Bariatric treatments for adult obesity - Institute of Health Economics

Table T.G.4: Effects of bariatric surgery on cancer, mortality, and adverse eventsSurgery group Control group Effect size/P-value (95% CI)Cancer incidenceTotal:126/2010173/20370.71 (P = 0.003)First-time cancer (10 years):In women:11779169130HR 0.67, 95% CI 0.53 to 0.85, P = 0.0009HR 0.58, 95% CI 0.44 to 0.77, P = 0.0001In men:3839HR 0.97, 95% CI 0.62 to 1.52, P = 0.90Mortality (at mean follow-upof 10.9 years)Overall mortality:101/2010 (5.0%)129/2037 (6.3%)Deaths due to cardiac events:13/201025/2037Deaths due to cancer:29/201047/2037Adverse eventsMortality 90-days post surgery:No. of patients withcomplications:5/2010 (0.25%)(4 peritonitis with organfailure; 1 sudden death)151/1164 (13%)2/2037 (0.10%) (1 pancreatic cancer; onealcohol-related)Post-operation requiringreoperation:26/1164 (2.2%)Reoperation or conversion:N = 1338 (for at least 10-year follow-up)Banding: 31%VBG: 21%Gastric bypass: 17%Bariatric treatments for adult obesity 154