FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
FINAL PROGR AM - American Society of Gene & Cell Therapy
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80<br />
8th Annual Meeting • June 1 - 5, 2005 • St. Louis<br />
ABSTRACTS<br />
FRIDAY, JUNE 3<br />
566<br />
Silencing <strong>of</strong> Plasmid DNA after Hydrodynamics-Based<br />
Transfection in Mice<br />
Hiroshi Ochiai, Hideyoshi Harashima, Hiroyuki Kamiya<br />
567<br />
Prevention <strong>of</strong> Bilirubin Toxicity in the Gunn Rat by<br />
Long-Term Correction <strong>of</strong> Hyperbilirubinemia with<br />
Liver-Specific Plasmid-Based <strong>Gene</strong> Transfer<br />
Istvan Danko, Zhen Jia<br />
568<br />
In Vitro SFHR-Mediated Modification <strong>of</strong> SMA Locus in<br />
Different Human Trophoblast <strong>Cell</strong>s<br />
Federica Sangiuolo, Antonio Filareto, Paola Spitalieri, Lucia<br />
Scaldaferri, Emanuela Bruscia, Ruggiero Mango, Citro<br />
Gennaro, Massimo De Felici, Giuseppe Novelli<br />
569<br />
Therapeutic Ultrasound for Anti-Angiogenic <strong>Gene</strong><br />
Delivery: Mechanism Studies and Application for<br />
Prostate Tumor<br />
Maayan Duvshani-Eshet, Marcelle Machluf<br />
570<br />
The Effects <strong>of</strong> Cyclic Stretch on the Cytoskeleton and Its<br />
Role in <strong>Gene</strong> Transfer to the Alveolar Epithelium<br />
R. Christopher Geiger, David A. Dean<br />
571<br />
Development <strong>of</strong> a Quantitative Potency Assay for Quality<br />
Control Testing for pVGI.1(VEGF2), a Naked DNA<br />
Vector<br />
Li-chun Huang, Qing Wang, Jiemin Zhou, Hsing-yi Jan,<br />
Yawen L. Chiang<br />
572<br />
Alveolar Epithelial <strong>Cell</strong>-Specific Plasmid Nuclear Import<br />
James V. DeGiulio, David A. Dean<br />
573<br />
Investigation into the Frequency <strong>of</strong> Post-Integrative <strong>Gene</strong><br />
Silencing Using a Non-Selective Sleeping Beauty Transposition<br />
System<br />
Brian S. Garrison, Stephen R. Yant, Jacob G. Mikkelsen, Mark<br />
A. Kay<br />
574<br />
Early Stage Product Development to Scale-Up: Use <strong>of</strong><br />
Mini-Fermentation System for Screening and Process<br />
Development <strong>of</strong> Plasmid DNA Products<br />
Sriram Ramakrishnan, Justin Miller, Jeffrey Darnell, Henry Hebel<br />
575<br />
In Vivo Evaluation <strong>of</strong> Supercoiled Plasmids<br />
Anthony P. Green, Irina Tumanova, Joseph Burzynski, Dana<br />
Rosencrance, Julie White, Jason Scheidel, David Weiner, Jean<br />
Boyer<br />
Lipid Mediated <strong>Gene</strong> Transfer: Non-Viral Delivery<br />
System<br />
576<br />
Hydrophobic Portion <strong>of</strong> Cationic Amphiphiles Are More<br />
Important Than We Think for Transfection Efficiency<br />
Li Wang, Yaeko Hiyama, Harsh Parikh, Robert C. MacDonald<br />
577<br />
Distribution, Time Course, In-Vivo Imaging, Expression<br />
and Inflammatory Response after Non-Viral <strong>Gene</strong><br />
Delivery to Rat and Primate CNS<br />
James G. Hecker, Ellen S. Hauck, Michael H. Nantz, Alice F.<br />
Tarantal<br />
578<br />
Quantitative Evaluation <strong>of</strong> the Relationship between<br />
Efficiency <strong>of</strong> Nuclear Transfer <strong>of</strong> Plasmid DNA and<br />
Trans-<strong>Gene</strong> Expression in Individual <strong>Cell</strong>: Consideration<br />
<strong>of</strong> Mechanism Underlying in the Heterogeneity <strong>of</strong> the<br />
Trans-<strong>Gene</strong> Expression Via Artificial Vector<br />
Hidetaka Akita, Rie Ito, Hiroyuki Kamiya, Kentaro Kogure,<br />
Hideyoshi Harashima<br />
579<br />
In-Vivo Time Course <strong>of</strong> Reporter <strong>Gene</strong> Expression after<br />
Nucleic Acid Delivery to the Lateral Ventricle in Rat<br />
Brain<br />
Ellen S. Hauck, Shaomin Zou, Michael H. Nantz, James G.<br />
Hecker<br />
580<br />
Vitreous - A Barrier to Non-Viral Ocular <strong>Gene</strong> <strong>Therapy</strong><br />
Liesbeth Peeters, Niek N. Sanders, Kevin Braeckmans, Stefaan<br />
C. De Smedt, Joseph Demeester<br />
581<br />
Development <strong>of</strong> a Non-Viral DNA Vector Multifunctional<br />
Envelop-type Nano Device Modified with<br />
Octaarginine Peptide<br />
Kentaro Kogure, Ikramy A. Khalil, Rumiko Moriguchi, Shiroh<br />
Futaki, Hideyoshi Harashima<br />
582<br />
Synthetic siRNA Can Activate the Mammalian Innate<br />
Immune Response in a Sequence Dependent Manner<br />
Adam D. Judge, Janet R. Shaw, Vandana Sood, Kevin<br />
McClintock, Ian MacLachlan<br />
583<br />
The Transgene Expression in the Lung after Systemic<br />
Injection <strong>of</strong> DNA Formulated into Nanoparticles with<br />
Linear PEI Depends <strong>of</strong> Bolus Effect and the Presence <strong>of</strong><br />
Free PEI<br />
Jean Luc Coll, Olivier Freund, Alain Cuzange, Jean Serge<br />
Remy, Jean Paul Behr, Patrick Erbacher<br />
584<br />
<strong>Gene</strong> Delivery to Primary Neuronal <strong>Cell</strong>s<br />
Shaomin Zou, Ellen S. Hauck, Michael H. Nantz, James G.<br />
Hecker
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