CONTENTS

J.Res. ANGRAU 41(2) 78-85, 2013
EFFICACY OF CONTROLLED INTERNAL DRUG RELEASING (CIDR)
DEVICE ON SYNCHRONIZATION OF ESTRUS AND FERTILITY IN EWES
K. MURALI MOHAN, K. SADASIVA RAO and K.G. SOLMON RAJU
Department of Veterinary Gynaecology and Obstetrics, College of Veterinary Science,
Sri Venkateswara Veterinary University, Rajendranagar, Hyderabad – 5000 30
Date of Receipt : 23.01.2013 Date of Acceptance : 28.03.2013
ABSTRACT
The present study was aimed to determine the efficacy of CIDR for synchronization of estrus in ewes. The
ewes were synchronized with controlled internal drug releasing (CIDR) device containing 300 mg of progesterone.
A total of 120 post partum, parous, healthy ewes aged about 2 to 5 years were divided into 5 groups and each group
consists of 24 animals. Each group was further subdivided into 2 groups that consists of 12 animals and were
studied during breeding and non breeding seasons. Group I ewes were considered as untreated control. Ewes in
Group II were treated with CIDR and were left in place for 12 days followed by intramuscular injection of 400 IU of
PMSG at the time of device removal. Ewes in Group III were treated with CIDR and 600 IU of PMSG was given
intramuscularly at the time of removal of CIDR. Ewes in Group IV were treated as in Group II and additionally
supplementation 200 IU of hCG injection at the time of mating. Ewes in Group V were treated as in Group III and
additional injection of 200 IU of hCG at the time of mating. The percentage of ewes responded for synchronization
of estrus was 50.00, 83.33, 100.00, 91.67 and 100.00 in breeding season. While during non breeding season, the
same was 16.67, 83.33, 100.00, 83.33 and 100.00 per cent in Group I, II, III, IV and V, respectively. The time taken for
induction of estrus was low in ewes treated with CIDR during breeding season when compared to that of non
breeding season. The duration of estrus was ranged between 42.68±4.80 to 43.40±4.44 h in different treatment
groups during breeding season. The pregnancy rate was 50.00, 70.00, 83.33, 72.72 and 91.67 per cent in ewes
treated during breeding season and 50.00, 60.00, 75.00, 70.00 and 83.33 per cent during non breeding season in
Group I, II, III, IV and V, respectively. Statistical analysis revealed that treatment with CIDR and season of treatment
had significantly (P