Overview <strong>of</strong> <strong>adult</strong> <strong>obesity</strong>Over the past 30 years, <strong>obesity</strong> has become one <strong>of</strong> the most prevalent conditions in countries withdeveloped market economies. It is now recognized as a major public health problem and has beenidentified as an epidemic by the World <strong>Health</strong> Organization and medical organizations around theglobe.Adult <strong>obesity</strong> has emerged as a chronic medical condition characterized by an accumulation <strong>of</strong>excess body fat caused by a long-term energy imbalance that mainly results from a complexinteraction <strong>of</strong> biological, environmental, and behavioural factors.In practice, <strong>adult</strong> <strong>obesity</strong> is defined according to body mass index (BMI), with a BMI <strong>of</strong> 30–34.9kg/m 2 , 35–39.9 kg/m 2 , and 40 kg/m 2 or greater corresponding to mild (class I) <strong>obesity</strong>, moderate(class II) <strong>obesity</strong>, and severe/extreme/morbid (class III) <strong>obesity</strong>, respectively. Because BMI is anindirect measure <strong>of</strong> body composition, a measure <strong>of</strong> central adiposity (that is, waist circumference) isalso recommended as a screening and diagnostic test <strong>for</strong> <strong>adult</strong> <strong>obesity</strong>, to assess more accurately thelevel <strong>of</strong> cardiometabolic risk.Obesity is regarded as a health problem because it is associated with multiple organ-specific andpsychosocial consequences that may result in reduced quality <strong>of</strong> life, increased morbidity, andpremature mortality. The most serious adverse health risks and consequences are associated withsevere (class III) <strong>obesity</strong>.Epidemiology <strong>of</strong> <strong>adult</strong> <strong>obesity</strong>In Canada, as in other countries with developed market economies, the prevalence <strong>of</strong> <strong>obesity</strong> hasincreased steadily within all demographic groups over the past few decades and continues to rise.Class II and class III <strong>obesity</strong> subgroups are experiencing the most rapid increase. The determinants<strong>of</strong> this rapid rise in <strong>obesity</strong> prevalence are many and their complex interactions are still poorlydefined. Obesity prevalence among children and adolescents is increasing at a more rapid pace thanis <strong>adult</strong> <strong>obesity</strong>, causing concern.Self-reported data from surveys <strong>of</strong> nationally representative samples <strong>of</strong> Canadian <strong>adult</strong>sshowed a steady increase in the prevalence <strong>of</strong> <strong>adult</strong> <strong>obesity</strong>, from 6.1% in 1985 to 15.7% in2003 and 17% in 2007. The proportion <strong>of</strong> <strong>adult</strong>s with class II <strong>obesity</strong> increased from 0.8% in1985 to 3% in 2003, and in class III the proportion increased from 0.4% to 1.3%. Directly measured data, which are considered more accurate than self-reported data, suggestthat the prevalence <strong>of</strong> <strong>adult</strong> <strong>obesity</strong> has almost doubled during the past several decades,increasing from 13.8% in 1978–1979 to 23.1% in 2004. The prevalence <strong>of</strong> class II <strong>obesity</strong>increased from 2.3% in 1978–1979 to 5.1% in 2004, while class III <strong>obesity</strong> rates increasedfrom 0.9% to 2.7%.According to the most recently released prevalence rates <strong>for</strong> <strong>adult</strong> <strong>obesity</strong> in Alberta, amongAlberta’s 2007 population <strong>of</strong> 2,619,032 <strong>adult</strong>s (aged 18 years and over), 17.7% were classified asobese (12.5% in class I, 3.7% in class II, and 1.5% in class III <strong>obesity</strong>), based on self-reported datafrom the 2007 CCHS.Women were less likely than men to be classified as obese (15.9% and 19.5%, respectively).<strong>Bariatric</strong> <strong>treatments</strong> <strong>for</strong> <strong>adult</strong> <strong>obesity</strong> 38
Obesity rates increased with age, from 8.1% among <strong>adult</strong>s aged 18 to 24 years to the peak at23.5% among individuals aged 55 to 64 years. The proportion <strong>of</strong> <strong>obesity</strong> drops among theelderly (those over 65 years <strong>of</strong> age).Albertans who are high school graduates are less likely than those who did not graduatefrom high school to be classified as obese (17.2% and 22.5%, respectively).Obesity prevalence rates were higher <strong>for</strong> married and widowed <strong>adult</strong>s (over 19%) than <strong>for</strong>single persons (12.4%) The relationship between <strong>obesity</strong> rates and household annual income did not vary in a linearfashion. Obesity rates were lower (approximately 16%) <strong>for</strong> those in income categories <strong>of</strong> lessthan $20,000 or between $40,000 and $59,000, and higher <strong>for</strong> those with incomes between$20,000 and $39,000 (17.7%) or between $60,000 and $70,000 (19.2%). The highest <strong>obesity</strong>rate (21.6%) was observed in individuals with incomes <strong>of</strong> more than $80,000. Obesity rates were lower in the Edmonton and Calgary zones (17.7% and 14.2%,respectively) than in other health zones in the province, where the rates ranged from 20% to25%.The latest directly measured <strong>adult</strong> <strong>obesity</strong> prevalence rates <strong>for</strong> Alberta were obtained from 2004CCHS data. In 2004, the <strong>adult</strong> <strong>obesity</strong> rate <strong>for</strong> Alberta was 25.2%, with the rates <strong>for</strong> classes I, II, andIII <strong>obesity</strong> being 15.4%, 6.7%, and 3.2%, respectively.Patterns <strong>of</strong> careGiven that long-term maintenance <strong>of</strong> weight loss is difficult to achieve once an individual becomesobese, both prevention strategies (to keep more individuals from becoming obese) and bariatrictreatment strategies (to assist those diagnosed with <strong>obesity</strong> in losing excess weight and keeping it <strong>of</strong>fpermanently) should be considered when addressing <strong>obesity</strong>. A comprehensive and multisectoralapproach to <strong>obesity</strong> prevention is recommended, and effective action requires addressing thecommercial, environmental, and social policy drivers <strong>of</strong> <strong>obesity</strong>. <strong>Health</strong>y behaviours need to besupported by public health measures, such as supportive environments and effective policy changesthat promote healthy weight and prevent <strong>obesity</strong> and its related health risks and consequences.<strong>Bariatric</strong> treatment <strong>for</strong> <strong>adult</strong>s with <strong>obesity</strong>Evidence-based recommendations suggest that bariatric care <strong>for</strong> <strong>adult</strong>s with <strong>obesity</strong> should addressboth the medical and the psychological burdens <strong>of</strong> <strong>obesity</strong>, and include prevention <strong>of</strong> further weightgain. A weight management program based on lifestyle and behavioural modification that includesdietary changes, increased physical activity, and behavioural therapy remains the cornerstone <strong>of</strong>effective bariatric care <strong>for</strong> <strong>adult</strong> <strong>obesity</strong>. Realistic weight loss goals must be clearly defined with theaffected individual, and the treatment plan should be individually tailored based on age, gender,degree <strong>of</strong> <strong>obesity</strong>, individual health risks, cardiometabolic and psychobehavioural characteristics, andoutcome <strong>of</strong> previous weight loss attempts. Pharmacotherapy may be added if lifestyle andbehavioural modification alone are insufficient to achieve clinically significant weight loss. <strong>Bariatric</strong>surgery combined with long-term lifestyle modification may be an appropriate option <strong>for</strong> <strong>adult</strong>s withsevere and moderate <strong>obesity</strong> (when BMI reaches 40 kg/m 2 and even 35 kg/m 2 if it is associated withcomorbidities) who do not respond to appropriate nonsurgical approaches.The therapeutic approach to <strong>adult</strong> <strong>obesity</strong> is multifaceted and complex, particularly <strong>for</strong> severe<strong>obesity</strong>, and is based on intensive patient education and counseling about improving dietary patterns,<strong>Bariatric</strong> <strong>treatments</strong> <strong>for</strong> <strong>adult</strong> <strong>obesity</strong> 39
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Alberta STE ReportBariatric treatme
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Alberta STE ReportBariatric treatme
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EXECUTIVE SUMMARYSocial and System
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Three surgical procedures—adjusta
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Costs of Bariatric Surgery and Pote
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- Page 74 and 75: REFERENCES1. 2006 Canadian clinical
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group as compared to the VBG group.
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The authors identified many methodo
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The investigators pointed out that
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approximately 3 to 5 kilograms. For
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for studies with a mean age of part
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Examining whether use of any of the
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Evidence from placebo-controlled cl
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colorectal or gastroesophageal or f
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Web of ScienceISI Interface License
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AMA Clinical PracticeGuidelineswww.
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critical appraisal of the included
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APPENDIX T.B: EXCLUDED STUDIESTable
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Padwal R, Li SK, Lau DC. Long-term
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Quality subsection 1: At least MEDL
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Quality subsection 5a:Study quality
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Partially reported: The study types
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Table T.C.1: Results of quality ass
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Table T.C.1: Results of quality ass
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APPENDIX T.D: CHARACTERISTICS OF SY
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Table T.D.1: Characteristics of the
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Table T.D.1: Characteristics of the
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Table T.D.2: Characteristics of the
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APPENDIX T.E: EVIDENCE TABLE ON SAF
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Serious surgical complicationsSurgi
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LSGmMAMDNAnssORQoLRCTRDRRRYGBSBPTGV
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Table T.F.1-2: Weight loss - Behavi
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Table T.F.1-4: Weight loss - Surger
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Table T.F.2: Quality of life (QoL)
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Curioni & Lourenco 2005 58Cholester
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Table T.F.3-3: Risk factors/comorbi
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Table T.F.3-5: Long-term effects of
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Maciejewski et al., 2005 65Avenell
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Table T.G.2: Effects of bariatric s
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Table T.G.4: Effects of bariatric s
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18. Cerulli J, Lomaestro BM, Malone
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50. Health Canada Drug Product Data
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SECTION THREE: ECONOMIC EVALUATIONC
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Definition of bariatric surgical pa
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etween surgical interventions, the
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concluded that adding orlistat to L
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Weight management program (WMP) ver
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groups. Compared with standard care
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Results from Analysis of Provincial
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DiscussionThe objectives of the eco
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surgical suites, and so on. The bud
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APPENDIX E.A: LITERATURE SEARCH SUM
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CRD Databases(DARE, HTA & NHS EED)h
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Web of ScienceISI Interface License
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NEOS Librarywww.library.ualberta.ca
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Table E.A.2: Evidence table of revi
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ResultHealth outcomesCostsMarginal
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CostsMarginal analysisThe cost anal
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Time Horizon/discount rateCurrency/
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Objectivestudy perspective: society
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ResultHealth outcomesCostsMarginal
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ResultHealth outcomesCostsMarginal
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S4Economic burden of obesityMean co
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15. Lacey LA, Wolf A, O'shea D, Ern
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Author Contribution StatementsPaula