Vaccines-2013 - OMICS Group

Recommendations

Info

Parth B. Patel, J Vaccines Vaccin 2013, 4:5http://dx.doi.org/10.4172/2157-7560.S1.0183 rd International Conference onVaccines & VaccinationJuly 29-31, 2013 Embassy Suites Las Vegas, NV, USAA review on generation of novel human cancer vaccines testing in phase III clinical trialsParth B. PatelKalol Institute of Pharmacy, IndiaDiscovery of a potential anticancer therapy is still a challenge to the scientists. Though many different kinds of therapies aredeveloped none of them has lived up to the task to cure cancer completely. Cancer vaccines are found to be the latest discoveryin the field of cancer. Although till date only one cancer vaccine is approved by FDA, there are number of vaccines undergoingpreclinical & clinical trials which are promising to be an effective anticancer therapy. This article reviews some of the basic aspectsof different types of cancer vaccines along with their drawbacks & future development. Novel vaccines produce specific immuneresponses and objective clinical responses with minimal toxicity in phase I/II trials. Advances in gene transfer technology, tumorimmunology and better methods of monitoring specific anti tumor immune responses allow the hope that tumor vaccines willbe introduced into the clinic, at least in some malignancies resistant to systemic therapy so far such as melanoma and renal cellcarcinoma. The first generation of human cancer vaccines has been tested in phase III clinical trials, but only a few of these havedemonstrated sufficient efficacy to be licensed for clinical use. This article reviews some of the mechanisms that could contributeto these limited clinical responses, and highlights the challenges faced for development of future vaccines.BiographyParth B. Patel has completed his B. Pharm at the age of 20 years from Gujarat Technological University and postgraduation studies from GujaratTechnological University. He has published two papers in reputed journals and one international book in Lambert Academic Publishing, Germanyas well.parthbpatel91@gmail.comJ Vaccines Vaccin 2013ISSN: 2157-7560, JVV an open access journalVaccines-2013July 29-31, 2013Volume 4 Issue 5Page 152
Prerna Chaudhary, J Vaccines Vaccin 2013, 4:5http://dx.doi.org/10.4172/2157-7560.S1.0183 rd International Conference onVaccines & VaccinationJuly 29-31, 2013 Embassy Suites Las Vegas, NV, USADevelopment of edible vaccine against anthrax by using edema factor gene of Bacillus anthracisPrerna ChaudharyJawaharlal Nehru University, IndiaAnthrax is an epizootic disease mainly affecting cattle, caused by the spore-forming bacterium Bacillus anthracis. It producesthree toxin components, protective antigen (PA), lethal factor (LF) and edema factor (EF). Lethal toxin (LF+PA) and edematoxin (EF+PA) are known to cause lethality in anthrax infected animal models. The recent bioterrorism attack and the revivalof the disease enforce an urgent need for effective prophylactic measures and therapeutic formulations to combat the disease.The currently used PA based anthrax vaccine is associated with several side effects due to its potential reactogenecity and alsorequires protracted and complicated dosages schedule. Since the expression of hepatitis B surface antigen in model plant tobacco,a number of antigenic proteins have been expressed in different plant systems. These plant based vaccines are especially attractiveas plants are free of human or animal diseases, reducing screening and purification costs. Also, they offer a palatable oral deliverysystem that stimulates both systemic and mucosal immune response. Attempts are being made to develop improved anthraxvaccines using antigens other then PA. Several immunization studies have proved that LF and EF alone, produce substantialamount of antibodies and in combination with PA, strengthen PA mediated immunoprotection. Studies have also highlighted theneed of using mutants of anthrax toxin components in vaccine preparations. We have successfully cloned normal and mutatedEF gene in a plant expression vector and Indian mustard plant Brassica juncea was transformed via Agrobacterium mediatedtransformation. Molecular and immunological studies have shown the stable integration and expression of EF gene in the plants.BiographyPrerna Chaudhary is a Ph.D. student at School of Life Sciences, Jawaharlal Nehru University, New Delhi. Currently, she is working on edible vaccineagainst anthrax and recently communicated a paper on PA based edible vaccine.prernajnu@gmail.comJ Vaccines Vaccin 2013ISSN: 2157-7560, JVV an open access journalVaccines-2013July 29-31, 2013Volume 4 Issue 5Page 153
Page 1 and 2:
111 th OMICS Group ConferenceJuly 2
Page 3 and 4:
Medical SciencesISSNAddiction Resea
Page 5 and 6:
Impact Factors (IF) and Index Coper
Page 7 and 8:
111 th OMICS Group Conference3 rd I
Page 9 and 10:
Journal of Clinical & Cellular Immu
Page 11 and 12:
Page 13 and 14:
Page 15 and 16:
Clinical Microbiology-2013OMICS Gro
Page 17 and 18:
Immunology Summit-2013OMICS Group i
Page 19 and 20:
Probiotics-2013OMICS Group is organ
Page 21 and 22:
Virology-2013OMICS Group is organiz
Page 23 and 24:
Page 25 and 26:
Because of heightened awareness of
Page 27 and 28:
Page 29 and 30:
Page 31 and 32:
Page 33 and 34:
Ara Hovanessian, J Vaccines Vaccin
Page 35 and 36:
Nikolai Petrovsky, J Vaccines Vacci
Page 37 and 38:
Page 39 and 40:
Robert E. Sievers et al., J Vaccine
Page 41 and 42:
Xiao-Qing Wei, J Vaccines Vaccin 20
Page 43 and 44:
Campbell Bunce, J Vaccines Vaccin 2
Page 45 and 46:
Hong Xin, J Vaccines Vaccin 2013, 4
Page 47 and 48:
Diane Longo et al., J Vaccines Vacc
Page 49 and 50:
Track 33: Novel Approaches in Desig
Page 51 and 52:
Takashi Kei Kishimoto, J Vaccines V
Page 53 and 54:
Benjamin Petsch, J Vaccines Vaccin
Page 55 and 56:
A. Bennett Jenson et al., J Vaccine
Page 57 and 58:
Milan Raska et al., J Vaccines Vacc
Page 59 and 60:
Muhammad Ali A. Shah et al., J Vacc
Page 61 and 62:
Track 44: Vaccines against Infectio
Page 63 and 64:
Haval Shirwan, J Vaccines Vaccin 20
Page 65 and 66:
Rainer Fischer, J Vaccines Vaccin 2
Page 67 and 68:
Alwyn Rapose, J Vaccines Vaccin 201
Page 69 and 70:
Saroj Basak, J Vaccines Vaccin 2013
Page 71 and 72:
Gisela Gonzalez, J Vaccines Vaccin
Page 73 and 74:
Young Research ForumSession ChairPe
Page 75 and 76:
Humberto Hernandez et al., J Vaccin
Page 77 and 78:
Nisha Nair et al., J Vaccines Vacci
Page 79 and 80:
Leow Yee et al., J Vaccines Vaccin
Page 81 and 82:
Kaissar Tabynov et al., J Vaccines
Page 83 and 84:
Teena Mohan et al., J Vaccines Vacc
Page 85 and 86:
Track 5 & 95: Manufacturing, Produc
Page 87 and 88:
Graham Clarke, J Vaccines Vaccin 20
Page 89 and 90:
Obradovic Zarema et al., J Vaccines
Page 91 and 92:
Abdur Razzaque Sarker et al., J Vac
Page 93 and 94:
Omer Qutaiba B. Al-lela et al., J V
Page 95 and 96:
Page 97 and 98:
Regina Heidenreich et al., J Vaccin
Page 99 and 100:
Leow Y et al., J Vaccines Vaccin 20
Page 101 and 102: Zafer Kurugol et al., J Vaccines Va
Page 103 and 104: Ates Kara et al., J Vaccines Vaccin
Page 105 and 106: Yurong Tan et al., J Vaccines Vacci
Page 107 and 108: Deryabin P.N. et al., J Vaccines Va
Page 109 and 110: Xiao-Yong Fan et al., J Vaccines Va
Page 111 and 112: Byung Chul Kim et al., J Vaccines V
Page 113 and 114: STS. Chitradevi et al., J Vaccines
Page 115 and 116: Yan Liang et al., J Vaccines Vaccin
Page 117 and 118: 111 th OMICS Group Conference3 rd I
Page 119 and 120: Afshineh Latifynia et al., J Vaccin
Page 121 and 122: Hemanta Koley et al., J Vaccines Va
Page 123 and 124: Aleksandar Masic et al., J Vaccines
Page 125 and 126: Hassen Mamo, J Vaccines Vaccin 2013
Page 127 and 128: Oladipo Aina et al., J Vaccines Vac
Page 129 and 130: Aiswariya Chidambaram, J Vaccines V
Page 131 and 132: Birhanu Hurisa et al., J Vaccines V
Page 133 and 134: Ghaffarifar F et al., J Vaccines Va
Page 135 and 136: Mathan Periasamy et al., J Vaccines
Page 137 and 138: Rania Abdel Hay, J Vaccines Vaccin
Page 139 and 140: Samuel Teshome, J Vaccines Vaccin 2
Page 141 and 142: 111 th OMICS Group Conference3 rd I
Page 143 and 144: Birhanu Hurisa et al., J Vaccines V
Page 145 and 146: Dhrubajyoti Nag, J Vaccines Vaccin
Page 147 and 148: Belachew Etana et al., J Vaccines V
Page 149 and 150: Fatemeh Ghaffarifar et al., J Vacci
Page 151: Moustafa A.F. Abbas et al., J Vacci
Page 155 and 156: Sandeepkumar R. Chauhan et al., J V
Page 157 and 158: Veronica Rainone et al., J Vaccines
Page 159 and 160: Page 159
Page 161 and 162: Previous111 th OMICS Group Conferen
Page 163 and 164: PreviousWorld Congress and Expo onB
show all

Vaccines-2013 - OMICS Group

Create successful ePaper yourself

Delete template?

Save as template?