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Air Quality Guidelines Global Update 2005 - World Health ...

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156<br />

AIR QUALITY GUIDELINES<br />

in 12 European countries (11). Applying dose−response information, primarily<br />

from industrialized countries, the <strong>World</strong> Bank estimated the benefits of air pollution<br />

control in Mexico City (12). Recently, Hubbell et al. (13) estimated both<br />

the health and economic effects associated with exposure to current levels of<br />

ground-level ozone in the United States, while USEPA (14,15) estimated the effects<br />

associated with meeting alternative ambient standards for fine PM. An assessment<br />

was conducted on the health impacts of air pollution and the potential<br />

benefits of current and future control strategies in Europe under the Clean <strong>Air</strong><br />

for Europe (CAFE) programme (16,17). Additional methodological guidance for<br />

estimating the health effects of air pollution is provided by Ostro (18) as part<br />

of WHO’s Environmental Burden of Disease project, the USEPA Clean <strong>Air</strong> Act<br />

Compliance Council (an independent scientific review panel for USEPA) (19),<br />

the US National Research Council (20), the <strong>World</strong> <strong>Health</strong> Organization (21) and<br />

from Europe, ExternE (22) and Sanderson & Hurley (23).<br />

Finally, statistical software to calculate HIA is available (e.g. BenMAP from<br />

USEPA and <strong>Air</strong>Q 2.2.3 from the WHO Regional Office for Europe), although decisions<br />

on which epidemiological studies to use and how to apply them are left to<br />

the software user. All of these efforts use CR functions culled from the epidemiological<br />

literature, relating changes in air pollution measured at fixed site monitors<br />

to increases in mortality and morbidity.<br />

Inputs for the analysis<br />

For a given city, country or region, quantitative assessment of the health impact<br />

of outdoor air pollution is based on four components: (a) pre- and post-air-pollution<br />

concentrations and exposure assessment; (b) size and composition of population<br />

groups exposed to current levels of air pollution; (c) background incidence<br />

of mortality and morbidity; and (d) CR functions (Fig 1).<br />

Pre- and post-air-pollution concentrations<br />

Analysts need to determine the current exposure of the population to ambient<br />

pollution, based either on existing fixed-site monitors or on model-based estimates.<br />

Ideally, these concentrations are based on several recent years of complete<br />

data (to reduce the influence of an atypical year or season) from monitors that<br />

are reasonably representative of population exposure. The monitors should not<br />

be unduly influenced by local sources such as a nearby highway, factory or power<br />

plant but should rather reflect exposures over a wide area. Typically, fixed-site,<br />

population-oriented monitors have been averaged across a metropolitan area<br />

to characterize air quality in epidemiological studies. Therefore, a similar metric<br />

should be used in HIA. As an alternative to measured pollution concentrations,<br />

the global burden of disease project relied on economic models to estimate<br />

pollution concentrations for cities throughout the world (2). Besides the<br />

current concentration, the analyst needs to determine a counterfactual such as

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