Bariatric treatments for adult obesity - Institute of Health Economics

Table T.D.2: Characteristics of the primary studies assessed in SRs/HTAsSRs/HTAs Patients InterventionDietary therapy/physical exerciseGalani &Schneider,2007 5630 RCTs (13for preventionstudies, 17 fortreatment)Shaw et al.,2006 5741 RCTsCurioni &Lourenco,2005 586 RCTs13 prevention studiesN = 3566 (range from 74–715)Mean age (yr): 49 (range from 43–62)% female: predominantEthnic origin: Australia, China, England,France, Finland, Italy, Netherlands, Norway,USBaseline weight (kg): mean 81Baseline BMI (kg/m 2 ): mean 28.9 (rangefrom 25–29.7)Comorbidity: hypertension, impaired glucosetolerance, diabetes17 treatment studiesN = 8013 (range from 24 to 2161)Mean age (year): 49 (range from 34 to 69)% female: predominantEthnic origin: Finland, Italy, Sweden, US, UKBaseline weight (kg): NABaseline BMI (kg/m 2 ): 34 (range from 30–37)Comorbidity: hypertension, T2DMN = 3476Age (yr): weighted mean 42.4 in 32 RCTs and range from 20–75 in the remaining nine RCTs% female: of 39 RCTs that reported gender distribution, men 100% in 17 RCTs, women 100% in15 RCTs, and 10 RCTs that included both men and womenEthnic origin: 24 RCTs conducted in the United States, four in the Netherlands, three each inAustralia and Canada, two in Israel, one each in Denmark, Germany, Norway, and the UnitedKingdomBaseline weight (kg): NABaseline BMI (kg/m 2 ): NAComorbidity: NAN = 514 (range from 40–127)Mean age (yr): range from 21–65% female: 100% women in three studies, 100% men in one study, both women and men in twostudiesEthnic origin: four RCTs conducted in US and two RCTs in FinandBaseline weight (kg): mean varied from 83.5–106Baseline BMI (kg/m 2 ): NAComorbidity: NAType: lifestyle intervention including dietary counseling andphysical exercise with or without behavioural modificationtechniquesDuration: 1 to 6 yearsDrop-out rate: range 3%–50% in prevention studies, and4%–38% in treatment studiesLength of follow-up: mean three yearsType: walking (21 trials), exercise bicycle (10 trials), jogging(eight trials), weights training (eight trials), commercial aerobic(five trials), treadmill (five trials), stair stepping (two trials),dancing (one trial), ball games (one trial), calisthenics (onetrial), rowing (one trial), aqua jogging (one trial)No trials evaluated swimming or water aerobics as weight lossinterventions.Duration: NADrop-off rate: < 15% in all studiesLength of follow-up: NAType: any type (not specified)Duration: range from 10–52 weeksDrop-off rate: mean 16.9% (range 9.4–24%)Length of follow-up: 12–24 monthsBariatric treatments for adult obesity 129