Bariatric treatments for adult obesity - Institute of Health Economics

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Table T.C.1: Results of quality assessment for systematic reviewsCriteria Avenell 2 Brown 63 Colguitt 62 Curioni 58Study question established a priori ● ● ● ●Inclusion/exclusion criteria ● ● ● ●Electronic databases ● ● ● ●Searchstrategy1. At least MEDLINE and one other relevantdatabase Other sources ● ● ● ●DataextractionQualityassessmentData analysis/synthesisData extraction method ● 2. Standardized method X ?3. Independent data extraction by at least tworeviewersCriteria used to assess the validity ofincluded studies4. Independent quality assessment by at least tworeviewersX ? X ● ● ●X ? Inter-rater agreement for quality assessment ● ● ●Qualitative review N/A N/A ● N/A5a. Study quality used in analysis or discussion ofstudy resultsN/A N/A N/ASemi-quantitative review N/A N/A N/A N/A5b. Confidence intervals or measures of dispersionreportedN/A N/A N/A N/AMeta-analysis ● ● N/A ●5c. Precision of results reported N/A 5d. Test of heterogeneity conducted X N/A Test for publication bias N/A ●ConcludingsectionConflict/fundingPotential methodologicallimitations/advantages● ● ●Clinical application of results ● ● ●Incorporation of methodological quality ● ●6. Conclusions supported by results Conflict of interest (if any) ● ● ● Sources of funding ● ● ● QualityratingSix criteria in grey areas Average Poor Average GoodBariatric treatments for adult obesity 120
Table T.C.1: Results of quality assessment for systematic reviews (cont’d)CriteriaGalani &Schneider 56 Maciejewski 65 Padwal 20 Poobalan 67Study question established a priori ● ● ● ●Inclusion/exclusion criteria ● ● ●Electronic databases ● ● ● ●Searchstrategy1. At least MEDLINE and one otherrelevant database Other sources ● ● ●DataextractionQualityassessmentData analysis/synthesisData extraction method ● ● ● ●2. Standardized method ? 3. Independent data extraction by at leasttwo reviewersCriteria used to assess the validity ofincluded studies4. Independent quality assessment by atleast two reviewersInter-rater agreement for qualityassessmentX ● ● ● ? X● N/AQualitative review N/A N/A N/A N/A5a. Study quality used in analysis ordiscussion of study resultsN/A N/A N/A N/ASemi-quantitative review N/A N/A N/A N/A5b. Confidence intervals or measures ofdispersion reportedN/A N/A N/A N/AMeta-analysis ● ● ● ●5c. Precision of results reported 5d. Test of homogeneity conducted ? ? XTest for publication bias ● ● ConcludingsectionConflict/fundingPotential methodologicallimitations/advantages● ● ● ●Clinical application of results ● ● ● Incorporation of methodologicalquality● ● ● 6. Conclusions supported by results Conflict of interest (if any) ● ●Sources of funding ● ● ●QualityratingSix criteria in grey areas Average Average Good AverageBariatric treatments for adult obesity 121
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Alberta STE ReportBariatric treatme
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Alberta STE ReportBariatric treatme
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EXECUTIVE SUMMARYSocial and System
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Three surgical procedures—adjusta
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Costs of Bariatric Surgery and Pote
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Regulatory status .................
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TABLES AND FIGURESSection One: Soci
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ABBREVIATIONSAll abbreviations that
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LYMmMAMDMUHCNANHLBINHSNICENIHNNHNPH
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Bariatric physician: a licensed Doc
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High-density lipoprotein (HDL): a f
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Very-low-calorie diet (VLCD): a die
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Additional Internet searches were c
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This report addresses obesity in ad
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Many systemic factors have been ide
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Severe obesity is associated with d
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eport their height and under-report
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Also using self-reported data from
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An examination of overall obesity d
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Table S.2 presents the associationa
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• have multiple focal points and
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The main problem in any weight mana
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food, and a negative body image. As
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directly causes death. 61 To the ex
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The addition of a selected pharmaco
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lack of formal training in nutritio
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slightly more likely to have prescr
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selection criteria, have facilities
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Barriers to using appropriate baria
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Overview of adult obesityOver the p
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the need for regular physical activ
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phenylpropanolamine/25. Sibutramine
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Complianceand AdherenceDemand andut
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Aetna Clinical PolicyBulletinswww.a
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Overweight 123,821 172,971 157,623
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REFERENCES1. 2006 Canadian clinical
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34. Gostin LO. Fast and supersized:
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69. Klarenbach S, Padwal R, Wiebe N
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105. Hill JO, Thompson H, Wyatt H.
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141. Ross R, Bradshaw AJ. The futur
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172. Arkinson J, Ji H, Fallah S, Pe
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This section will address a set of
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dietary therapy is to reduce total
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Additional benefits of exercise ove
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medications that inhibit intestinal
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Page 96 and 97: Long-term complications are specifi
Page 98 and 99: Devices used for bariatric surgeryH
Page 100 and 101: Description of the Included Systema
Page 102 and 103: AEs for sibutramineAs compared to a
Page 104 and 105: Evidence on Efficacy/EffectivenessW
Page 106 and 107: Table T.7: Effects of behavioural t
Page 108 and 109: SurgeryDescription of the included
Page 110 and 111: follow-up time was 3 years. Results
Page 112 and 113: group as compared to the VBG group.
Page 114 and 115: The authors identified many methodo
Page 116 and 117: The investigators pointed out that
Page 118 and 119: approximately 3 to 5 kilograms. For
Page 120 and 121: for studies with a mean age of part
Page 122 and 123: Examining whether use of any of the
Page 124 and 125: Evidence from placebo-controlled cl
Page 126 and 127: colorectal or gastroesophageal or f
Page 128 and 129: Web of ScienceISI Interface License
Page 130 and 131: AMA Clinical PracticeGuidelineswww.
Page 132 and 133: critical appraisal of the included
Page 134 and 135: APPENDIX T.B: EXCLUDED STUDIESTable
Page 136 and 137: Padwal R, Li SK, Lau DC. Long-term
Page 138 and 139: Quality subsection 1: At least MEDL
Page 140 and 141: Quality subsection 5a:Study quality
Page 142 and 143: Partially reported: The study types
Page 146 and 147: Table T.C.1: Results of quality ass
Page 148 and 149: APPENDIX T.D: CHARACTERISTICS OF SY
Page 150 and 151: Table T.D.1: Characteristics of the
Page 156 and 157: APPENDIX T.E: EVIDENCE TABLE ON SAF
Page 158 and 159: Serious surgical complicationsSurgi
Page 160 and 161: LSGmMAMDNAnssORQoLRCTRDRRRYGBSBPTGV
Page 162 and 163: Table T.F.1-2: Weight loss - Behavi
Page 164 and 165: Table T.F.1-4: Weight loss - Surger
Page 166 and 167: Table T.F.2: Quality of life (QoL)
Page 168 and 169: Curioni & Lourenco 2005 58Cholester
Page 170 and 171: Table T.F.3-3: Risk factors/comorbi
Page 172 and 173: Table T.F.3-5: Long-term effects of
Page 174 and 175: Maciejewski et al., 2005 65Avenell
Page 176 and 177: Table T.G.2: Effects of bariatric s
Page 178 and 179: Table T.G.4: Effects of bariatric s
Page 180 and 181: 18. Cerulli J, Lomaestro BM, Malone
Page 182 and 183: 50. Health Canada Drug Product Data
Page 184 and 185: SECTION THREE: ECONOMIC EVALUATIONC
Page 186 and 187: Definition of bariatric surgical pa
Page 188 and 189: etween surgical interventions, the
Page 190 and 191: concluded that adding orlistat to L
Page 192 and 193: Weight management program (WMP) ver
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groups. Compared with standard care
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Results from Analysis of Provincial
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DiscussionThe objectives of the eco
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surgical suites, and so on. The bud
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APPENDIX E.A: LITERATURE SEARCH SUM
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CRD Databases(DARE, HTA & NHS EED)h
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Web of ScienceISI Interface License
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NEOS Librarywww.library.ualberta.ca
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Table E.A.2: Evidence table of revi
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ResultHealth outcomesCostsMarginal
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CostsMarginal analysisThe cost anal
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Time Horizon/discount rateCurrency/
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Objectivestudy perspective: society
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S4Economic burden of obesityMean co
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15. Lacey LA, Wolf A, O'shea D, Ern
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Author Contribution StatementsPaula
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