Bariatric treatments for adult obesity - Institute of Health Economics

Table T.D.1: Characteristics of the SRs/HTAs (cont’d)Multiple strategiesTsai, 2009 64This review examines the results of RCTs inwhich behavioural weight loss interventions,used alone or with pharmacotherapy, wereprovided in primary care settings.Maciejewski et al., 2005 65To estimate the effect of weight lossinterventions on health-related quality of lifein RCTs; to conduct a meta-analysis of weightloss treatment on depressive symptoms; and,to examine methodological and presentationissues that compromise study validity.Avenell et al., 2004 2To review systematically obesity treatments inadults, to identify therapies that impact byachieving weight reduction, risk factormodification, or improved clinical outcomes.McTigue et al., 2003 66To examine the evidence of the benefits andharms of screening and of earlier treatment inreducing morbidity and mortality fromoverweight and obesity.Databases searched: MEDLINE, EMBASE,Cochrane systemtic review, CINAHLSearch date: 1950 to January 2009Other sources: reference listDatabases searched: MEDLINE,HealthStar, PsychINFOSearch date: 1966 to 2003Other sources: NADatabases searched: 13 databases includingMEDLINE, EMBASE, etcSearch date: MEDLINE (1966 to May 2001),EMBASE (1980 to Week 19 2001)Other source: hand search of specificjournalsDatabases searched: MEDLINESearch date: 1994 to 2001Other sources: NAInclusion criteria:Study: RCTs conducted in the United StatesPatients: adultsIntervention: counseling conducted by primary care providers oranother provider working in the primary care officeExclusion criteria: intervention trials were not primary-care-based;non-US study; pediatric trials; non-intervention trials (e.g., surveys)Inclusion criteria:Study: RCTs published between 1996 and July 2003Patients: adults (≥ 18 years)Intervention: behavioural therapy, pharmacotherapy, and surgeryOutcome measures: QoL, depressive symptomsExclusion criteria: non-English language publication, studies thatfocused on pregnancy-related obesity or gestational diabetesInclusion criteria:Study: RCTs with follow-up ≥ one year; full text articlesPatients: adults (≥ 18 years) with BMI ≥ 28 kg/m 2Intervention: diets, exercise, behavioural therapy, medication, andsurgeryOutcomes: weight loss as a main outcome; no comparison fordietary advice alone with exercise alone for weight managementExclusion criteria: abstractsInclusion criteria:Study: RCTs with at least one year follow-up (six months forpharmacological studies) reporting weight reduction or healthoutcomes for treatment and harms questionsExclusion criteria: NABariatric treatments for adult obesity 127