FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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<strong>AM</strong>ERICAN SOCIETY OF GENE THERAPY • Final Program 111<br />
ABSTRACTS<br />
SATURDAY, JUNE 4<br />
1067<br />
Regulated Expression <strong>of</strong> Biotherapeutic Proteins and<br />
shRNA Using an Ecdysone Receptor-Based <strong>Gene</strong> Switch<br />
Prasanna Kumar, Anand K. Katakam, Chris L. Herold<br />
1068<br />
Luciferase as an In Vivo Reporter for Selective Liver<br />
Repopulation in Adult FAH-/- Mice<br />
Kirk J. Wangensteen, Andy Wilber, Guisheng Zeng, Joel L.<br />
Frandsen, R. Scott McIvor, Stephen C. Ekker, Xin Wang<br />
1069<br />
Increased Antioxidant Levels Following MnSOD-PL<br />
Transfection Results in Increased Radioprotection <strong>of</strong><br />
Normal Tissue but Not Tumor <strong>Cell</strong>s<br />
Michael W. Epperly, Suhua Nie, Xichen Zhang, Joel S.<br />
Greenberger<br />
1070<br />
Easy Search on Clinical <strong>Gene</strong> Transfer: The Euregenethy<br />
(EC-DG Research FP5-TN) Data Base on Pre-Clinical &<br />
Clinical <strong>Gene</strong> Transfer & <strong>Therapy</strong><br />
Odile Y. D. Cohen-Haguenauer, Fatima Bosch, Manuel<br />
Carrondo, Klaus Cichutek, Nicole Deglon, Barbara Demeneix,<br />
George Dickson, Gosta Garhton, Bernd Gansbacher, Cecilia<br />
Melani Luigi Naldini, Felicia Rosenthal, Sandro Rusconi,<br />
Seppo Yla-Herttuala, Heinz Zwierzina<br />
1071<br />
Potential Utility <strong>of</strong> Adipose-Derived Stromal <strong>Cell</strong>s<br />
(ASCs) as a Carrier for Ex Vivo <strong>Gene</strong> <strong>Therapy</strong> – <strong>Gene</strong><br />
Transfer Efficiency <strong>of</strong> ASCs<br />
Rei Ogawa, Hideki Hanawa, Yukihiko Hirai, Toshiyuki<br />
Kurai, Hiroshi Mizuno, Hiko Hyakusoku, Takashi Shimada<br />
1072<br />
Superactivation <strong>of</strong> the SRað and CMV Promoters Using<br />
Designed Zinc Finger Proteins<br />
Victor V. Bartsevich, Andreas Reik, Yuanyue Zhou, Michelle<br />
Kong, Xiao-Yong Li, Lyndon Warfe, Lei Zhang, Casey C.<br />
Case, Trevor Collingwood, Philip D. Gregory Edward J. Rebar<br />
1073<br />
Down-Regulation <strong>of</strong> Epithelial Glycoprotein-2 and<br />
VEGF-D by Engineered Zinc Finger Protein Transcription<br />
Factors<br />
Willemijn M. Gommans, Robbert H. Cool, Pamela M. J.<br />
McLaughlin, Olli H. Laitinen, Seppo Yla-Herttuala, Bert J.<br />
van der Zaal, Hidde J. Haisma, Marianne G. Rots<br />
SUNDAY, JUNE 5<br />
Oral Abstract Session 510<br />
Clinical <strong>Gene</strong> <strong>Therapy</strong><br />
Room: 240 Complex<br />
1074 10:15 <strong>AM</strong><br />
The Use <strong>of</strong> <strong>Gene</strong>tically Modified Antigen Presenting<br />
<strong>Cell</strong>s to <strong>Gene</strong>rate Donor-Derived Virus-Specific Cytotoxic<br />
T Lymphocytes Reactive Against CMV and Adenoviral<br />
Antigens for Clinical Use<br />
Gary D. Myers, Ann Leen, Helen Huls, Elizabeth Buza, Jeff<br />
Chang, Robert A. Krance, George Carrum, Malcolm K.<br />
Brenner, Cliona M. Rooney, Helen E. Heslop Catherine M.<br />
Bollard<br />
1075 10:30 <strong>AM</strong><br />
Phase I Clinical Trial Demonstrates Safety and Feasibility<br />
<strong>of</strong> Autologous <strong>Cell</strong>ular <strong>Therapy</strong> with Lentiviral Modified<br />
CD4 T <strong>Cell</strong>s Expressing Anti-HIV Antisense in Patients<br />
with HAART Resistant HIV-1 Infection<br />
Boro Dropulic, Rob-Roy MacGregor, Tessio Rebello, Peter<br />
Manilla, Laurent Humeau, Xiaobin Lu, Vladimir Slepushkin,<br />
Gwendolyn K. Binder, Cathy Ybarra, Bruce L. Levine Frederic<br />
Bushman, Carl H. June<br />
1076 10:45 <strong>AM</strong><br />
Stable Polyclonal Hematopoietic Repopulation after<br />
Successful Clinical <strong>Gene</strong> <strong>Therapy</strong> <strong>of</strong> Chronic Granulomatous<br />
Disease (CGD)<br />
Manfred Schmidt, Kerstin Schwarzwaelder, Marion G. Ott,<br />
Stefan Stein, Hanno Glimm, Annette Deichmann, Ulrich<br />
Sieler, Dieter Hoelzer, Reinhard Seger, Manuel Grez Christ<strong>of</strong><br />
von Kalle<br />
1077 11:00 <strong>AM</strong><br />
Phase I Clinical Trial <strong>of</strong> Recombinant Adeno-Associated<br />
Virus (rAAV)-Alpha-1 Antitrypsin Vectors<br />
Mark L. Brantly, Margaret Humphries, Sihong Song, Thomas<br />
Conlon, Amy Poirier, Barry J. Byrne, Richard Snyder, Terence<br />
R. Flotte<br />
1078 11:15 <strong>AM</strong><br />
Therapeutic Misconception in Early Phase <strong>Gene</strong> Transfer<br />
Trials<br />
Gail E. Henderson, Michele E. Easter, Catherine Zimmer,<br />
Nancy M. P. King, Arlene M. Davis, Barbra Bluestone<br />
Rothschild, Larry R. Churchill, Benjamin S. Wilfond, Daniel<br />
K. Nelson<br />
1079 11:30 <strong>AM</strong><br />
Successful Myoblast Transplantation to Duchenne<br />
Muscular Dystrophy Patients<br />
Jacques P. Tremblay, Daniel Skuk, Sylvain Michel, Raynald<br />
Roy, Jean-Guy Lachance, Hélène Senay, Deschênes Louise,<br />
Goulet Marlyne, Brigitte Roy, Jean-Pierre Bouchard
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