Bariatric treatments for adult obesity - Institute of Health Economics

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colorectal or gastroesophageal or fatty liver of osteoarthritis or arthritis orurologic* or mood disorders or birth weight or diarrhea or kidney orgallstone*).m_titl.7. 5 not 68. Bariatrics/9. Weight Loss/10. Anti-Obesity Agents/11. Appetite Depressants/12. diethylpropion/ or phenmetrazine/ or phentermine/ orphenylpropanolamine/13. Sibutramine.tw.14. (reductil or meridia or sibutrex).tw.15. Orlistat.tw.16. (xenical or alli or tetrahydrolipstatin).tw.17. diet therapy/ or diet, carbohydrate-restricted/ or diet fads/ or diet, fatrestricted/or diet, reducing/18. diet.ti.19. Exercise/20. Exercise Therapy/21. exercise.ti.22. Physical Fitness/23. lifestyle.ti.24. life style.ti.25. physical activity.ti.26. walking.ti.27. Behaviour Therapy/28. Cognitive Therapy/29. Psychotherapy/30. Psychotherapy, Group/31. Counseling/32. counseling.ti.33. behavio?ral.ti.34. weight management.ti.35. psychological.ti.36. Patient Education as Topic/37. Health Education/38. modification.ti.39. or/8-3840. limit 39 to "all child (0 to 18 years)"41. limit 40 to "all adult (19 plus years)"42. 39 not (40 not 41)43. limit 42 to animals44. 42 not 4345. limit 44 to yr="2000 - 2010"46. 7 and 4547. meta-analy*.mp,pt.48. ((systematic* adj2 review*) or Medline or pubmed or psychinfo orpsycinfo or search*).tw.49. 47 or 48Bariatric treatments for adult obesity 102
CRD Databases (DARE, HTA& NHS EED)http://nhscrd.york.ac.ukEMBASELicensed Resource(Ovid Platform)2000 –8 April 20102000 –8 April 2010(2010 Week 13)50. (hta or heatlh technology assessment).tw.51. Technology Assessment, Biomedical/52. 50 or 5153. 46 and (49 or 52)366 SRs and HTAs# 1 obes* OR superobes* RESTRICT YR 2000 2010# 2 diet:ti OR lifestyle:ti OR exercise:ti OR walking:ti OR behavioural:tiOR behavioural:ti OR cognitive:ti OR psychological:ti OR modification:ti# 3 "weight loss" OR "weight reduction" OR "weight management" OR"physical activity"# 4 sibutramine OR orlistat OR "appetite suppressants" OR "antiobesityagents" OR counseling OR "cognitive therapy" OR "behavioural therapy"OR psychotherapy OR counseling OR "patient education"# 5 child*:ti NOT adult:ti# 6 #2 OR #3 OR #4# 7 #1 AND #6# 8 #7 NOT #5136 DARE44 HTAs1. *obesity/2. *morbid obesity/3. *diabetic obesity/4. *abdominal obesity/5. or/1-46. (superobes* or obes* or bariatric* or weight).ti.7. (unplanned weight or unintended weight or involuntary weight orantipsychotic* or schizophreni* or bipolar or Parkinson* or Alzheimer* orsmoking or dementia or bulimi* or anorexi* or urinary incontinence or uior pelvic floor or asthma or adhd or attention-deficit or apnea or cancer orcolorectal or gastroesophageal or fatty liver or osteoarthritis or arthritis orcontaceptive* or erectile or urologic* or mood disorders or birth weight ordiarrhea or kidney or gallstone*).ti.8. (5 or 6) not 79. bariatrics/10. weight reduction/11. antiobesity agent/12. exp anorexigenic agent/13. sibutramine/14. sibutramine.tw.15. (reductil or meridia or sibutrex).tw.16. orlistat.tw.17. (xenical or alli or tetrahydrolipstatin).tw.18. diet therapy/19. diet restriction/ or caloric restriction/20. diet therapy/ or diabetic diet/ or low calory diet/ or low fat diet/21. diet.ti.22. exercise/ or aerobic exercise/ or anaerobic exercise/ or aquaticexercise/23. fitness/24. exercise.ti.Bariatric treatments for adult obesity 103
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Alberta STE ReportBariatric treatme
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Alberta STE ReportBariatric treatme
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EXECUTIVE SUMMARYSocial and System
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Three surgical procedures—adjusta
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Costs of Bariatric Surgery and Pote
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Regulatory status .................
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TABLES AND FIGURESSection One: Soci
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ABBREVIATIONSAll abbreviations that
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LYMmMAMDMUHCNANHLBINHSNICENIHNNHNPH
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Bariatric physician: a licensed Doc
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High-density lipoprotein (HDL): a f
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Very-low-calorie diet (VLCD): a die
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Additional Internet searches were c
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This report addresses obesity in ad
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Many systemic factors have been ide
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Severe obesity is associated with d
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eport their height and under-report
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Also using self-reported data from
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An examination of overall obesity d
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Table S.2 presents the associationa
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• have multiple focal points and
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The main problem in any weight mana
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food, and a negative body image. As
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directly causes death. 61 To the ex
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The addition of a selected pharmaco
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lack of formal training in nutritio
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slightly more likely to have prescr
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selection criteria, have facilities
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Barriers to using appropriate baria
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Overview of adult obesityOver the p
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the need for regular physical activ
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phenylpropanolamine/25. Sibutramine
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Complianceand AdherenceDemand andut
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Aetna Clinical PolicyBulletinswww.a
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Overweight 123,821 172,971 157,623
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REFERENCES1. 2006 Canadian clinical
Page 76 and 77: 34. Gostin LO. Fast and supersized:
Page 78 and 79: 69. Klarenbach S, Padwal R, Wiebe N
Page 80 and 81: 105. Hill JO, Thompson H, Wyatt H.
Page 82 and 83: 141. Ross R, Bradshaw AJ. The futur
Page 84 and 85: 172. Arkinson J, Ji H, Fallah S, Pe
Page 86 and 87: This section will address a set of
Page 88 and 89: dietary therapy is to reduce total
Page 90 and 91: Additional benefits of exercise ove
Page 92 and 93: medications that inhibit intestinal
Page 94 and 95: Rimonabant may be considered for pa
Page 96 and 97: Long-term complications are specifi
Page 98 and 99: Devices used for bariatric surgeryH
Page 100 and 101: Description of the Included Systema
Page 102 and 103: AEs for sibutramineAs compared to a
Page 104 and 105: Evidence on Efficacy/EffectivenessW
Page 106 and 107: Table T.7: Effects of behavioural t
Page 108 and 109: SurgeryDescription of the included
Page 110 and 111: follow-up time was 3 years. Results
Page 112 and 113: group as compared to the VBG group.
Page 114 and 115: The authors identified many methodo
Page 116 and 117: The investigators pointed out that
Page 118 and 119: approximately 3 to 5 kilograms. For
Page 120 and 121: for studies with a mean age of part
Page 122 and 123: Examining whether use of any of the
Page 124 and 125: Evidence from placebo-controlled cl
Page 128 and 129: Web of ScienceISI Interface License
Page 130 and 131: AMA Clinical PracticeGuidelineswww.
Page 132 and 133: critical appraisal of the included
Page 134 and 135: APPENDIX T.B: EXCLUDED STUDIESTable
Page 136 and 137: Padwal R, Li SK, Lau DC. Long-term
Page 138 and 139: Quality subsection 1: At least MEDL
Page 140 and 141: Quality subsection 5a:Study quality
Page 142 and 143: Partially reported: The study types
Page 144 and 145: Table T.C.1: Results of quality ass
Page 146 and 147: Table T.C.1: Results of quality ass
Page 148 and 149: APPENDIX T.D: CHARACTERISTICS OF SY
Page 150 and 151: Table T.D.1: Characteristics of the
Page 156 and 157: APPENDIX T.E: EVIDENCE TABLE ON SAF
Page 158 and 159: Serious surgical complicationsSurgi
Page 160 and 161: LSGmMAMDNAnssORQoLRCTRDRRRYGBSBPTGV
Page 162 and 163: Table T.F.1-2: Weight loss - Behavi
Page 164 and 165: Table T.F.1-4: Weight loss - Surger
Page 166 and 167: Table T.F.2: Quality of life (QoL)
Page 168 and 169: Curioni & Lourenco 2005 58Cholester
Page 170 and 171: Table T.F.3-3: Risk factors/comorbi
Page 172 and 173: Table T.F.3-5: Long-term effects of
Page 174 and 175: Maciejewski et al., 2005 65Avenell
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Table T.G.2: Effects of bariatric s
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Table T.G.4: Effects of bariatric s
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18. Cerulli J, Lomaestro BM, Malone
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50. Health Canada Drug Product Data
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SECTION THREE: ECONOMIC EVALUATIONC
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Definition of bariatric surgical pa
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etween surgical interventions, the
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concluded that adding orlistat to L
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Weight management program (WMP) ver
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groups. Compared with standard care
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Results from Analysis of Provincial
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DiscussionThe objectives of the eco
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surgical suites, and so on. The bud
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APPENDIX E.A: LITERATURE SEARCH SUM
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CRD Databases(DARE, HTA & NHS EED)h
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Web of ScienceISI Interface License
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NEOS Librarywww.library.ualberta.ca
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Table E.A.2: Evidence table of revi
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ResultHealth outcomesCostsMarginal
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CostsMarginal analysisThe cost anal
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Time Horizon/discount rateCurrency/
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Objectivestudy perspective: society
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S4Economic burden of obesityMean co
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15. Lacey LA, Wolf A, O'shea D, Ern
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Author Contribution StatementsPaula
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