Kucsma, Judith Cervenak, Linping Chen,<br />

Manuel Grez, Balazs Sarkadi, Katalin Nemet<br />

1046<br />

Stable Correction <strong>of</strong> Hematopoietic Stem <strong>Cell</strong>s with<br />

Non-Viral <strong>Gene</strong> Transfer<br />

Meenakshi Noll, Ryan Bennett, Stephen Yant, Mark A. Kay,<br />

Markus Grompe<br />

1047<br />

Chemoprotective <strong>Gene</strong> <strong>Therapy</strong> through Retroviral<br />

Expression <strong>of</strong> the X-Ray Cross Complementing Protein<br />

(XRCC1)<br />

Thomas D. Southgate, Katherine Clarke, Leslie J. Fairbairn<br />

1048<br />

Engineering and Development <strong>of</strong> I-AniI Homing<br />

Endonucleases for <strong>Gene</strong> Correction Applications<br />

Andrew M. Scharenberg, David J. Rawlings, Raymond J.<br />

Monnat, Barry L. Stoddard<br />

1049<br />

Serum Free Fedia Is the Best for Cord Blood Hematopoietic<br />

<strong>Cell</strong>s Expansion<br />

Kamran Alimoghaddam, Mitra Khalili, Masoud Soleimani, Lili<br />

Moezi, Ardeshir Ghavamzadeh

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