Bariatric treatments for adult obesity - Institute of Health Economics

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50. Health Canada Drug Product Database. Xenical 120mg capsule. Available at: http://webprod.hcsc.gc.ca/dpd-bdpp/dispatch-repartitiondo?lang-eng 1999 (accessed 18 May 2010).51. Health Canada. Abbott Laboratories voluntarily withdraws weight-loss drug Sibutramine(Meridia) from the Canadian market. Available at: www.hc-sc.gc.ca/ahc-asc/media/advisoriesavis/_2010/2010_169-engphp 2010 October 13 (accessed 28 October 2010).52. European Medicines Agency. European public assessment reports (EPARs). Available at:www.ema.europa eu/ema/index jsp?curl=/pages/medicines/landing/epar_search.jsp 2007 (accessed 21July 2010).53. Obesity Portal. Rimonabant withdrawal 23 October 2008. Available at: www.obesityportalorg/content/rimonabant-withdrawal-23-october-2008 2008 (accessed 21 July 2010).54. Health Canada. Medical Devices Active Licence Listing (MDALL). Available at: www.hcsc.gc.ca/dhp-mps/md-im/licen/mdlic-eng.php2009.55. Sharma AM, Kushner RF. A proposed clinical staging system for obesity. International Journal ofObesity 2009;33:289-95.56. Galani C, Schneider H. Prevention and treatment of obesity with lifestyle interventions: reviewand meta-analysis. International Journal of Public Health 2007;52(6):348-59.57. Shaw K, Gennat H, O'Rourke P, Del Mar C. Exercise for overweight or obesity. CochraneDatabase of Systematic Reviews 2006;(4):003817.58. Curioni CC, Lourenco PM. Long-term weight loss after diet and exercise: a systematic review.International Journal of Obesity 2005;29(10):1168-74.59. Johansson K, Neovius K, Desantis SM, Rossner S, Neovius M. Discontinuation due toadverse events in randomized trials of orlistat, sibutramine and rimonabant: a meta-analysis.Obesity Reviews 2009;10(5):564-75.60. Li Z, Maglione M, Tu W, Mojica W, Arterburn D, Shugarman LR, et al. Meta-analysis:pharmacologic treatment of obesity. Annals of Internal Medicine 2005;142(7):532-46.61. Smartt P. Evidence based review of weight loss medicines: a report commissioned by the New ZealandAccident Compensation Corporation (ACC). Systematic review, 2004.62. Colquitt JL, Picot J, Loveman E, Clegg AJ. Surgery for obesity. Cochrane Database of SystematicReviews 2009;(2):003641.63. Brown T, Avenell A, Edmunds LD, Moore H, Whittaker V, Avery L, et al. Systematic reviewof long-term lifestyle interventions to prevent weight gain and morbidity in adults. ObesityReviews 2009;10(6):627-38.64. Tsai AG. Treatment of obesity in primary care practice in the United States: A systematicreview. Journal of General Internal Medicine 2009;24(9):1073-9.65. Maciejewski ML, Patrick DL, Williamson DF. A structured review of randomized controlledtrials of weight loss showed little improvement in health-related quality of life. Journal of ClinicalEpidemiology 2005;58(6):568-78.66. McTigue K, Harris R, Hemphill MB, Bunton AJ, Lux LJ, Sutton S, et al. Screening andinterventions for overweight and obesity in adults. Systematic review, 2003.Bariatric treatments for adult obesity 158
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Alberta STE ReportBariatric treatme
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Alberta STE ReportBariatric treatme
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EXECUTIVE SUMMARYSocial and System
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Three surgical procedures—adjusta
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Costs of Bariatric Surgery and Pote
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Regulatory status .................
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TABLES AND FIGURESSection One: Soci
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ABBREVIATIONSAll abbreviations that
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LYMmMAMDMUHCNANHLBINHSNICENIHNNHNPH
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Bariatric physician: a licensed Doc
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High-density lipoprotein (HDL): a f
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Very-low-calorie diet (VLCD): a die
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Additional Internet searches were c
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This report addresses obesity in ad
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Many systemic factors have been ide
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Severe obesity is associated with d
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eport their height and under-report
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Also using self-reported data from
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An examination of overall obesity d
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Table S.2 presents the associationa
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• have multiple focal points and
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The main problem in any weight mana
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food, and a negative body image. As
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directly causes death. 61 To the ex
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The addition of a selected pharmaco
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lack of formal training in nutritio
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slightly more likely to have prescr
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selection criteria, have facilities
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Barriers to using appropriate baria
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Overview of adult obesityOver the p
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the need for regular physical activ
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phenylpropanolamine/25. Sibutramine
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Complianceand AdherenceDemand andut
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Aetna Clinical PolicyBulletinswww.a
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Overweight 123,821 172,971 157,623
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REFERENCES1. 2006 Canadian clinical
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34. Gostin LO. Fast and supersized:
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69. Klarenbach S, Padwal R, Wiebe N
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105. Hill JO, Thompson H, Wyatt H.
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141. Ross R, Bradshaw AJ. The futur
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172. Arkinson J, Ji H, Fallah S, Pe
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This section will address a set of
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dietary therapy is to reduce total
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Additional benefits of exercise ove
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medications that inhibit intestinal
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Rimonabant may be considered for pa
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Long-term complications are specifi
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Devices used for bariatric surgeryH
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Description of the Included Systema
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AEs for sibutramineAs compared to a
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Evidence on Efficacy/EffectivenessW
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Table T.7: Effects of behavioural t
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SurgeryDescription of the included
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follow-up time was 3 years. Results
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group as compared to the VBG group.
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The authors identified many methodo
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The investigators pointed out that
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approximately 3 to 5 kilograms. For
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for studies with a mean age of part
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Examining whether use of any of the
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Evidence from placebo-controlled cl
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colorectal or gastroesophageal or f
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Web of ScienceISI Interface License
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AMA Clinical PracticeGuidelineswww.
Page 132 and 133: critical appraisal of the included
Page 134 and 135: APPENDIX T.B: EXCLUDED STUDIESTable
Page 136 and 137: Padwal R, Li SK, Lau DC. Long-term
Page 138 and 139: Quality subsection 1: At least MEDL
Page 140 and 141: Quality subsection 5a:Study quality
Page 142 and 143: Partially reported: The study types
Page 144 and 145: Table T.C.1: Results of quality ass
Page 146 and 147: Table T.C.1: Results of quality ass
Page 148 and 149: APPENDIX T.D: CHARACTERISTICS OF SY
Page 150 and 151: Table T.D.1: Characteristics of the
Page 156 and 157: APPENDIX T.E: EVIDENCE TABLE ON SAF
Page 158 and 159: Serious surgical complicationsSurgi
Page 160 and 161: LSGmMAMDNAnssORQoLRCTRDRRRYGBSBPTGV
Page 162 and 163: Table T.F.1-2: Weight loss - Behavi
Page 164 and 165: Table T.F.1-4: Weight loss - Surger
Page 166 and 167: Table T.F.2: Quality of life (QoL)
Page 168 and 169: Curioni & Lourenco 2005 58Cholester
Page 170 and 171: Table T.F.3-3: Risk factors/comorbi
Page 172 and 173: Table T.F.3-5: Long-term effects of
Page 174 and 175: Maciejewski et al., 2005 65Avenell
Page 176 and 177: Table T.G.2: Effects of bariatric s
Page 178 and 179: Table T.G.4: Effects of bariatric s
Page 180 and 181: 18. Cerulli J, Lomaestro BM, Malone
Page 184 and 185: SECTION THREE: ECONOMIC EVALUATIONC
Page 186 and 187: Definition of bariatric surgical pa
Page 188 and 189: etween surgical interventions, the
Page 190 and 191: concluded that adding orlistat to L
Page 192 and 193: Weight management program (WMP) ver
Page 194 and 195: groups. Compared with standard care
Page 196 and 197: Results from Analysis of Provincial
Page 198 and 199: DiscussionThe objectives of the eco
Page 200 and 201: surgical suites, and so on. The bud
Page 202 and 203: APPENDIX E.A: LITERATURE SEARCH SUM
Page 204 and 205: CRD Databases(DARE, HTA & NHS EED)h
Page 206 and 207: Web of ScienceISI Interface License
Page 208 and 209: NEOS Librarywww.library.ualberta.ca
Page 210 and 211: Table E.A.2: Evidence table of revi
Page 212 and 213: ResultHealth outcomesCostsMarginal
Page 214 and 215: CostsMarginal analysisThe cost anal
Page 216 and 217: Time Horizon/discount rateCurrency/
Page 218 and 219: Objectivestudy perspective: society
Page 224 and 225: S4Economic burden of obesityMean co
Page 226 and 227: 15. Lacey LA, Wolf A, O'shea D, Ern
Page 228 and 229: Author Contribution StatementsPaula
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